Myoepithelial cell‐rich neoplasms: Cytologic features of benign and malignant lesions

Lesions that contain abundant myoepithelial cells may present as a diagnostic challenge in fine‐needle aspiration (FNA) specimens. Potential diagnostic problems may arise due to morphologic heterogeneity of myoepithelial cell‐rich lesions and difficulty in predicting malignancy in FNA specimens. An accurate diagnosis is important, because malignant myoepithelial cell‐rich lesions require a wider local excision and lymph node dissection. The authors characterized the cytologic features of myoepithelial cell‐rich lesions in an attempt to define the criteria that facilitate distinction between benign and malignant tumors.