Two amino acid residues in the matrix protein M1 contribute to the virulence difference of H5N1 avian influenza viruses in mice.

[1]  Guohua Deng,et al.  A Single-Amino-Acid Substitution in the NS1 Protein Changes the Pathogenicity of H5N1 Avian Influenza Viruses in Mice , 2007, Journal of Virology.

[2]  Y. Kawaoka,et al.  Properties and Dissemination of H5N1 Viruses Isolated during an Influenza Outbreak in Migratory Waterfowl in Western China , 2006, Journal of Virology.

[3]  D. Smee,et al.  Mutations in Influenza Virus M1 CCHH, the Putative Zinc Finger Motif, Cause Attenuation in Mice and Protect Mice against Lethal Influenza Virus Infection , 2006, Journal of Virology.

[4]  R. Webster,et al.  Molecular Basis of Replication of Duck H5N1 Influenza Viruses in a Mammalian Mouse Model , 2005, Journal of Virology.

[5]  E. Hoffmann,et al.  A single amino acid change in the C-terminal domain of the matrix protein M1 of influenza B virus confers mouse adaptation and virulence. , 2005, Virology.

[6]  Z. Ye,et al.  Attenuating Mutations of the Matrix Gene of Influenza A/WSN/33 Virus , 2005, Journal of Virology.

[7]  Y Li,et al.  The evolution of H5N1 influenza viruses in ducks in southern China. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[8]  R. Webster,et al.  Lethal H5N1 influenza viruses escape host anti-viral cytokine responses , 2002, Nature Medicine.

[9]  Yoshihiro Kawaoka,et al.  Molecular Basis for High Virulence of Hong Kong H5N1 Influenza A Viruses , 2001, Science.

[10]  Z. Ye,et al.  Effect of influenza virus matrix protein and viral RNA on ribonucleoprotein formation and nuclear export. , 2001, Virology.

[11]  S. Baird,et al.  Pattern of mutation in the genome of influenza A virus on adaptation to increased virulence in the mouse lung: Identification of functional themes , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[12]  W. Weissenhorn,et al.  In vitro dissection of the membrane and RNP binding activities of influenza virus M1 protein. , 2001, Virology.

[13]  E. Govorkova,et al.  Amino acid changes in the hemagglutinin and matrix proteins of influenza a (H2) viruses adapted to mice. , 2000, Acta virologica.

[14]  Z. Ye,et al.  Association of Influenza Virus Matrix Protein with Ribonucleoproteins , 1999, Journal of Virology.

[15]  A. Ward Virulence of Influenza A Virus for Mouse Lung , 1997, Virus Genes.

[16]  F. Baudin,et al.  Influenza virus M1 protein binds to RNA through its nuclear localization signal. , 1997, The Journal of general virology.

[17]  A Helenius,et al.  Effect of M1 protein and low pH on nuclear transport of influenza virus ribonucleoproteins , 1996, Journal of virology.

[18]  A Helenius,et al.  Nuclear trafficking of influenza virus ribonuleoproteins in heterokaryons , 1996, Journal of virology.

[19]  H. Handa,et al.  Mechanism for inhibition of influenza virus RNA polymerase activity by matrix protein , 1996, Journal of virology.

[20]  A Helenius,et al.  Hyperphosphorylation of mutant influenza virus matrix protein, M1, causes its retention in the nucleus , 1995, Journal of virology.

[21]  S. Cusack,et al.  Structure of influenza virus RNP. I. Influenza virus nucleoprotein melts secondary structure in panhandle RNA and exposes the bases to the solvent. , 1994, The EMBO journal.

[22]  E. Brown,et al.  The influenza virus variant A/FM/1/47-MA possesses single amino acid replacements in the hemagglutinin, controlling virulence, and in the matrix protein, controlling virulence as well as growth , 1994, Journal of virology.

[23]  K. Martin,et al.  Nuclear transport of influenza virus ribonucleoproteins: The viral matrix protein (M1) promotes export and inhibits import , 1991, Cell.

[24]  E. Brown,et al.  Increased virulence of a mouse-adapted variant of influenza A/FM/1/47 virus is controlled by mutations in genome segments 4, 5, 7, and 8 , 1990, Journal of virology.

[25]  G. Brownlee,et al.  RNA-binding properties of influenza A virus matrix protein M1. , 1989, Nucleic acids research.

[26]  Z. Ye,et al.  Transcription-inhibition and RNA-binding domains of influenza A virus matrix protein mapped with anti-idiotypic antibodies and synthetic peptides , 1989, Journal of virology.

[27]  A. Reed A left superior vena cava draining the blood from a closed coronary sinus. , 1938, Journal of anatomy.

[28]  K. H. Lee,et al.  Identification and characterization of mutations in the high growth vaccine strain of influenza virus , 2001, Archives of Virology.