Modelling human musculoskeletal functional movements using ultrasound imaging

BackgroundA widespread and fundamental assumption in the health sciences is that muscle functions are related to a wide variety of conditions, for example pain, ischemic and neurological disorder, exercise and injury. It is therefore highly desirable to study musculoskeletal contributions in clinical applications such as the treatment of muscle injuries, post-surgery evaluations, monitoring of progressive degeneration in neuromuscular disorders, and so on.The spatial image resolution in ultrasound systems has improved tremendously in the last few years and nowadays provides detailed information about tissue characteristics. It is now possible to study skeletal muscles in real-time during activity.MethodsThe ultrasound images are transformed to be congruent and are effectively compressed and stacked in order to be analysed with multivariate techniques. The method is applied to a relevant clinical orthopaedic research field, namely to describe the dynamics in the Achilles tendon and the calf during real-time movements.ResultsThis study introduces a novel method to medical applications that can be used to examine ultrasound image sequences and to detect, visualise and quantify skeletal muscle dynamics and functions.ConclusionsThis new objective method is a powerful tool to use when visualising tissue activity and dynamics of musculoskeletal ultrasound registrations.

[1]  E. Simonsen,et al.  A mechanism for increased contractile strength of human pennate muscle in response to strength training: changes in muscle architecture , 2001, The Journal of physiology.

[2]  Stefan Catheline,et al.  Electromechanical delay revisited using very high frame rate ultrasound. , 2009, Journal of applied physiology.

[3]  John A Carrino,et al.  Skeletal muscle imaging and inflammatory myopathies , 2007, Current opinion in rheumatology.

[4]  H. Langberg,et al.  Eccentric exercise in treatment of Achilles tendinopathy , 2006, Scandinavian journal of medicine & science in sports.

[5]  S. Wold,et al.  Principal component analysis of multivariate images , 1989 .

[6]  Karl Pearson F.R.S. LIII. On lines and planes of closest fit to systems of points in space , 1901 .

[7]  Khaled Z. Abd-Elmoniem,et al.  Improved ultrasound speckle motion tracking using nonlinear diffusion filtering , 2001, SPIE Medical Imaging.

[8]  J. Macgregor,et al.  Image texture analysis: methods and comparisons , 2004 .

[9]  M. O'Donnell,et al.  High resolution ultrasound imaging of skeletal muscle dynamics and effects of fatigue , 2004, IEEE Ultrasonics Symposium, 2004.

[10]  Takeo Kanade,et al.  An Iterative Image Registration Technique with an Application to Stereo Vision , 1981, IJCAI.

[11]  W. Grassi,et al.  Musculoskeletal Ultrasound: A State of the Art Review in Rheumatology. Part I: Current Controversies and Issues in the Development of Musculoskeletal Ultrasound in Rheumatology , 2004, Rheumatology.

[12]  Kurt Varmuza,et al.  Multivariate Data Analysis in Chemistry , 2008 .

[13]  J.-Y. Bouguet,et al.  Pyramidal implementation of the lucas kanade feature tracker , 1999 .

[14]  Johan Trygg,et al.  Multivariate analysis of congruent images (MACI) , 2005 .

[15]  Bruce R. Kowalski,et al.  Chemometrics, mathematics and statistics in chemistry , 1984 .

[16]  T Fukunaga,et al.  Nonisometric behavior of fascicles during isometric contractions of a human muscle. , 1998, Journal of applied physiology.

[17]  Paul Geladi,et al.  Some special topics in multivariate image analysis , 1992 .

[18]  Thomas Deffieux,et al.  Ultrafast imaging of in vivo muscle contraction using ultrasound , 2006 .

[19]  L.N. Bohs,et al.  A novel method for angle independent ultrasonic imaging of blood flow and tissue motion , 1991, IEEE Transactions on Biomedical Engineering.

[20]  Eva Kosek,et al.  Decreased muscle blood flow in fibromyalgia patients during standardised muscle exercise: A contrast media enhanced colour doppler study , 2006, European journal of pain.

[21]  P. Sengupta,et al.  Two-dimensional strain--a Doppler-independent ultrasound method for quantitation of regional deformation: validation in vitro and in vivo. , 2005, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[22]  D. Thelen,et al.  Measurement of tendon strain during muscle twitch contractions using ultrasound elastography , 2009, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.

[23]  M. Fink,et al.  Assessment of the mechanical properties of the musculoskeletal system using 2-D and 3-D very high frame rate ultrasound , 2008, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[24]  D Lee,et al.  Musculoskeletal ultrasound. , 2000, Seminars in ultrasound, CT, and MR.

[25]  R. Witte,et al.  Effect of Fatigue on Muscle Elasticity in the Human Forearm Using Ultrasound Strain Imaging , 2006, 2006 International Conference of the IEEE Engineering in Medicine and Biology Society.

[26]  Zvi Vered,et al.  Two-dimensional strain-a novel software for real-time quantitative echocardiographic assessment of myocardial function. , 2004, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[27]  M. O’Donnell,et al.  Strain rate imaging using two-dimensional speckle tracking , 2001, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[28]  Adamantios Arampatzis,et al.  Influence of different shortening velocities preceding stretch on human triceps surae moment generation in vivo. , 2008, Journal of biomechanics.

[29]  Jonas Crosby,et al.  New Noninvasive Method for Assessment of Left Ventricular Rotation: Speckle Tracking Echocardiography , 2005, Circulation.

[30]  Majid Mirmehdi,et al.  Computer vision elastography: speckle adaptive motion estimation for elastography using ultrasound sequences , 2005, IEEE Transactions on Medical Imaging.

[31]  K. Esbensen,et al.  Strategy of multivariate image analysis (MIA) , 1989 .

[32]  J. Todd Book Review: Digital image processing (second edition). By R. C. Gonzalez and P. Wintz, Addison-Wesley, 1987. 503 pp. Price: £29.95. (ISBN 0-201-11026-1) , 1988 .

[33]  Richard G P Lopata,et al.  Performance of two dimensional displacement and strain estimation techniques using a phased array transducer. , 2009, Ultrasound in medicine & biology.