A REVIEW OF TOXIC EPIDERMAL NECROLYSIS IN BRITAIN

EARLY in 1966 I circulated my colleagues in Britain asking for details of their experience of toxic epidermal necrolysis (T.E.N.) and it is thanks to their generotis response that I am able to summarize the main feattires of 128 cases today, among which are included my four original ones. T.E.N. appears to be a pattern of cutaneous reaction. In 30 cases staphylococcal infection seemed the j^redominant feature, in 36 cases drugs, in 28 cases there co-existed a miscellany of diseases, and in 34 cases there was no cltte as to the cause. Sex.—There was a preponderance of females evident in all groups, of about 3 to 2, (Table I).