Supplementary Methods

The first step of NACHO is the summarize step. To illustrate the procedures in NACHO an example is given based on public data obtained from the public repository Gene Expression Omnibus (GEO). For this example data is used that is composed of 734 microRNAs from 246 individuals and consists of microRNA signatures of patients with nasopharyngeal carcinoma at varying stages of the disease from two independent cohorts[1].

[1]  K. Hagino-Yamagishi,et al.  [Oncogene]. , 2019, Gan to kagaku ryoho. Cancer & chemotherapy.

[2]  E. Abraham,et al.  MicroRNA let-7c Regulates Macrophage Polarization , 2013, The Journal of Immunology.

[3]  D. Kosman,et al.  Ferroportin and Exocytoplasmic Ferroxidase Activity Are Required for Brain Microvascular Endothelial Cell Iron Efflux* , 2013, The Journal of Biological Chemistry.

[4]  E. van Rooij,et al.  miRNA-21 is dysregulated in response to vein grafting in multiple models and genetic ablation in mice attenuates neointima formation , 2013, European heart journal.

[5]  H. Kestler,et al.  A fluorescent reporter for mapping cellular protein-protein interactions in time and space , 2013, Molecular systems biology.

[6]  Lincoln D. Stein,et al.  Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes , 2012, Nature.

[7]  Joseph G Ibrahim,et al.  Missing data in clinical studies: issues and methods. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[8]  Grant W. Brown,et al.  Dissecting DNA damage response pathways by analyzing protein localization and abundance changes during DNA replication stress , 2012, Nature Cell Biology.

[9]  Kevin W Eliceiri,et al.  NIH Image to ImageJ: 25 years of image analysis , 2012, Nature Methods.

[10]  Ying Sun,et al.  Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. , 2012, The Lancet. Oncology.

[11]  C. Grant,et al.  The Response to Heat Shock and Oxidative Stress in Saccharomyces cerevisiae , 2012, Genetics.

[12]  Pablo Cingolani,et al.  © 2012 Landes Bioscience. Do not distribute. , 2022 .

[13]  C. Lo,et al.  MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation , 2012, Circulation research.

[14]  D. Kosman,et al.  Mechanistic analysis of iron accumulation by endothelial cells of the BBB , 2012, BioMetals.

[15]  Ken Chen,et al.  SomaticSniper: identification of somatic point mutations in whole genome sequencing data , 2012, Bioinform..

[16]  J. Norman,et al.  Rab25 and CLIC3 Collaborate to Promote Integrin Recycling from Late Endosomes/Lysosomes and Drive Cancer Progression , 2012, Developmental cell.

[17]  Jennifer P Morton,et al.  MicroRNA Molecular Profiles Associated with Diagnosis, Clinicopathologic Criteria, and Overall Survival in Patients with Resectable Pancreatic Ductal Adenocarcinoma , 2011, Clinical Cancer Research.

[18]  Ying Li,et al.  TREAT: a bioinformatics tool for variant annotations and visualizations in targeted and exome sequencing data , 2011, Bioinform..

[19]  A. Colombo,et al.  Inhibition of In-Stent Stenosis by Oral Administration of Bindarit in Porcine Coronary Arteries , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[20]  J. Rinn,et al.  Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. , 2011, Genes & development.

[21]  B. Ponder,et al.  Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1. , 2011, Neoplasia.

[22]  Yusuke Nakamura,et al.  Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker , 2011, Cancer science.

[23]  B. Ponder,et al.  Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer , 2011, Molecular Cancer.

[24]  B. Ponder,et al.  Abstract 3019: Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells , 2011 .

[25]  M. DePristo,et al.  A framework for variation discovery and genotyping using next-generation DNA sequencing data , 2011, Nature Genetics.

[26]  M. Mann,et al.  Andromeda: a peptide search engine integrated into the MaxQuant environment. , 2011, Journal of proteome research.

[27]  N. Johnsson,et al.  A constraint network of interactions: protein–protein interaction analysis of the yeast type II phosphatase Ptc1p and its adaptor protein Nbp2p , 2011, Journal of Cell Science.

[28]  S. Kauppinen,et al.  Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. , 2010, The Journal of clinical investigation.

[29]  N. Dohmae,et al.  Automated protein hydrolysis delivering sample to a solid acid catalyst for amino acid analysis. , 2010, Analytical chemistry.

[30]  C. Dart,et al.  Interaction with caveolin‐1 modulates vascular ATP‐sensitive potassium (KATP) channel activity , 2010, The Journal of physiology.

[31]  M. DePristo,et al.  The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. , 2010, Genome research.

[32]  Yi Zhang,et al.  Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification , 2010, Nature.

[33]  Mattias Goksör,et al.  CellStress - open source image analysis program for single-cell analysis , 2010, NanoScience + Engineering.

[34]  Andreas Ziegler,et al.  On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data , 2010, Bioinform..

[35]  Peter Kraft,et al.  Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. , 2010, Human molecular genetics.

[36]  Geoffrey S. Tobias,et al.  Pancreatic cancer risk and ABO blood group alleles: results from the pancreatic cancer cohort consortium. , 2010, Cancer research.

[37]  Susan R. Johnson,et al.  Timing of alcohol use and the incidence of premenstrual syndrome and probable premenstrual dysphoric disorder. , 2009, Journal of women's health.

[38]  Gary D. Bader,et al.  Bayesian Modeling of the Yeast SH3 Domain Interactome Predicts Spatiotemporal Dynamics of Endocytosis Proteins , 2009, PLoS biology.

[39]  Frank Speleman,et al.  A novel and universal method for microRNA RT-qPCR data normalization , 2009, Genome Biology.

[40]  D. G. Gibson,et al.  Enzymatic assembly of DNA molecules up to several hundred kilobases , 2009, Nature Methods.

[41]  S. Bradshaw,et al.  A practical method to rapidly dissolve metallic stents. , 2009, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

[42]  Michael C. Schatz,et al.  CloudBurst: highly sensitive read mapping with MapReduce , 2009, Bioinform..

[43]  Joseph G. Ibrahim,et al.  Missing data methods in longitudinal studies: a review , 2009 .

[44]  Yaniv Lubling,et al.  Distinct Modes of Regulation by Chromatin Encoded through Nucleosome Positioning Signals , 2008, PLoS Comput. Biol..

[45]  Bin Ma,et al.  ZOOM! Zillions of oligos mapped , 2008, Bioinform..

[46]  Gonzalo Vera,et al.  BMC Bioinformatics , 2005 .

[47]  Mikael Käll,et al.  Image analysis algorithms for cell contour recognition in budding yeast. , 2008, Optics express.

[48]  M. Gerstein,et al.  The Transcriptional Landscape of the Yeast Genome Defined by RNA Sequencing , 2008, Science.

[49]  C. Snowdon,et al.  Components of the Vid30c are needed for the rapamycin-induced degradation of the high-affinity hexose transporter Hxt7p in Saccharomyces cerevisiae. , 2008, FEMS yeast research.

[50]  G. Curhan,et al.  24-h uric acid excretion and the risk of kidney stones. , 2008, Kidney international.

[51]  Oliver J. Rando,et al.  Chromatin remodelling at promoters suppresses antisense transcription , 2007, Nature.

[52]  Ronald W. Davis,et al.  A high-resolution atlas of nucleosome occupancy in yeast , 2007, Nature Genetics.

[53]  F. Domann,et al.  AP-2 participates in the transcriptional control of the amyloid precursor protein (APP) gene in oral squamous cell carcinoma. , 2007, Experimental and molecular pathology.

[54]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[55]  Xiao-Hua Zhou,et al.  Multiple imputation: review of theory, implementation and software , 2007, Statistics in medicine.

[56]  A. Mortazavi,et al.  Genome-Wide Mapping of in Vivo Protein-DNA Interactions , 2007, Science.

[57]  W. Willett,et al.  A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer , 2007, Nature Genetics.

[58]  P. Fearnhead,et al.  Genome-wide association study of prostate cancer identifies a second risk locus at 8q24 , 2007, Nature Genetics.

[59]  D. Greaves,et al.  Increased in-stent stenosis in ApoE knockout mice: insights from a novel mouse model of balloon angioplasty and stenting. , 2007, Arteriosclerosis, thrombosis, and vascular biology.

[60]  I. Albert,et al.  Translational and rotational settings of H2A.Z nucleosomes across the Saccharomyces cerevisiae genome , 2007, Nature.

[61]  C. Liang,et al.  In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro , 2007, Nature Protocols.

[62]  M. Hattori,et al.  A large-scale full-length cDNA analysis to explore the budding yeast transcriptome , 2006, Proceedings of the National Academy of Sciences.

[63]  I. Albert,et al.  Nucleosome positions predicted through comparative genomics , 2006, Nature Genetics.

[64]  Irene K. Moore,et al.  A genomic code for nucleosome positioning , 2006, Nature.

[65]  Raman M. Das,et al.  A robust system for RNA interference in the chicken using a modified microRNA operon. , 2006, Developmental biology.

[66]  P. M. Galetti,et al.  A tandemly repetitive centromeric DNA sequence of the fish Hoplias malabaricus (Characiformes: Erythrinidae) is derived from 5S rDNA , 2006, Genetica.

[67]  B. Wickes,et al.  Split marker transformation increases homologous integration frequency in Cryptococcus neoformans. , 2006, Fungal genetics and biology : FG & B.

[68]  Ting Wang,et al.  An improved map of conserved regulatory sites for Saccharomyces cerevisiae , 2006, BMC Bioinformatics.

[69]  B. Jørgensen,et al.  Biogeographical distribution and diversity of microbes in methane hydrate-bearing deep marine sediments on the Pacific Ocean Margin. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[70]  B. Haarer,et al.  Role of a Cdc42p effector pathway in recruitment of the yeast septins to the presumptive bud site. , 2005, Molecular biology of the cell.

[71]  J. Widengren,et al.  FCS cell surface measurements—Photophysical limitations and consequences on molecular ensembles with heterogenic mobilities , 2005, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[72]  Y. Yu,et al.  Analysis of community structures in anaerobic processes using a quantitative real-time PCR method. , 2005, Water science and technology : a journal of the International Association on Water Pollution Research.

[73]  François Nicolas,et al.  Hardness of optimal spaced seed design , 2005, J. Comput. Syst. Sci..

[74]  W. Kuis,et al.  Improved multiplex immunoassay performance in human plasma and synovial fluid following removal of interfering heterophilic antibodies. , 2005, Journal of immunological methods.

[75]  Wing-Yiu Choy,et al.  Solution NMR-derived global fold of a monomeric 82-kDa enzyme. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[76]  Jerry Kaplan,et al.  Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization , 2004, Science.

[77]  Mona Singh,et al.  Comparative analysis of methods for representing and searching for transcription factor binding sites , 2004, Bioinform..

[78]  Dana R. Yoerger,et al.  Hydrothermal Prospecting and Petrological Sampling in the Lau Basin: Background Data for the Integrated Study Site , 2004 .

[79]  N. Standen,et al.  Caveolae Localize Protein Kinase A Signaling to Arterial ATP-Sensitive Potassium Channels , 2004, Circulation research.

[80]  Gregory Kucherov,et al.  Improved hit criteria for DNA local alignment , 2004, BMC Bioinformatics.

[81]  Jacky L. Snoep,et al.  Role of Hexose Transport in Control of Glycolytic Flux in Saccharomyces cerevisiae , 2004, Applied and Environmental Microbiology.

[82]  Bin Ma,et al.  Patternhunter Ii: Highly Sensitive and Fast Homology Search , 2004, J. Bioinform. Comput. Biol..

[83]  R. Challiss,et al.  Functional Selectivity of Muscarinic Receptor Antagonists for Inhibition of M3-Mediated Phosphoinositide Responses in Guinea Pig Urinary Bladder and Submandibular Salivary Gland , 2004, Journal of Pharmacology and Experimental Therapeutics.

[84]  G. Kucherov,et al.  Multiseed lossless filtration , 2004, IEEE/ACM Transactions on Computational Biology and Bioinformatics.

[85]  Karl J. Friston,et al.  Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning , 2004, Science.

[86]  M. Chee,et al.  Efficient strategies for the conjugation of oligonucleotides to antibodies enabling highly sensitive protein detection. , 2004, Biopolymers.

[87]  Yusuke Nakamura,et al.  Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection , 2004, Oncogene.

[88]  Colin F. Camerer,et al.  The Economics of Learning Models: A Self-tuning Theory of Learning in Games , 2004 .

[89]  D. Prieur,et al.  Design of 16S rRNA-targeted oligonucleotide probes for detecting cultured and uncultured archaeal lineages in high-temperature environments. , 2004, Environmental microbiology.

[90]  K. Mikoshiba,et al.  L1-dependent neuritogenesis involves ankyrinB that mediates L1-CAM coupling with retrograde actin flow , 2003, The Journal of cell biology.

[91]  Peter G Schultz,et al.  An Expanded Eukaryotic Genetic Code , 2003, Science.

[92]  Alexander E. Kel,et al.  MATCHTM: a tool for searching transcription factor binding sites in DNA sequences , 2003, Nucleic Acids Res..

[93]  Steven Henikoff,et al.  SIFT: predicting amino acid changes that affect protein function , 2003, Nucleic Acids Res..

[94]  Michael Zuker,et al.  Mfold web server for nucleic acid folding and hybridization prediction , 2003, Nucleic Acids Res..

[95]  R Turner,et al.  Optimized EPI for fMRI studies of the orbitofrontal cortex , 2003, NeuroImage.

[96]  Christian Jeanthon,et al.  Archaeal diversity associated with in situ samplers deployed on hydrothermal vents on the East Pacific Rise (13°N) , 2003 .

[97]  B. Birren,et al.  Sequencing and comparison of yeast species to identify genes and regulatory elements , 2003, Nature.

[98]  Yusuke Nakamura,et al.  Expression profiles of non-small cell lung cancers on cDNA microarrays: Identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs , 2003, Oncogene.

[99]  A. Larkum,et al.  Chlorophyll d as the major photopigment in Acaryochloris marina , 2002 .

[100]  E. Boles,et al.  Characterisation of glucose transport in Saccharomyces cerevisiae with plasma membrane vesicles (countertransport) and intact cells (initial uptake) with single Hxt1, Hxt2, Hxt3, Hxt4, Hxt6, Hxt7 or Gal2 transporters. , 2002, FEMS yeast research.

[101]  Alexey I Nesvizhskii,et al.  Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. , 2002, Analytical chemistry.

[102]  F. Speleman,et al.  Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes , 2002, Genome Biology.

[103]  J. Grindlay,et al.  Regulation of the Bfa1p–Bub2p complex at spindle pole bodies by the cell cycle phosphatase Cdc14p , 2002, The Journal of cell biology.

[104]  J. Baross,et al.  Temporal Changes in Archaeal Diversity and Chemistry in a Mid-Ocean Ridge Subseafloor Habitat , 2002, Applied and Environmental Microbiology.

[105]  David Baltimore,et al.  Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors , 2002, Science.

[106]  R. McPherson,et al.  The Low Density Lipoprotein Receptor-related Protein Contributes to Selective Uptake of High Density Lipoprotein Cholesteryl Esters by SW872 Liposarcoma Cells and Primary Human Adipocytes* , 2001, The Journal of Biological Chemistry.

[107]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[108]  K. Horikoshi,et al.  Distribution of Archaea in a Black Smoker Chimney Structure , 2001, Applied and Environmental Microbiology.

[109]  L. Trussell,et al.  Presynaptic glycine receptors enhance transmitter release at a mammalian central synapse , 2001, Nature.

[110]  T. Takagi,et al.  Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia. , 2001, Cancer research.

[111]  A. Plückthun,et al.  Tumor Targeting of Mono-, Di-, and Tetravalent Anti-p185HER-2 Miniantibodies Multimerized by Self-associating Peptides* , 2001, The Journal of Biological Chemistry.

[112]  D. Botstein,et al.  Genomic expression programs in the response of yeast cells to environmental changes. , 2000, Molecular biology of the cell.

[113]  A. Reysenbach,et al.  Novel Bacterial and Archaeal Lineages from an In Situ Growth Chamber Deployed at a Mid-Atlantic Ridge Hydrothermal Vent , 2000, Applied and Environmental Microbiology.

[114]  S W Hell,et al.  EGFP and DsRed expressing cultures of Escherichia coli imaged by confocal, two‐photon and fluorescence lifetime microscopy , 2000, FEBS letters.

[115]  B Sakmann,et al.  Calcium sensitivity of glutamate release in a calyx-type terminal. , 2000, Science.

[116]  M. Kühl,et al.  Bio-optical Characteristics and the Vertical Distribution of Photosynthetic Pigments and Photosynthesis in an Artificial Cyanobacterial Mat , 2000, Microbial Ecology.

[117]  R. Hassett,et al.  Spectroscopic analysis of the trinuclear cluster in the Fet3 protein from yeast, a multinuclear copper oxidase. , 2000, Biochemistry.

[118]  G. Drouin,et al.  Expressed retrotransposed 5S rRNA genes in the mouse and rat genomes. , 2000, Genome.

[119]  W. E. Moerner,et al.  The Fluorescence Dynamics of Single Molecules of Green Fluorescent Protein , 1999 .

[120]  Jerker Widengren,et al.  Protonation kinetics of GFP and FITC investigated by FCS — aspects of the use of fluorescent indicators for measuring pH , 1999 .

[121]  B. Séraphin,et al.  A generic protein purification method for protein complex characterization and proteome exploration , 1999, Nature Biotechnology.

[122]  K. Horikoshi,et al.  Genetic diversity of archaea in deep-sea hydrothermal vent environments. , 1999, Genetics.

[123]  Gary D. Stormo,et al.  Identifying DNA and protein patterns with statistically significant alignments of multiple sequences , 1999, Bioinform..

[124]  Colin Camerer,et al.  Experience‐weighted Attraction Learning in Normal Form Games , 1999 .

[125]  A. Bax,et al.  Protein backbone angle restraints from searching a database for chemical shift and sequence homology , 1999, Journal of biomolecular NMR.

[126]  W. Webb,et al.  Dynamics of fluorescence fluctuations in green fluorescent protein observed by fluorescence correlation spectroscopy. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[127]  E. J. de la Rosa,et al.  Heat shock proteins in retinal neurogenesis: identification of the PM1 antigen as the chick Hsc70 and its expression in comparison to that of other chaperones , 1998, The European journal of neuroscience.

[128]  R J Read,et al.  Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.

[129]  D. Campbell,et al.  Chlorophyll Fluorescence Analysis of Cyanobacterial Photosynthesis and Acclimation , 1998, Microbiology and Molecular Biology Reviews.

[130]  T. Kirchhausen,et al.  The Neural Cell Adhesion Molecule L1 Interacts with the AP-2 Adaptor and Is Endocytosed via the Clathrin-Mediated Pathway , 1998, The Journal of Neuroscience.

[131]  H Clevers,et al.  Two Members of the Tcf Family Implicated in Wnt/β-Catenin Signaling during Embryogenesis in the Mouse , 1998, Molecular and Cellular Biology.

[132]  B Sakmann,et al.  Calcium current during a single action potential in a large presynaptic terminal of the rat brainstem , 1998, The Journal of physiology.

[133]  B. Sakmann,et al.  Calcium dynamics associated with a single action potential in a CNS presynaptic terminal. , 1997, Biophysical journal.

[134]  S. Azhar,et al.  Intracellular Events in the “Selective” Transport of Lipoprotein-derived Cholesteryl Esters* , 1996, The Journal of Biological Chemistry.

[135]  C. Schleper,et al.  Picrophilus gen. nov., fam. nov.: a novel aerobic, heterotrophic, thermoacidophilic genus and family comprising archaea capable of growth around pH 0 , 1995, Journal of bacteriology.

[136]  M. Bols,et al.  Influence of monosaccharide derivatives on liver cell glycosaminoglycan synthesis: 3-deoxy-D-xylo-hexose (3-deoxy-D-galactose) and methyl (methyl 4-chloro-4-deoxy-beta-D-galactopyranosid) uronate. , 1995, Biochimica et biophysica acta.

[137]  A. Goffeau,et al.  An Essential Yeast Gene Encoding a Homolog of Ubiquitin-activating Enzyme (*) , 1995, The Journal of Biological Chemistry.

[138]  R. Hartley,et al.  Directed mutagenesis and barnase-barstar recognition. , 1993, Biochemistry.

[139]  A. Varshavsky,et al.  N-recognin/Ubc2 interactions in the N-end rule pathway. , 1993, The Journal of biological chemistry.

[140]  L. Kaelbling.  Learning in embedded systems , 1993 .

[141]  M. Blaustein,et al.  Ionic currents in rat pulmonary and mesenteric arterial myocytes in primary culture and subculture. , 1993, The American journal of physiology.

[142]  B. Jørgensen,et al.  Spectral light measurements in microbenthic phototrophic communities with a fiber‐optic microprobe coupled to a sensitive diode array detector , 1992 .

[143]  H. Niwa,et al.  Efficient selection for high-expression transfectants with a novel eukaryotic vector. , 1991, Gene.

[144]  K. Kato,et al.  Organization and expression of the chicken N-myc gene , 1990, Molecular and cellular biology.

[145]  R. Sikorski,et al.  A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. , 1989, Genetics.

[146]  K. Stetter,et al.  Thermoplasma acidophilum and Thermoplasma volcanium sp. nov. from Solfatara Fields , 1988 .

[147]  L. Subrahmanyan,et al.  Effects of Culture Substrates and Normal Hepatic Sinusoidal Cells on in Vitro Hepatocyte Synthesis of Apo‐SAA , 1988, Scandinavian journal of immunology.

[148]  J. Rice.  Mathematical Statistics and Data Analysis , 1988 .

[149]  T. D. Schneider,et al.  Information content of binding sites on nucleotide sequences. , 1986, Journal of molecular biology.

[150]  F. J. Friedrich,et al.  Effects of parietal injury on covert orienting of attention , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[151]  W Hörz,et al.  Sequence specific cleavage of DNA by micrococcal nuclease. , 1981, Nucleic acids research.

[152]  R A Laskey,et al.  High sequence specificity of micrococcal nuclease. , 1981, Nucleic acids research.

[153]  G. Schwarz.  Estimating the Dimension of a Model , 1978 .

[154]  D. Rubin,et al.  Maximum likelihood from incomplete data via the EM - algorithm plus discussions on the paper , 1977 .

[155]  B. Brown,et al.  A simple and sensitive saturation assay method for the measurement of adenosine 3':5'-cyclic monophosphate. , 1971, The Biochemical journal.

[156]  T. D. Brock,et al.  A Thermophilic, Acidophilic Mycoplasma Isolated from a Coal Refuse Pile , 1970, Science.

[157]  Leon S. Lasdon,et al.  Optimization Theory of Large Systems , 1970 .

[158]  Joel D. Cline,et al.  SPECTROPHOTOMETRIC DETERMINATION OF HYDROGEN SULFIDE IN NATURAL WATERS1 , 1969 .

[159]  V. Hamburger,et al.  A series of normal stages in the development of the chick embryo , 1951, Journal of morphology.

[160]  István Czachesz,et al.  THE HUMAN BRAIN , 1939, infocus Magazine.

[161]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[162]  S. Henikoff,et al.  Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm , 2009, Nature Protocols.

[163]  T. Beveridge,et al.  Methods for general and molecular microbiology , 2007 .

[164]  Yohey Suzuki,et al.  Geomicrobiological exploration and characterization of a novel deep-sea hydrothermal system at the TOTO caldera in the Mariana Volcanic Arc. , 2006, Environmental microbiology.

[165]  Jing Huang,et al.  Noise Reduction from Genotyping Microarrays Using Probe Level Information , 2006, Silico Biol..

[166]  C. Howe,et al.  Unique origin and lateral transfer of prokaryotic chlorophyll-b and chlorophyll-d light-harvesting systems. , 2005, Molecular biology and evolution.

[167]  BMC Biology , 2004 .

[168]  S. Miyachi,et al.  Functional characteristics of chlorophyll d-predominating photosynthetic apparatus in intact cells of Acaryochloris marina , 2004, Photosynthesis Research.

[169]  Ulrich Schreiber,et al.  Pulse-Amplitude-Modulation (PAM) Fluorometry and Saturation Pulse Method: An Overview , 2004 .

[170]  R. Varga.  Geršgorin And His Circles , 2004 .

[171]  Charles D Schwieters,et al.  The Xplor-NIH NMR molecular structure determination package. , 2003, Journal of magnetic resonance.

[172]  R. Poulsom,et al.  A robust method for isotopic riboprobe in situ hybridisation to localise mRNAs in routine pathology specimens. , 1998, European journal of histochemistry : EJH.

[173]  E. Kremmer,et al.  Specific detection of his-tagged proteins with recombinant anti-His tag scFv-phosphatase or scFv-phage fusions. , 1997, BioTechniques.

[174]  P. Ralph,et al.  Assessment of Photosynthetic Performance of Prochloron in Lissoclinum patella in hospite by Chlorophyll Fluorescence Measurements , 1997 .

[175]  Guoqi Qian,et al.  On model selection in robust linear regression , 1996 .

[176]  A. Plückthun,et al.  Engineered turns of a recombinant antibody improve its in vivo folding. , 1995, Protein engineering.

[177]  A. Raftery,et al.  Bayes factors , 1995 .

[178]  R. Stocker,et al.  Rapid isolation of lipoproteins and assessment of their peroxidation by high-performance liquid chromatography postcolumn chemiluminescence. , 1994, Methods in enzymology.

[179]  Charles Elkan,et al.  Fitting a Mixture Model By Expectation Maximization To Discover Motifs In Biopolymer , 1994, ISMB.

[180]  James J. L'Italien,et al.  Proteins , 1987, Springer US.

[181]  P. Kott.  Algal-bearing didemnid ascidians in the Indo-west-Pacific , 1980 .