Applying newer parameter Ret‐He (reticulocyte haemoglobin equivalent) to assess latent iron deficiency (LID) in blood donors–study at a tertiary care hospital in India

It is important to detect Latent Iron Deficiency (LID) to prevent development of an overt iron deficiency anemia. Early detection is difficult by using conventional hematological and biochemical parameters. Soluble transferrin receptor (sTfR) is presently the gold standard for diagnosing LID. We evaluated the utility of Reticulocyte Hemoglobin Equivalent (Ret‐He), a newer hematological parameter, to predict LID in blood donors as compared to sTfR.

[1]  M. Ucar,et al.  The Importance of RET-He in the Diagnosis of Iron Deficiency and Iron Deficiency Anemia and the Evaluation of Response to Oral Iron Therapy , 2019, Journal of medical biochemistry.

[2]  R. Srivastava,et al.  Distribution of ABO and Rh types in voluntary Blood donors in Jharkhand area as a study conducted by RIMS, Ranchi , 2016, Journal of family medicine and primary care.

[3]  L. Borque,et al.  Clinical Value of Hypochromia Markers in the Detection of Latent Iron Deficiency in Nonanemic Premenopausal Women , 2016, Journal of clinical laboratory analysis.

[4]  S. Kumari,et al.  Prevalence and pattern of anemia among persons reported for blood donation at a tertiary care center in western part of Rajasthan , 2016 .

[5]  N. Marwaha,et al.  A Randomized Control Study to Evaluate Effects of Short-term Oral Iron Supplementation in Regular Voluntary Blood Donors , 2016, Indian Journal of Hematology and Blood Transfusion.

[6]  Amar Shah,et al.  Knowledge and awareness about Iron deficiency and megaloblastic anaemia among blood donors: a study at rural based tertiary care hospital , 2015 .

[7]  Madeeha Kamal,et al.  Early Diagnosis of Iron Deficiency in School Children: A Qatari Experience , 2015 .

[8]  R. Kumar,et al.  Screening of β-thalassemia trait and other hemoglobinopathies among blood donors in Punjab , 2015 .

[9]  K. Park,et al.  Park's Textbook of Preventive and Social Medicine , 2015 .

[10]  P. Maslak,et al.  Using the hemoglobin content of reticulocytes (RET-He) to evaluate anemia in patients with cancer. , 2014, American journal of clinical pathology.

[11]  M. Pal,et al.  EFFECT OF FREQUENT BLOOD DONATION ON IRON STATUS OF BLOOD DONORS IN BURDWAN, WEST BENGAL, INDIA , 2013 .

[12]  I. Cavill,et al.  Guideline for the laboratory diagnosis of functional iron deficiency , 2013, British journal of haematology.

[13]  P. Urdal,et al.  Reticulocyte hemoglobin equivalent to detect thalassemia and thalassemic hemoglobin variants , 2012, International journal of laboratory hematology.

[14]  A. Bharti,et al.  Screening for Hemoglobinopathies in blood donors from Eastern Uttar Pradesh, India. , 2012 .

[15]  Jorge Gómez,et al.  Prevalence of Anaemia and Evaluation of Transferrin Receptor (sTfR) in the Diagnosis of Iron Deficiency in the Hospitalized Elderly Patients: Anaemia Clinical Studies in Chile , 2012, Anemia.

[16]  D. Dietzen,et al.  Reticulocyte hemoglobin content , 2008, American journal of hematology.

[17]  S. Gupte,et al.  Iron status of regular voluntary blood donors , 2008, Asian journal of transfusion science.

[18]  G. Zini,et al.  Reticulocyte hemoglobin equivalent: an indicator of reduced iron availability in chronic kidney diseases during erythropoietin therapy. , 2007, Laboratory hematology : official publication of the International Society for Laboratory Hematology.

[19]  Neelam Marwaha,et al.  Evaluation of iron stores in blood donors by serum ferritin. , 2006, The Indian journal of medical research.

[20]  C. Brugnara,et al.  Reticulocyte hemoglobin equivalent (Ret He) and assessment of iron-deficient states , 2006, Clinical and laboratory haematology.

[21]  J. Wish.  Assessing iron status: beyond serum ferritin and transferrin saturation. , 2006, Clinical journal of the American Society of Nephrology : CJASN.

[22]  Á. Remacha,et al.  Clinical utility of the new Sysmex XE 2100 parameter - reticulocyte hemoglobin equivalent - in the diagnosis of anemia. , 2005, Haematologica.

[23]  Rolf,et al.  Iron Metabolism, Iron Deficiency and Anaemia From Diagnosis to Treatment and Monitoring , 2004 .

[24]  O. Platt,et al.  Reticulocyte hemoglobin: an integrated parameter for evaluation of erythropoietic activity. , 1997, American journal of clinical pathology.

[25]  K. Punnonen,et al.  Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. , 1997, Blood.