Propagation of photon-density waves in strongly scattering media containing an absorbing semi-infinite plane bounded by a straight edge.

Light propagation in strongly scattering media can be described by the diffusion approximation to the Boltzmann transport equation. We have derived analytical expressions based on the diffusion approximation that describe the photon density in a uniform, infinite, strongly scattering medium that contains a sinusoidally intensity-modulated point source of light. These expressions predict that the photon density will propagate outward from the light source as a spherical wave of constant phase velocity with an amplitude that attenuates with distance r from the source as exp(-alpha r)/r. The properties of the photon-density wave are given in terms of the spectral properties of the scattering medium. We have used the Green's function obtained from the diffusion approximation to the Boltzmann transport equation with a sinusoidally modulated point source to derive analytic expressions describing the diffraction and the reflection of photon-density waves from an absorbing and/or reflecting semi-infinite plane bounded by a straight edge immersed in a strongly scattering medium. The analytic expressions given are in agreement with the results of frequency-domain experiments performed in skim-milk media and with Monte Carlo simulations. These studies provide a basis for the understanding of photon diffusion in strongly scattering media in the presence of absorbing and reflecting objects and allow for a determination of the conditions for obtaining maximum resolution and penetration for applications to optical tomography.

[1]  D. Weitz,et al.  Diffusing wave spectroscopy. , 1988, Physical review letters.

[2]  Enrico Gratton,et al.  Digital parallel acquisition in frequency domain fluorimetry , 1989 .

[3]  White,et al.  Probing through cloudiness: Theory of statistical inversion for multiply scattered data. , 1989, Physical review letters.

[4]  A. Sommerfeld Über verzweigte Potentiale im Raum , 1896 .

[5]  B. Wilson,et al.  Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties. , 1989, Applied optics.

[6]  Stephen,et al.  Temporal fluctuations in wave propagation in random media. , 1988, Physical review. B, Condensed matter.

[7]  M W Vannier,et al.  Image reconstruction of the interior of bodies that diffuse radiation. , 1992, Investigative radiology.

[8]  S Nioka,et al.  Time-resolved spectroscopy of hemoglobin and myoglobin in resting and ischemic muscle. , 1988, Analytical biochemistry.

[9]  Beniamino B. Barbieri,et al.  What determines the uncertainty of phase and modulation measurements in frequency-domain fluorometry? , 1990, Photonics West - Lasers and Applications in Science and Engineering.

[10]  A Ishimaru,et al.  Diffusion of light in turbid material. , 1989, Applied optics.

[11]  H. S. Cakslaw Some Multiform Solutions of the Partial Differential Equations of Physical Mathematics and theri Applications , 1898 .

[12]  Robert R. Alfano,et al.  Biological materials probed by the temporal and angular profiles of the backscattered ultrafast laser pulses , 1990 .

[13]  White,et al.  Wave localization characteristics in the time domain. , 1987, Physical review letters.

[14]  Feng,et al.  Theory of speckle-pattern tomography in multiple-scattering media. , 1990, Physical review letters.

[15]  Robert A. Kruger,et al.  Time-of-flight breast imaging system: spatial resolution performance , 1991, Photonics West - Lasers and Applications in Science and Engineering.

[16]  Philip W. Anderson,et al.  The question of classical localization A theory of white paint , 1985 .