and Xenobiotic Metabolism and Utility in Understanding Drug and Human Cytochrome P 450 1 A 1 Structure Protein Structure and Folding
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[1] F. Guengerich,et al. Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes. , 1995, Chemical research in toxicology.
[2] F. Guengerich,et al. Cytochrome P450 activation of arylamines and heterocyclic amines. , 2005, Annual review of pharmacology and toxicology.
[3] Y. Chun,et al. Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin. , 2001, Drug metabolism and disposition: the biological fate of chemicals.
[4] H. Yamazaki,et al. Oxidation of xenobiotics by recombinant human cytochrome P450 1B1. , 1997, Drug metabolism and disposition: the biological fate of chemicals.
[5] G J Kleywegt,et al. Detection, delineation, measurement and display of cavities in macromolecular structures. , 1994, Acta crystallographica. Section D, Biological crystallography.
[6] Eric F. Johnson,et al. Human CYP 2 D 6 Structure 1 CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P 450 2 D 6 WITH PRINOMASTAT BOUND , 2012 .
[7] P. Emsley,et al. Features and development of Coot , 2010, Acta crystallographica. Section D, Biological crystallography.
[8] R. Tukey,et al. Expression of modified human cytochrome P450 1A2 in Escherichia coli: stabilization, purification, spectral characterization, and catalytic activities of the enzyme. , 1994, Archives of biochemistry and biophysics.
[9] M. Varner,et al. In utero tobacco exposure epigenetically modifies placental CYP1A1 expression. , 2010, Metabolism: clinical and experimental.
[10] F. Guengerich,et al. Contributions of human enzymes in carcinogen metabolism. , 2012, Chemical research in toxicology.
[11] M. Burke,et al. Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1. , 2000, Toxicology.
[12] Mark D. Paulsen,et al. Predicting the product specificity and coupling of cytochrome P450cam , 1992, J. Comput. Aided Mol. Des..
[13] W. Kabsch,et al. Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features , 1983, Biopolymers.
[14] Eric F. Johnson,et al. Structural Characterization of the Complex between α-Naphthoflavone and Human Cytochrome P450 1B1* , 2010, The Journal of Biological Chemistry.
[15] T. Shimada,et al. Recombinant human cytochrome P450 1B1 expression in Escherichia coli. , 1998, Archives of biochemistry and biophysics.
[16] K. Battaile,et al. Human Cytochrome P450 2E1 Structures with Fatty Acid Analogs Reveal a Previously Unobserved Binding Mode* , 2010, The Journal of Biological Chemistry.
[17] I. A. D. de Graaf,et al. Induction of Metabolism and Transport in Human Intestine: Validation of Precision-Cut Slices as a Tool to Study Induction of Drug Metabolism in Human Intestine in Vitro , 2008, Drug Metabolism and Disposition.
[18] D. Spandidos,et al. Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention , 2009, BMC Cancer.
[19] C David Stout,et al. Adaptations for the Oxidation of Polycyclic Aromatic Hydrocarbons Exhibited by the Structure of Human P450 1A2*♦ , 2007, Journal of Biological Chemistry.
[20] G. Szklarz,et al. Application of Molecular Modeling for Prediction of Substrate Specificity in Cytochrome P450 1A2 Mutants , 2008, Drug Metabolism and Disposition.
[21] D. Bandyopadhyay,et al. Differential induction of CYP1A1 and CYP1B1 by benzo[a]pyrene in oral squamous cell carcinoma cell lines and by tobacco smoking in oral mucosa. , 2009, Oral oncology.
[22] Spencer S. Ericksen,et al. Preferred Binding Orientations of Phenacetin in CYP1A1 and CYP1A2 Are Associated with Isoform-Selective Metabolism , 2012, Drug Metabolism and Disposition.
[23] Spencer S Ericksen,et al. The effect of reciprocal active site mutations in human cytochromes P450 1A1 and 1A2 on alkoxyresorufin metabolism. , 2004, Archives of biochemistry and biophysics.
[24] W. Delano. The PyMOL Molecular Graphics System , 2002 .
[25] T. Shimada,et al. Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and1B1 , 2004, Cancer science.
[26] Tetsuo Satoh,et al. Tissue distribution of mRNA expression of human cytochrome P450 isoforms assessed by high-sensitivity real-time reverse transcription PCR. , 2003, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
[27] Spencer S. Ericksen,et al. Regiospecificity of Human Cytochrome P450 1A1-Mediated Oxidations: The Role of Steric Effects , 2005, Journal of biomolecular structure & dynamics.
[28] Eric F. Johnson,et al. Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain , 2008, Proceedings of the National Academy of Sciences.
[29] Spencer S Ericksen,et al. Characterization of substrate binding to cytochrome P450 1A1 using molecular modeling and kinetic analyses: case of residue 382. , 2003, Drug metabolism and disposition: the biological fate of chemicals.
[30] Tsutomu Shimada,et al. Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons. , 2006, Drug metabolism and pharmacokinetics.
[31] H. Yamazaki,et al. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1. , 1996, Cancer research.
[32] Spencer S. Ericksen,et al. Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid. , 2004, Biochemical pharmacology.
[33] Shu-Feng Zhou,et al. Insights into the Substrate Specificity, Inhibitors, Regulation, and Polymorphisms and the Clinical Impact of Human Cytochrome P450 1A2 , 2009, The AAPS Journal.
[34] J. Doehmer,et al. Flavonoids inhibit genetic toxicity produced by carcinogens in cells expressing CYP1A2 and CYP1A1. , 2002, Mutagenesis.
[35] G. Lushington,et al. Key Residues Controlling Binding of Diverse Ligands to Human Cytochrome P450 2A Enzymes , 2009, Drug Metabolism and Disposition.
[36] G. Szklarz,et al. Molecular Modeling of Cytochrome P450 1A1: Enzyme-Substrate Interactions and Substrate Binding Affinities , 2002, Journal of biomolecular structure & dynamics.
[37] P. Cooper,et al. Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo , 2003, British Journal of Cancer.
[38] R. Caccavale,et al. Cytochromes P4501 (CYP1): catalytic activities and inducibility by diesel exhaust particle extract and benzo[a]pyrene in intact human lung ex vivo. , 2010, Toxicology.
[39] O. Hankinson. The aryl hydrocarbon receptor complex. , 1995, Annual review of pharmacology and toxicology.
[40] G. Ferron,et al. Quantitation of cytochrome P450 mRNA levels in human skin. , 2003, Analytical biochemistry.
[41] Xiaochao Ma,et al. METABOLISM OF MELATONIN BY HUMAN CYTOCHROMES P450 , 2005, Drug Metabolism and Disposition.
[42] Christus,et al. A General Method Applicable to the Search for Similarities in the Amino Acid Sequence of Two Proteins , 2022 .
[43] G. Murshudov,et al. Refinement of macromolecular structures by the maximum-likelihood method. , 1997, Acta crystallographica. Section D, Biological crystallography.
[44] Significant Increase in Phenacetin Oxidation on L382V Substitution in Human Cytochrome P450 1A2 , 2010, Drug Metabolism and Disposition.
[45] R. Tukey,et al. Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes. , 1997, Carcinogenesis.
[46] L. Loeb,et al. Environmental and chemical carcinogenesis. , 2004, Seminars in cancer biology.
[47] A G Leslie,et al. Biological Crystallography Integration of Macromolecular Diffraction Data , 2022 .
[48] P. Beaune,et al. Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens. , 1992, Molecular pharmacology.
[49] N. Guex,et al. SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling , 1997, Electrophoresis.
[50] Weihua Li,et al. Functional role of residues in the helix B' region of cytochrome P450 2B1. , 2005, Archives of biochemistry and biophysics.
[51] F. Curriero,et al. Expression of cytochromes P450 1A1 and 1B1 in human lung from smokers, non-smokers, and ex-smokers. , 2004, Toxicology and applied pharmacology.
[52] Slobodan Petar Rendic. Summary of information on human CYP enzymes: human P450 metabolism data , 2002, Drug metabolism reviews.
[53] F. Berthou,et al. Involvement of cytochrome P450 1A2 in the biotransformation of trans-resveratrol in human liver microsomes. , 2004, Biochemical pharmacology.
[54] Jaime Pascual,et al. Conformational adaptation of human cytochrome P450 2B6 and rabbit cytochrome P450 2B4 revealed upon binding multiple amlodipine molecules. , 2012, Biochemistry.
[55] F. Guengerich,et al. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2. , 1998, Chemical research in toxicology.
[56] J. Reid,et al. Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.
[57] Collaborative Computational,et al. The CCP4 suite: programs for protein crystallography. , 1994, Acta crystallographica. Section D, Biological crystallography.
[58] F. Guengerich,et al. Resveratrol is a selective human cytochrome P450 1A1 inhibitor. , 1999, Biochemical and biophysical research communications.