Novel compact architecture for high-resolution sensing with plasmonic gratings in conical mounting

A novel compact architecture implementing grating-coupled surface plasmon resonance (GCSPR) based on polarization modulation in conical mounting is presented. In this system a plasmonic grating is azimuthally rotated in order to support the excitation of high-sensitivity surface plasmon polaritons (SPPs). At SPP resonance, a scan of the incident polarization is performed before and after the binding event and the phase term of the output trend is exploited as sensing parameter. The mechanical complexity of the SPR system is significantly reduced and a resolution down to 10-7 refractive index units is assured. In this work a numerical study of the polarization-based grating-coupled SPR technique is performed and analyzed with Chandezon’s method. Therefore an experimental test on an assembled prototype is presented and applied to the detection of binding events on the grating surface (avidin/biotin reaction, DNA/PNA probes).

[1]  Wolfgang Knoll,et al.  Azimuthal dispersion and energy mode condensation of grating-coupled surface plasmon polaritons , 2008 .

[2]  Lifeng Li,et al.  Multilayer-coated diffraction gratings: differential method of Chandezon et al. revisited , 1994 .

[3]  X. D. Hoa,et al.  Towards integrated and sensitive surface plasmon resonance biosensors: a review of recent progress. , 2007, Biosensors & bioelectronics.

[4]  Denis Habauzit,et al.  SPR-based biosensors: a tool for biodetection of hormonal compounds , 2007, Analytical and bioanalytical chemistry.

[5]  Salvador M. Fernandez,et al.  Grating‐coupled surface plasmon resonance: A cell and protein microarray platform , 2005, Proteomics.

[6]  D. Maystre,et al.  A new theoretical method for diffraction gratings and its numerical application , 1980 .

[7]  Monica Dettin,et al.  Synthesis and Chromatography-Free Purification of PNA-PEO Conjugates for the Functionalisation of Gold Sensors , 2012, Molecules.

[8]  R. McPhedran,et al.  Enhanced SPR sensitivity using periodic metallic structures. , 2007, Optics express.

[9]  Günter Gauglitz,et al.  Surface plasmon resonance sensors: review , 1999 .

[10]  F. Romanato,et al.  Grating-coupled surface plasmon resonance in conical mounting with polarization modulation. , 2012, Optics letters.

[11]  Daniel Maystre,et al.  Multicoated gratings: a differential formalism applicable in the entire optical region , 1982 .

[12]  N. Miura,et al.  Recent advancements in surface plasmon resonance immunosensors for detection of small molecules of biomedical, food and environmental interest , 2007 .

[13]  G. Whitesides,et al.  Fabrication of microfluidic systems in poly(dimethylsiloxane) , 2000, Electrophoresis.

[14]  Ingemar Lundström,et al.  Surface plasmon resonance: instrumental resolution using photo diode arrays , 2000 .

[15]  Gianluca Ruffato,et al.  Near-field numerical analysis of surface plasmon polariton propagation on metallic gratings , 2013 .

[16]  T. Chinowsky,et al.  Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films , 1998 .

[17]  F. Romanato,et al.  Nanoporous gold plasmonic structures for sensing applications. , 2011, Optics express.

[18]  Jiří Homola,et al.  Surface plasmon resonance sensors based on diffraction gratings and prism couplers: sensitivity comparison , 1999 .

[19]  J. Homola.  Surface plasmon resonance based sensors , 2006 .

[20]  S. Maier.  Plasmonics: Fundamentals and Applications , 2007 .

[21]  Mauro Prasciolu,et al.  Interferential lithography of 1D thin metallic sinusoidal gratings: Accurate control of the profile for azimuthal angular dependent plasmonic effects and applications , 2009 .

[22]  Norio Miura,et al.  Continuous flow immunosensor for highly selective and real-time detection of sub-ppb levels of 2-hydroxybiphenyl by using surface plasmon resonance imaging. , 2004, Biosensors & bioelectronics.

[23]  Donghyun Kim,et al.  Grating-based surface plasmon resonance detection of core-shell nanoparticle mediated DNA hybridization. , 2012, Biosensors & bioelectronics.

[24]  David Zbaida,et al.  A single-step photolithographic interface for cell-free gene expression and active biochips. , 2007, Small.

[25]  G Ruffato,et al.  Sensitivity enhancement in grating coupled surface plasmon resonance by azimuthal control. , 2009, Optics express.

[26]  Giovanna Brusatin,et al.  Sinusoidal plasmonic crystals for bio-detection sensors , 2011 .

[27]  Gaetano Granozzi,et al.  Enhanced sensitivity azimuthally controlled grating-coupled surface plasmon resonance applied to the calibration of thiol-poly(ethylene oxide) grafting , 2013 .

[28]  Joshua M. Finkelstein,et al.  Engineering a sustainable future for point-of-care diagnostics and single-use microfluidic devices , 2022, Lab on a chip.

[29]  H. Fujiwara,et al.  Spectroscopic Ellipsometry: Principles and Applications , 2007 .

[30]  Jiří Homola,et al.  Rich information format surface plasmon resonance biosensor based on array of diffraction gratings , 2005 .

[31]  H. Raether.  Surface Plasmons on Smooth and Rough Surfaces and on Gratings , 1988 .

[32]  R. Karlsson,et al.  Surface plasmon resonance detection and multispot sensing for direct monitoring of interactions involving low-molecular-weight analytes and for determination of low affinities. , 1995, Analytical biochemistry.

[33]  Heather Sheardown,et al.  Chemisorption of thiolated poly(ethylene oxide) to gold: surface chain densities measured by ellipsometry and neutron reflectometry. , 2005, Journal of colloid and interface science.

[34]  Olga Telezhnikova,et al.  New approach to spectroscopy of surface plasmons. , 2006, Optics letters.

[35]  Ibrahim Abdulhalim,et al.  Sensitivity‐enhancement methods for surface plasmon sensors , 2011 .

[36]  Volker Scheumann,et al.  Sensitivity studies for specific binding reactions using the biotin/streptavidin system by evanescent optical methods. , 2002, Biosensors & bioelectronics.

[37]  Gianluca Ruffato,et al.  The role of polarization on surface plasmon polariton excitation on metallic gratings in the conical mounting , 2010 .

[38]  S W Hui,et al.  Grafted poly-(ethylene glycol) on lipid surfaces inhibits protein adsorption and cell adhesion. , 1997, Biochimica et biophysica acta.