Curcumin-Incorporated Biomaterials: In silico and in vitro evaluation of biological potentials

[1]  H. Mirzaei,et al.  Autophagy orchestrates resistance in hepatocellular carcinoma cells. , 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[2]  I. Akbarzadeh,et al.  In silico and in vitro studies of GENT-EDTA encapsulated niosomes: A novel approach to enhance the antibacterial activity and biofilm inhibition in drug-resistant Klebsiella pneumoniae. , 2023, Biomaterials advances.

[3]  K. Subbarao,et al.  Multiple Dipole Source Position and Orientation Estimation Using Non-Invasive EEG-like Signals , 2023, Sensors.

[4]  A. Sahebkar,et al.  The effectiveness of nano‐curcumin on patients with COVID‐19: A systematic review of clinical trials , 2023, Phytotherapy research : PTR.

[5]  Ming L. Wang,et al.  A Rapid Label-Free Disposable Electrochemical Salivary Point-of-Care Sensor for SARS-CoV-2 Detection and Quantification , 2022, Sensors.

[6]  Yuanjin Zhao,et al.  Pt(IV) prodrug initiated microparticles from microfluidics for tumor chemo-, photothermal and photodynamic combination therapy , 2022, Bioactive materials.

[7]  F. Baghbani-Arani,et al.  Evaluation of the cytotoxic effects of silver-zinc oxide nanoparticles synthesized by green method on sw480 cell line , 2022, Emergent Materials.

[8]  N. Abolfathi,et al.  The effect of pore size and layout on mechanical and biological properties of 3D ‐printed bone scaffolds with gradient porosity , 2022, Polymer Composites.

[9]  I. Akbarzadeh,et al.  In vitro Development of Controlled-Release Nanoniosomes for Improved Delivery and Anticancer Activity of Letrozole for Breast Cancer Treatment , 2022, International journal of nanomedicine.

[10]  I. Akbarzadeh,et al.  Engineered UIO-66 metal-organic framework for delivery of curcumin against breast cancer cells: An in vitro evaluation , 2022, Journal of Drug Delivery Science and Technology.

[11]  I. Akbarzadeh,et al.  Cefazolin encapsulated UiO-66-NH2 nanoparticles enhance the antibacterial activity and biofilm inhibition against drug-resistant S. aureus: in vitro and in vivo studies , 2022, Chemical Engineering Journal.

[12]  Yuanjin Zhao,et al.  Photopolymerized 3D Printing Scaffolds with Pt(IV) Prodrug Initiator for Postsurgical Tumor Treatment , 2022, Research.

[13]  M. Naimi-Jamal,et al.  Folate-Targeted Curcumin-Loaded Niosomes for Site-Specific Delivery in Breast Cancer Treatment: In Silico and In Vitro Study , 2022, Molecules.

[14]  M. Mozafari,et al.  Engineered hyaluronic acid-decorated niosomal nanoparticles for controlled and targeted delivery of epirubicin to treat breast cancer , 2022, Materials today. Bio.

[15]  I. Akbarzadeh,et al.  pH-Responsive Chitosan-Adorned Niosome Nanocarriers for Co-Delivery of Drugs for Breast Cancer Therapy , 2022, ACS Applied Nano Materials.

[16]  M. Abdouss,et al.  A novel pH‐responsive nanoniosomal emulsion for sustained release of curcumin from a chitosan‐based nanocarrier: Emphasis on the concurrent improvement of loading, sustained release, and apoptosis induction , 2022, Biotechnology progress.

[17]  Luyang Zhao,et al.  Albumin-mediated “Unlocking” of supramolecular prodrug-like nanozymes toward selective imaging-guided phototherapy , 2022, Chemical science.

[18]  I. Akbarzadeh,et al.  Gingerol/letrozole-loaded mesoporous silica nanoparticles for breast cancer therapy: In-silico and in-vitro studies , 2022, Microporous and Mesoporous Materials.

[19]  Xian Zhou,et al.  Pharmacological considerations for treating neuroinflammation with curcumin in Alzheimer’s disease , 2022, Journal of Neural Transmission.

[20]  B. Abdelazeem,et al.  The effects of curcumin as dietary supplement for patients with COVID-19: A systematic review of randomized clinical trials. , 2022, Drug discoveries & therapeutics.

[21]  F. Sato,et al.  Bioperformance Studies of Biphasic Calcium Phosphate Scaffolds Extracted from Fish Bones Impregnated with Free Curcumin and Complexed with β-Cyclodextrin in Bone Regeneration , 2022, Biomolecules.

[22]  Yang Wang,et al.  The Natural Product Curcumin as an Antibacterial Agent: Current Achievements and Problems , 2022, Antioxidants.

[23]  W. Paul,et al.  Gallium–Curcumin Nanoparticle Conjugates as an Antibacterial Agent against Pseudomonas aeruginosa: Synthesis and Characterization , 2022, ACS omega.

[24]  S. M. Naghib,et al.  A functionalized graphene oxide with improved cytocompatibility for stimuli-responsive co-delivery of curcumin and doxorubicin in cancer treatment , 2022, Scientific reports.

[25]  Adrian L. Lopresti.  Potential Role of Curcumin for the Treatment of Major Depressive Disorder , 2022, CNS Drugs.

[26]  Nguyen Dai Hai,et al.  Enhanced curcumin loaded nanocellulose: a possible inhalable nanotherapeutic to treat COVID-19 , 2022, Cellulose.

[27]  W. Cui,et al.  3D bioprinting of cell-laden constructs for regenerative medicine , 2022, Engineered Regeneration.

[28]  Maciej Banach,et al.  Effectiveness of Curcumin on Outcomes of Hospitalized COVID-19 Patients: A Systematic Review of Clinical Trials , 2022, Nutrients.

[29]  A. Khaledi,et al.  A global systematic review and meta-analysis on correlation between Biofilm producers and Non-biofilm producers with antibiotic resistance in Uropathogenic Escherichiacoli. , 2022, Microbial pathogenesis.

[30]  Bingbing Gao,et al.  Emerging Electrochemical Sensors for Life Healthcare , 2022, Engineered Regeneration.

[31]  J. Quinn,et al.  The Impact of the hAPP695SW Transgene and Associated Amyloid-β Accumulation on Murine Hippocampal Biochemical Pathways. , 2021, Journal of Alzheimer's disease : JAD.

[32]  R. Jose,et al.  Curcumin loaded waste biomass resourced cellulosic nanofiber cloth as a potential scaffold for regenerative medicine: An in-vitro assessment. , 2021, International journal of biological macromolecules.

[33]  G. Venkatasubramanian,et al.  Role of Curcumin in the Management of Schizophrenia: A Narrative Review , 2021, Indian journal of psychological medicine.

[34]  Sajjad Ahmad,et al.  Structural insight into the binding pattern and interaction mechanism of chemotherapeutic agents with Sorcin by docking and molecular dynamic simulation. , 2021, Colloids and surfaces. B, Biointerfaces.

[35]  L. Roshangar,et al.  Synthesis, characterization, and evaluation of curcumin‐loaded endodontic reparative material , 2021, Journal of biochemical and molecular toxicology.

[36]  Long Sheng,et al.  Construction and evaluation of ovalbumin-pullulan nanogels as a potential delivery carrier for curcumin. , 2021, Food chemistry.

[37]  Mulugeta Gajaa,et al.  The impact of curcumin derived polyphenols on the structure and flexibility COVID-19 main protease binding pocket: a molecular dynamics simulation study , 2021, PeerJ.

[38]  Riyan Al Islam Reshad,et al.  In silico investigations on curcuminoids from Curcuma longa as positive regulators of the Wnt/β-catenin signaling pathway in wound healing , 2021, Egyptian Journal of Medical Human Genetics.

[39]  C. Weng,et al.  Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential. , 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[40]  N. Petrovsky,et al.  In silico comparison of SARS-CoV-2 spike protein-ACE2 binding affinities across species and implications for virus origin , 2021, Scientific Reports.

[41]  M. Shahlaei,et al.  Nano drug delivery systems: Molecular dynamic simulation , 2021, Journal of Molecular Liquids.

[42]  Xuefeng Zhou,et al.  Curcumin-Loaded Hybrid Nanoparticles: Microchannel-Based Preparation and Antitumor Activity in a Mouse Model , 2021, International journal of nanomedicine.

[43]  Haixin Jiang,et al.  Construction of carboxymethyl konjac glucomannan/chitosan complex nanogels as potential delivery vehicles for curcumin. , 2021, Food chemistry.

[44]  Meenal V. Kulkarni,et al.  Oral Curcumin With Piperine as Adjuvant Therapy for the Treatment of COVID-19: A Randomized Clinical Trial , 2021, Frontiers in Pharmacology.

[45]  Ahmad B. Albadarin,et al.  Investigations of adsorption behavior and anti-cancer activity of curcumin on pure and platinum-functionalized B12N12 nanocages , 2021, Journal of Molecular Liquids.

[46]  M. Moraveji,et al.  In‐Silico Tuning of Curcumin Loading on PEG Grafted Chitosan: An Atomistic Simulation , 2021 .

[47]  S. Debnath,et al.  Mushrooms are potential foods against cancer: identified by molecular docking and molecular dynamics simulation , 2021, Natural product research.

[48]  A. Kulkarni,et al.  Thermoresponsive Pluronic based microgels for controlled release of curcumin against breast cancer cell line. , 2021, Colloids and surfaces. B, Biointerfaces.

[49]  P. Dubey,et al.  Molecular Docking and Molecular Dynamics Simulation Studies of Quinoline-3-Carboxamide Derivatives with DDR Kinases–Selectivity Studies towards ATM Kinase , 2021, Chemistry.

[50]  E. Egito,et al.  Will curcumin nanosystems be the next promising antiviral alternatives in COVID-19 treatment trials? , 2021, Biomedicine & Pharmacotherapy.

[51]  Z. Batool,et al.  Production of self-assembling acylated ovalbumin nanogels as stable delivery vehicles for curcumin. , 2021, Food chemistry.

[52]  S. Bahmanyar,et al.  The challenges of generalizability in artificial intelligence for ADME/Tox endpoint and activity prediction , 2021, Expert opinion on drug discovery.

[53]  J. Tavis,et al.  Synthetic Derivatives of Ciclopirox are Effective Inhibitors of Cryptococcus neoformans , 2021, ACS omega.

[54]  V. Thakur,et al.  Synthesis of Curcumin Loaded Smart pH-Responsive Stealth Liposome as a Novel Nanocarrier for Cancer Treatment , 2021, Fibers.

[55]  A. Bordbar,et al.  Molecular dynamics simulation study of curcumin interaction with nano-micelle of PNIPAAm-b-PEG co-polymer as a smart efficient drug delivery system , 2021 .

[56]  C. García,et al.  Antiviral activity against Zika virus of a new formulation of curcumin in poly lactic-co-glycolic acid nanoparticles. , 2021, The Journal of pharmacy and pharmacology.

[57]  T. Casalini.  Not only in silico drug discovery: Molecular modeling towards in silico drug delivery formulations. , 2021, Journal of controlled release : official journal of the Controlled Release Society.

[58]  S. Fu,et al.  Therapeutic effects of EGF-modified curcumin/chitosan nano-spray on wound healing , 2021, Regenerative biomaterials.

[59]  Shyi-Long Lee,et al.  Highly selective detection of isatin using curcumin analogue and its application in real samples , 2021 .

[60]  A. Jemal,et al.  Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries , 2021, CA: a cancer journal for clinicians.

[61]  Anoop Kumar,et al.  HeroMDAnalysis: an automagical tool for GROMACS-based molecular dynamics simulation analysis. , 2021, Future medicinal chemistry.

[62]  K. Ahmed,et al.  Curcumin: reclaiming the lost ground against cancer resistance , 2021, Cancer drug resistance.

[63]  A. B. Jena,et al.  Catechin and curcumin interact with S protein of SARS-CoV2 and ACE2 of human cell membrane: insights from computational studies , 2021, Scientific reports.

[64]  G. Zhai,et al.  Galactosamine-modified PEG-PLA/TPGS micelles for the oral delivery of curcumin. , 2021, International journal of pharmaceutics.

[65]  I. Akbarzadeh,et al.  Smart Materials in Regenerative Medicine , 2021, Modern Medical Laboratory Journal.

[66]  C. Yeh,et al.  Gelatin scaffold with multifunctional curcumin-loaded lipid-PLGA hybrid microparticles for regenerating corneal endothelium. , 2021, Materials science & engineering. C, Materials for biological applications.

[67]  Pahweenvaj Ratnatilaka Na Bhuket,et al.  Self-Assembled Thermoresponsive Nanogel from Grafted Hyaluronic Acid as a Biocompatible Delivery Platform for Curcumin with Enhanced Drug Loading and Biological Activities , 2021, Polymers.

[68]  Guang-hong Zhou,et al.  Forming nanoconjugates or inducing macroaggregates, curcumin dose effect on myosin assembling revealed by molecular dynamics simulation , 2020 .

[69]  Mohammed S. Alqahtani,et al.  Wound-healing potential of curcumin loaded lignin nanoparticles , 2020 .

[70]  Ya Zhang,et al.  Targeting the Wnt/β-catenin signaling pathway in cancer , 2020, Journal of Hematology & Oncology.

[71]  A. H. Hassan,et al.  Development of Provesicular Nanodelivery System of Curcumin as a Safe and Effective Antiviral Agent: Statistical Optimization, In Vitro Characterization, and Antiviral Effectiveness , 2020, Molecules.

[72]  Solmaz Maleki Dizaj,et al.  Curcumin Nanocrystals: Production, Physicochemical Assessment, and In Vitro Evaluation of the Antimicrobial Effects against Bacterial Loading of the Implant Fixture , 2020, Applied Sciences.

[73]  N. Jadhav,et al.  Novel curcumin ascorbic acid cocrystal for improved solubility , 2020, Journal of Drug Delivery Science and Technology.

[74]  M. Dalamaga,et al.  The combination of bromelain and curcumin as an immune-boosting nutraceutical in the prevention of severe COVID-19 , 2020, Metabolism Open.

[75]  R. Parks,et al.  Curcumin as an Antiviral Agent , 2020, Viruses.

[76]  Taj Mohammad,et al.  InstaDock: A single-click graphical user interface for molecular docking-based virtual high-throughput screening , 2020, Briefings Bioinform..

[77]  Solmaz Maleki Dizaj,et al.  Nanofibrous asymmetric collagen/curcumin membrane containing aspirin-loaded PLGA nanoparticles for guided bone regeneration , 2020, Scientific Reports.

[78]  F. Huyop,et al.  Molecular docking and molecular dynamics simulation of Bacillus thuringiensis dehalogenase against haloacids, haloacetates and chlorpyrifos , 2020, Journal of biomolecular structure & dynamics.

[79]  A. Belfaitah,et al.  Design, synthesis, biological evaluation, molecular docking, DFT calculations and in silico ADME analysis of (benz)imidazole-hydrazone derivatives as promising antioxidant, antifungal, and anti-acetylcholinesterase agents , 2020, Journal of Molecular Structure.

[80]  Seyed Jamal Tabatabaei Rezaei,et al.  pH-sensitive curcumin conjugated micelles for tumor triggered drug delivery , 2020, Journal of biomaterials science. Polymer edition.

[81]  S. Alven,et al.  Polymer-Based Materials Loaded with Curcumin for Wound Healing Applications , 2020, Polymers.

[82]  A. Safitri,et al.  Metabolomic Profiles of Curcuma longa L and Cosmos caudatus Extracts and Their In-Silico Anti-cancer Activity , 2020, Journal of Physics: Conference Series.

[83]  V. Aswal,et al.  Structural and therapeutic properties of curcumin solubilized pluronic F127 micellar solutions and hydrogels , 2020, Journal of Molecular Liquids.

[84]  Navaneet Chaturvedi,et al.  Curcumin, a traditional spice component, can hold the promise against COVID-19? , 2020, European Journal of Pharmacology.

[85]  M. Nosrati,et al.  Synergistic Effect of Self-Assembled Curcumin and Piperine Co-Loaded Human Serum Albumin Nanoparticles on Suppressing Cancer Cells , 2020, Drug development and industrial pharmacy.

[86]  Pradeep Kumar Mishra,et al.  Nano-fibrous scaffold with curcumin for anti-scar wound healing. , 2020, International journal of pharmaceutics.

[87]  H. Hosseinzadeh,et al.  Curcumin (a constituent of turmeric): New treatment option against COVID‐19 , 2020, Food science & nutrition.

[88]  I. Doytchinova,et al.  Curcumin Inhibits the Primary Nucleation of Amyloid-Beta Peptide: A Molecular Dynamics Study , 2020, Biomolecules.

[89]  A. Silva,et al.  Polymeric Nanoparticles: Production, Characterization, Toxicology and Ecotoxicology , 2020, Molecules.

[90]  K. Thai,et al.  Design of Curcumin and Flavonoid Derivatives with Acetylcholinesterase and Beta-Secretase Inhibitory Activities Using in Silico Approaches , 2020, Molecules.

[91]  A. Haider,et al.  Design, Construction and Characterization of Intelligence Polymer Coated Core–Shell Nanocarrier for Curcumin Drug Encapsulation and Delivery in Lung Cancer Therapy Purposes , 2020, Journal of Inorganic and Organometallic Polymers and Materials.

[92]  Ankit Jain,et al.  Systematic development and characterization of curcumin-loaded nanogel for topical application , 2020, Drug development and industrial pharmacy.

[93]  L. Lim,et al.  Curcumin-loaded electrospun nonwoven as a colorimetric indicator for volatile amines , 2020 .

[94]  Dalal A Abou el-Ella,et al.  Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents. , 2020, Bioorganic chemistry.

[95]  Shuguang Yuan,et al.  Discovering Anti-Cancer Drugs via Computational Methods , 2020, Frontiers in Pharmacology.

[96]  F. Fahma,et al.  The potential of bioactives as biosensors for detection of pH , 2020, IOP Conference Series: Earth and Environmental Science.

[97]  Bhumi M. Shah,et al.  In silico studies on therapeutic agents for COVID-19: Drug repurposing approach , 2020, Life Sciences.

[98]  S. Mousa,et al.  Antiviral Activity of Chitosan Nanoparticles Encapsulating Curcumin Against Hepatitis C Virus Genotype 4a in Human Hepatoma Cell Lines , 2020, International journal of nanomedicine.

[99]  Guang-hong Zhou,et al.  Molecular dynamics simulation exploration of the interaction between curcumin and myosin combined with the results of spectroscopy techniques , 2020 .

[100]  F. Fahma,et al.  Potentiality of ethanol curcumin extract as biosensor for detection of sodium tetraborate , 2020, IOP Conference Series: Earth and Environmental Science.

[101]  V. Zucolotto,et al.  Applications of biosensors in Alzheimer's disease diagnosis. , 2020, Talanta.

[102]  S. Sampathi,et al.  "Nanogels as drug Carriers- Introduction, chemical Aspects, release mechanisms and potential Applications". , 2020, International journal of pharmaceutics.

[103]  Bishajit Sarkar,et al.  Curcumin analogs as the inhibitors of TLR4 pathway in inflammation and their drug like potentialities: a computer-based study , 2020, Journal of receptor and signal transduction research.

[104]  A. K. Kondapi,et al.  Sulfonate modified Lactoferrin nanoparticles as drug carriers with dual activity against HIV-1. , 2020, Colloids and surfaces. B, Biointerfaces.

[105]  R. Mohammadinejad,et al.  Potential therapeutic effects of curcumin mediated by JAK/STAT signaling pathway: A review. , 2020, Phytotherapy research : PTR.

[106]  Myrianthi Hadjicharalambous,et al.  From tumour perfusion to drug delivery and clinical translation of in silico cancer models. , 2020, Methods.

[107]  D. Na.  User guides for biologists to learn computational methods , 2020, Journal of Microbiology.

[108]  Dhaval B. Patel,et al.  Synthesis of novel quinoline‐thiosemicarbazide hybrids and evaluation of their biological activities, molecular docking, molecular dynamics, pharmacophore model studies, and ADME‐Tox properties , 2020 .

[109]  S. Ghannay,et al.  Synthesis, in vitro antimicrobial assessment, and computational investigation of pharmacokinetic and bioactivity properties of novel trifluoromethylated compounds using in silico ADME and toxicity prediction tools , 2020, Monatshefte für Chemie - Chemical Monthly.

[110]  G. Sethi,et al.  Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review , 2020, Molecules.

[111]  Md. Fakhrul Islam,et al.  Controlled release of curcumin from electrospun fiber mats with antibacterial activity , 2020 .

[112]  Zhipeng Gu,et al.  Advances and Impact of Antioxidant Hydrogel in Chronic Wound Healing , 2020, Advanced healthcare materials.

[113]  Sun-Young Lee,et al.  Curcumin incorporation into an oxidized cellulose nanofiber-polyvinyl alcohol hydrogel system promotes wound healing , 2020 .

[114]  R. Chandra,et al.  Chloro and bromo-pyrazole curcumin Knoevenagel condensates augmented anticancer activity against human cervical cancer cells: design, synthesis, in silico docking and in vitro cytotoxicity analysis , 2020, Journal of biomolecular structure & dynamics.

[115]  D. Ma,et al.  Supramolecular hydrogel containing multi-generation poly(L-lysine) dendrons for sustained co-delivery of docetaxel and matrix metallopeptidase-9 short hairpin RNA plasmid , 2020 .

[116]  R. Hosseinzadeh,et al.  Antimicrobial photodynamic and wound healing activity of curcumin encapsulated in silica nanoparticles. , 2019, Photodiagnosis and photodynamic therapy.

[117]  M. Sadeghizadeh,et al.  Investigating curcumin potential for diabetes cell therapy, in vitro and in vivo study. , 2019, Life sciences.

[118]  Mengting Teng,et al.  Enhanced curcumin solubility and antibacterial activity by encapsulation in PLGA oily core nanocapsules. , 2019, Food & function.

[119]  Phanourios Tamamis,et al.  Interactions between Curcumin Derivatives and Amyloid-β Fibrils: Insights from Molecular Dynamics Simulations , 2019, J. Chem. Inf. Model..

[120]  J. Rosenholm,et al.  Nanogels as drug delivery systems: a comprehensive overview. , 2019, Therapeutic delivery.

[121]  I. Nabipour,et al.  Encapsulation of curcumin loaded chitosan nanoparticle within poly (ε-caprolactone) and gelatin fiber mat for wound healing and layered dermal reconstitution. , 2019, International journal of biological macromolecules.

[122]  Jining Li,et al.  Photo active control of plasmon-induced reflection in complementary terahertz metamaterials , 2019, SPIE/COS Photonics Asia.

[123]  N. Škalko-Basnet,et al.  Liposomes augment biological benefits of curcumin for multitargeted skin therapy. , 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[124]  Wei‐Chien Huang,et al.  Effects of Bilayer Nanofibrous Scaffolds Containing Curcumin/Lithospermi Radix Extract on Wound Healing in Streptozotocin-Induced Diabetic Rats , 2019, Polymers.

[125]  Yifan Zhang,et al.  Liposome co-encapsulation as a strategy for the delivery of curcumin and resveratrol. , 2019, Food & function.

[126]  A. Kairytė,et al.  Curcumin as a natural compound in the synthesis of rigid polyurethane foams with enhanced mechanical, antibacterial and anti-ageing properties , 2019, Polymer Testing.

[127]  P. Balashanmugam,et al.  Enhanced wound healing by PVA/Chitosan/Curcumin patches: In vitro and in vivo study. , 2019, Colloids and surfaces. B, Biointerfaces.

[128]  M. Rezayi,et al.  The role of curcumin and its derivatives in sensory applications. , 2019, Materials science & engineering. C, Materials for biological applications.

[129]  A. Giordano,et al.  Curcumin and Cancer , 2019, Nutrients.

[130]  Zhengzong Wu,et al.  Fabrication of chitosan hydrochloride and carboxymethyl starch complex nanogels as potential delivery vehicles for curcumin. , 2019, Food chemistry.

[131]  Xi Zheng,et al.  Molecular Interactions for the Curcumin-Polymer Complex with Enhanced Anti-Inflammatory Effects , 2019, Pharmaceutics.

[132]  M. Soleimani,et al.  Biological behavior of the curcumin incorporated chitosan/poly(vinyl alcohol) nanofibers for biomedical applications , 2019, Journal of cellular biochemistry.

[133]  M. Iqbal,et al.  Wound healing potential of curcumin cross-linked chitosan/polyvinyl alcohol. , 2019, International journal of biological macromolecules.

[134]  S. Mahajan,et al.  Multifunctional mesoporous curcumin encapsulated iron-phenanthroline nanocluster: A new Anti-HIV agent. , 2019, Colloids and surfaces. B, Biointerfaces.

[135]  J. Pandey,et al.  Novel binary grafted chitosan nanocarrier for sustained release of curcumin. , 2019, International journal of biological macromolecules.

[136]  Heyou Han,et al.  Synergistic antibacterial effects of curcumin modified silver nanoparticles through ROS-mediated pathways. , 2019, Materials science & engineering. C, Materials for biological applications.

[137]  Peifeng Li,et al.  Potential Mechanisms of Action of Curcumin for Cancer Prevention: Focus on Cellular Signaling Pathways and miRNAs , 2019, International journal of biological sciences.

[138]  Kunn Hadinoto,et al.  A simple strategy to enhance the in vivo wound-healing activity of curcumin in the form of self-assembled nanoparticle complex of curcumin and oligochitosan. , 2019, Materials science & engineering. C, Materials for biological applications.

[139]  T. Webster,et al.  The effect of chrysin–curcumin-loaded nanofibres on the wound-healing process in male rats , 2019, Artificial cells, nanomedicine, and biotechnology.

[140]  Jie Cai,et al.  Maillard-Reacted Whey Protein Isolates and Epigallocatechin Gallate Complex Enhance the Thermal Stability of the Pickering Emulsion Delivery of Curcumin. , 2019, Journal of agricultural and food chemistry.

[141]  D. Mcclements,et al.  Fabrication and Characterization of Layer-by-Layer Composite Nanoparticles Based on Zein and Hyaluronic Acid for Codelivery of Curcumin and Quercetagetin. , 2019, ACS applied materials & interfaces.

[142]  A. Maugeri,et al.  Nutrition and Wound Healing: An Overview Focusing on the Beneficial Effects of Curcumin , 2019, International journal of molecular sciences.

[143]  Mhd Anas Tomeh,et al.  A Review of Curcumin and Its Derivatives as Anticancer Agents , 2019, International journal of molecular sciences.

[144]  Satyendra Mishra,et al.  Recent Updates in Curcumin Pyrazole and Isoxazole Derivatives: Synthesis and Biological Application , 2019, Chemistry & biodiversity.

[145]  C. Leong,et al.  An Evaluation of Curcumin-Encapsulated Chitosan Nanoparticles for Transdermal Delivery , 2019, AAPS PharmSciTech.

[146]  R. Zhang,et al.  Fabrication of Stable and Self-Assembling Rapeseed Protein Nanogel for Hydrophobic Curcumin Delivery. , 2019, Journal of agricultural and food chemistry.

[147]  B. Ly,et al.  Nanogels of acetylated ulvan enhance the solubility of hydrophobic drug curcumin , 2019, Bulletin of Materials Science.

[148]  G. Ferns,et al.  Curcumin in tissue engineering: A traditional remedy for modern medicine , 2018, BioFactors.

[149]  Noureddine Raouafi,et al.  Curcumin-graphene quantum dots for dual mode sensing platform: Electrochemical and fluorescence detection of APOe4, responsible of Alzheimer's disease. , 2018, Analytica chimica acta.

[150]  Lei Dai,et al.  Effect of molecular weight of hyaluronan on zein-based nanoparticles: Fabrication, structural characterization and delivery of curcumin. , 2018, Carbohydrate polymers.

[151]  Janez Konc,et al.  Inverse Molecular Docking as a Novel Approach to Study Anticarcinogenic and Anti-Neuroinflammatory Effects of Curcumin , 2018, Molecules.

[152]  Yanbin Li,et al.  An enzyme-free biosensor for sensitive detection of Salmonella using curcumin as signal reporter and click chemistry for signal amplification , 2018, Theranostics.

[153]  Youngkwan Lee,et al.  Curcumin-based electrochemical sensor of amyloid-β oligomer for the early detection of Alzheimer’s disease , 2018, Sensors and Actuators B: Chemical.

[154]  Wei Li,et al.  Magnetic Alginate/Chitosan Nanoparticles for Targeted Delivery of Curcumin into Human Breast Cancer Cells , 2018, Nanomaterials.

[155]  Zhiqiang Yu,et al.  Rational design of multi-stimuli-responsive gold nanorod-curcumin conjugates for chemo-photothermal synergistic cancer therapy. , 2018, Biomaterials science.

[156]  Devasena Thiyagarajan,et al.  Carboxymethyl cellulose-functionalised magnetic nanocarriers for pH responsive delivery of Curcumin in cancer therapy , 2018, Materials Research Express.

[157]  Sekhar Babu Mitta,et al.  Metallo-Curcumin-Conjugated DNA Complexes Induces Preferential Prostate Cancer Cells Cytotoxicity and Pause Growth of Bacterial Cells , 2018, Scientific Reports.

[158]  B. Aggarwal,et al.  Inflammation, a Double-Edge Sword for Cancer and Other Age-Related Diseases , 2018, Front. Immunol..

[159]  M. de Perrot,et al.  Curcumin induces apoptosis and inhibits angiogenesis in murine malignant mesothelioma , 2018, International journal of oncology.

[160]  Leonardo Fernandes Fraceto,et al.  Nano based drug delivery systems: recent developments and future prospects , 2018, Journal of Nanobiotechnology.

[161]  Tanya Marchant,et al.  High-quality health systems in the Sustainable Development Goals era: time for a revolution , 2018, The Lancet. Global health.

[162]  Junmei Wang,et al.  An insight into paracetamol and its metabolites using molecular docking and molecular dynamics simulation , 2018, Journal of Molecular Modeling.

[163]  S. Davaran,et al.  Production of biological nanoparticles from bovine serum albumin as controlled release carrier for curcumin delivery. , 2018, International journal of biological macromolecules.

[164]  H. Rashedi,et al.  Molecular dynamic of curcumin/chitosan interaction using a computational molecular approach: Emphasis on biofilm reduction. , 2018, International journal of biological macromolecules.

[165]  Kazunori Kataoka,et al.  Block Copolymer Micelles in Nanomedicine Applications. , 2018, Chemical reviews.

[166]  Ming-Jer Tang,et al.  Mechanical forces in skin disorders. , 2018, Journal of dermatological science.

[167]  Liqiang Zou,et al.  Pluronics modified liposomes for curcumin encapsulation: Sustained release, stability and bioaccessibility. , 2018, Food research international.

[168]  N. Eslahi,et al.  Dual-Sensitive Hydrogel Nanoparticles Based on Conjugated Thermoresponsive Copolymers and Protein Filaments for Triggerable Drug Delivery. , 2018, ACS applied materials & interfaces.

[169]  Y. S. Negi,et al.  pH-responsive prodrug nanoparticles based on xylan-curcumin conjugate for the efficient delivery of curcumin in cancer therapy. , 2018, Carbohydrate polymers.

[170]  Shijie Cao,et al.  Biological and pharmacological effects of hexahydrocurcumin, a metabolite of curcumin. , 2018, Archives of biochemistry and biophysics.

[171]  Do-Hee Kim,et al.  Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells , 2018, Scientific Reports.

[172]  S. Yeh,et al.  Androgen receptor (AR) degradation enhancer ASC-J9® in an FDA-approved formulated solution suppresses castration resistant prostate cancer cell growth. , 2018, Cancer letters.

[173]  V. Padmini,et al.  Synthesis and characterization of curcumin-sulfonamide hybrids: Biological evaluation and molecular docking studies , 2018 .

[174]  I. Haririan,et al.  Curcumin‐lipoic acid conjugate as a promising anticancer agent on the surface of gold‐iron oxide nanocomposites: A pH‐sensitive targeted drug delivery system for brain cancer theranostics , 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[175]  Chibuike C. Udenigwe,et al.  Polyelectrolyte Complex Nanoparticles from Chitosan and Acylated Rapeseed Cruciferin Protein for Curcumin Delivery. , 2018, Journal of agricultural and food chemistry.

[176]  A. Chakraborty,et al.  Enhancement of anticancer activity and drug delivery of chitosan-curcumin nanoparticle via molecular docking and simulation analysis. , 2018, Carbohydrate polymers.

[177]  John Yu,et al.  Structure-based design for binding peptides in anti-cancer therapy. , 2018, Biomaterials.

[178]  U. Dwivedi,et al.  Modulation in the conformational and stability attributes of the Alzheimer’s disease associated amyloid-beta mutants and their favorable stabilization by curcumin: molecular dynamics simulation analysis , 2018, Journal of biomolecular structure & dynamics.

[179]  Ying-zheng Zhao,et al.  pH-sensitive polymeric nanoparticles of mPEG-PLGA-PGlu with hybrid core for simultaneous encapsulation of curcumin and doxorubicin to kill the heterogeneous tumour cells in breast cancer , 2018, Artificial cells, nanomedicine, and biotechnology.

[180]  S. Teimourian,et al.  Delivery of curcumin by a pH-responsive chitosan mesoporous silica nanoparticles for cancer treatment , 2018, Artificial cells, nanomedicine, and biotechnology.

[181]  H. Chun,et al.  Preparation of poly-l-lysine-based nanoparticles with pH-sensitive release of curcumin for targeted imaging and therapy of liver cancer in vitro and in vivo , 2018, Drug delivery.

[182]  V. Kutala,et al.  Mitochondrial targeted curcumin exhibits anticancer effects through disruption of mitochondrial redox and modulation of TrxR2 activity , 2017, Free radical biology & medicine.

[183]  S. Ramakrishna,et al.  Collagen‐cellulose nanocrystal scaffolds containing curcumin‐loaded microspheres on infected full‐thickness burns repair , 2017, Journal of tissue engineering and regenerative medicine.

[184]  H. D. Pranowo,et al.  Molecular docking analysis of curcumin analogues with COX-2 , 2017, Bioinformation.

[185]  H. Manjunatha,et al.  Molecular docking analysis of curcumin analogues against kinase domain of ALK5 , 2017, In Silico Pharmacology.

[186]  Ghrifi Fatima,et al.  In Silico Inhibition Studies of AXL Kinase by Curcumin and its Natural Derivatives , 2017 .

[187]  J. Grutzendler,et al.  Oxalate-curcumin–based probe for micro- and macroimaging of reactive oxygen species in Alzheimer’s disease , 2017, Proceedings of the National Academy of Sciences.

[188]  Rakesh K. Sharma,et al.  Immunomodulatory activities of curcumin-stabilized silver nanoparticles: Efficacy as an antiretroviral therapeutic , 2017, Immunological investigations.

[189]  A. López-Rubio,et al.  Microencapsulation structures based on protein-coated liposomes obtained through electrospraying for the stabilization and improved bioaccessibility of curcumin. , 2017, Food chemistry.

[190]  Saeed Alqahtani,et al.  In silico ADME-Tox modeling: progress and prospects , 2017, Expert opinion on drug metabolism & toxicology.

[191]  C. Mohanty,et al.  Curcumin and its topical formulations for wound healing applications. , 2017, Drug discovery today.

[192]  G. Khang,et al.  Bioengineered porous composite curcumin/silk scaffolds for cartilage regeneration. , 2017, Materials science & engineering. C, Materials for biological applications.

[193]  A. Boddy,et al.  Curcumin as a clinically-promising anti-cancer agent: pharmacokinetics and drug interactions , 2017, Expert opinion on drug metabolism & toxicology.

[194]  Yitao Wang,et al.  pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities. , 2017, Acta biomaterialia.

[195]  B. Aggarwal,et al.  Curcumin mediates anticancer effects by modulating multiple cell signaling pathways. , 2017, Clinical science.

[196]  N. Othman,et al.  Curcumin: the spicy modulator of breast carcinogenesis , 2017, Journal of experimental & clinical cancer research : CR.

[197]  Ronghui Wang,et al.  Self-Assembly of Protein Nanoparticles from Rice Bran Waste and Their Use as Delivery System for Curcumin , 2017 .

[198]  C. Pedone,et al.  Curcumin and Lung Cancer: the Role of microRNAs. , 2017, Current pharmaceutical design.

[199]  D. Das,et al.  Investigation on a smart nanocarrier with a mesoporous magnetic core and thermo-responsive shell for co-delivery of doxorubicin and curcumin: a new approach towards combination therapy of cancer , 2017 .

[200]  Khalid Saeed,et al.  Nanoparticles: Properties, applications and toxicities , 2017, Arabian Journal of Chemistry.

[201]  C. Biggs,et al.  Magnetic-Silk Core-Shell Nanoparticles as Potential Carriers for Targeted Delivery of Curcumin into Human Breast Cancer Cells. , 2017, ACS biomaterials science & engineering.

[202]  Yongqiang Hou,et al.  Anticancer effect of curcumin inhibits cell growth through miR-21/PTEN/Akt pathway in breast cancer cell , 2017, Oncology letters.

[203]  A. Schilling,et al.  Nano-formulated curcumin accelerates acute wound healing through Dkk-1-mediated fibroblast mobilization and MCP-1-mediated anti-inflammation , 2017 .

[204]  Liu Junbo,et al.  Preparation and properties evaluation of a novel pH-sensitive liposomes based on imidazole-modified cholesterol derivatives. , 2017, International journal of pharmaceutics.

[205]  H. Thu,et al.  Nanoencapsulation, an efficient and promising approach to maximize wound healing efficacy of curcumin: A review of new trends and state-of-the-art. , 2017, Colloids and surfaces. B, Biointerfaces.

[206]  Hong Sun,et al.  Co-delivery of doxorubicin and pH-sensitive curcumin prodrug by transferrin-targeted nanoparticles for breast cancer treatment. , 2017, Oncology reports.

[207]  R. Larson,et al.  Assessing the Efficacy of Poly(N-isopropylacrylamide) for Drug Delivery Applications Using Molecular Dynamics Simulations. , 2017, Molecular pharmaceutics.

[208]  P. Kumaradhas,et al.  Understanding the conformational flexibility and electrostatic properties of curcumin in the active site of rhAChE via molecular docking, molecular dynamics, and charge density analysis , 2017, Journal of biomolecular structure & dynamics.

[209]  Gowthamarajan Kuppusamy,et al.  Curcumin loaded chitosan nanoparticles impregnated into collagen-alginate scaffolds for diabetic wound healing. , 2016, International journal of biological macromolecules.

[210]  Shan-shan Wu,et al.  Improved bioavailability of curcumin in ovalbumin-dextran nanogels prepared by Maillard reaction , 2016 .

[211]  Deepa K. Raj,et al.  Preparation, characterization and biological evaluation of curcumin loaded alginate aldehyde-gelatin nanogels. , 2016, Materials science & engineering. C, Materials for biological applications.

[212]  Chunyan Dong,et al.  Novel curcumin-loaded human serum albumin nanoparticles surface functionalized with folate: characterization and in vitro/vivo evaluation , 2016, Drug design, development and therapy.

[213]  W. Lu,et al.  Curcumin inhibited HGF-induced EMT and angiogenesis through regulating c-Met dependent PI3K/Akt/mTOR signaling pathways in lung cancer , 2016, Molecular therapy oncolytics.

[214]  S. Bahrami,et al.  Fabrication and characterization of PCL/gelatin/curcumin nanofibers and their antibacterial properties , 2016 .

[215]  K. Nagahama,et al.  Discovery of a new function of curcumin which enhances its anticancer therapeutic potency , 2016, Scientific Reports.

[216]  Pedro Estrela,et al.  Introduction to biosensors , 2016, Essays in biochemistry.

[217]  Amjad Ali,et al.  Curcumin inhibits HIV-1 by promoting Tat protein degradation , 2016, Scientific Reports.

[218]  Yangchao Luo,et al.  Low density lipoprotein/pectin complex nanogels as potential oral delivery vehicles for curcumin , 2016 .

[219]  S. Dubas,et al.  Improved pH Sensing of Curcumin Loaded Polyelectrolyte Multilayers Thin Films , 2016 .

[220]  C. Selvam,et al.  Molecular mechanisms of curcumin and its semisynthetic analogues in prostate cancer prevention and treatment. , 2016, Life sciences.

[221]  Sharmistha Dey,et al.  Curcumin specifically binds to the human calcium–calmodulin-dependent protein kinase IV: fluorescence and molecular dynamics simulation studies , 2016, Journal of biomolecular structure & dynamics.

[222]  Liang Shen,et al.  How does curcumin work with poor bioavailability? Clues from experimental and theoretical studies , 2016, Scientific Reports.

[223]  Chen Li,et al.  Co-delivery of doxorubicin and curcumin by pH-sensitive prodrug nanoparticle for combination therapy of cancer , 2016, Scientific Reports.

[224]  S. Jalili,et al.  Study of curcumin behavior in two different lipid bilayer models of liposomal curcumin using molecular dynamics simulation , 2016, Journal of biomolecular structure & dynamics.

[225]  A. Kunnumakkara,et al.  Multi-Targeted Agents in Cancer Cell Chemosensitization: What We Learnt from Curcumin Thus Far. , 2016, Recent patents on anti-cancer drug discovery.

[226]  V. V. Padma,et al.  Wound dressings – a review , 2015, BioMedicine.

[227]  Hai Jin,et al.  Curcumin inhibits cell proliferation and induces apoptosis of human non-small cell lung cancer cells through the upregulation of miR-192-5p and suppression of PI3K/Akt signaling pathway. , 2015, Oncology reports.

[228]  P. Petit,et al.  Curcumin induces crosstalk between autophagy and apoptosis mediated by calcium release from the endoplasmic reticulum, lysosomal destabilization and mitochondrial events , 2015, Cell Death Discovery.

[229]  Anoop Kumar,et al.  Mechanism of immunoprotective effects of curcumin in DLM-induced thymic apoptosis and altered immune function: an in silico and in vitro study , 2015, Immunopharmacology and immunotoxicology.

[230]  T. Mohamed,et al.  Curcumin Binding to Beta Amyloid: A Computational Study , 2015, Chemical biology & drug design.

[231]  K. Hasegawa,et al.  Clinical applications of curcumin , 2015 .

[232]  P. Amin,et al.  Enhanced solubility and dissolution of curcumin by a hydrophilic polymer solid dispersion and its insilico molecular modeling studies , 2015 .

[233]  Kyung-Han Lee,et al.  Introduction of Methyl Groups at C2 and C6 Positions Enhances the Antiangiogenesis Activity of Curcumin , 2015, Scientific Reports.

[234]  A. Jerah,et al.  Curcumin binds in silico to anti-cancer drug target enzyme MMP-3 (human stromelysin-1) with affinity comparable to two known inhibitors of the enzyme , 2015, Bioinformation.

[235]  J. Snowden,et al.  The role of JAK/STAT signalling in the pathogenesis, prognosis and treatment of solid tumours , 2015, British Journal of Cancer.

[236]  Leonardo L. G. Ferreira,et al.  Molecular Docking and Structure-Based Drug Design Strategies , 2015, Molecules.

[237]  Gaozhi Chen,et al.  Insights into the binding mode of curcumin to MD-2: studies from molecular docking, molecular dynamics simulations and experimental assessments. , 2015, Molecular bioSystems.

[238]  H. Modarress,et al.  Molecular dynamics simulation study of chitosan and gemcitabine as a drug delivery system , 2015, Journal of Molecular Modeling.

[239]  M. Reddy,et al.  Molecular docking and simulation of Curcumin with Geranylgeranyl Transferase1 (GGTase1) and Farnesyl Transferase (FTase) , 2015, Bioinformation.

[240]  H. Zhang,et al.  Curcumin Promotes Cell Cycle Arrest and Inhibits Survival of Human Renal Cancer Cells by Negative Modulation of the PI3K/AKT Signaling Pathway , 2015, Cell Biochemistry and Biophysics.

[241]  Haixu Chen,et al.  Pretreatment of Adipose Derived Stem Cells with Curcumin Facilitates Myocardial Recovery via Antiapoptosis and Angiogenesis , 2015, Stem cells international.

[242]  Aniket Gade,et al.  Potential applications of curcumin and curcumin nanoparticles: from traditional therapeutics to modern nanomedicine , 2015 .

[243]  A. Budovsky,et al.  Effect of medicinal plants on wound healing , 2015, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[244]  H. Park,et al.  Modified curcumin with hyaluronic acid: Combination of pro-drug and nano-micelle strategy to address the curcumin challenge , 2015 .

[245]  Aamir Ahmad,et al.  Molecular docking and inhibition of matrix metalloproteinase-2 by novel difluorinatedbenzylidene curcumin analog. , 2015, American journal of translational research.

[246]  M. Coumar,et al.  Apoptosis induction by an analog of curcumin (BDMC-A) in human laryngeal carcinoma cells through intrinsic and extrinsic pathways , 2014, Cellular Oncology.

[247]  H. Bui,et al.  Fabrication and characterization of electrospun curcumin-loaded polycaprolactone-polyethylene glycol nanofibers for enhanced wound healing , 2014, Macromolecular Research.

[248]  Hui-jing Li,et al.  Synthesis and Biological Evaluation of Novel Curcuminoid Derivatives , 2014, Molecules.

[249]  J. Qin,et al.  Curcumin inhibits the invasion of thyroid cancer cells via down-regulation of PI3K/Akt signaling pathway. , 2014, Gene.

[250]  F. Gramatica,et al.  Antiproliferative effect of ASC-J9 delivered by PLGA nanoparticles against estrogen-dependent breast cancer cells. , 2014, Molecular pharmaceutics.

[251]  A. Alizadeh,et al.  Nanotechnology-Applied Curcumin for Different Diseases Therapy , 2014, BioMed research international.

[252]  Zhidong Lv,et al.  Curcumin induces apoptosis in breast cancer cells and inhibits tumor growth in vitro and in vivo. , 2014, International journal of clinical and experimental pathology.

[253]  K. Zandi,et al.  A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin , 2014, BioMed research international.

[254]  A. Sangamwar,et al.  Ensemble docking and molecular dynamics identify knoevenagel curcumin derivatives with potent anti-EGFR activity. , 2014, Gene.

[255]  D. Ormond,et al.  Stem Cell Therapy and Curcumin Synergistically Enhance Recovery from Spinal Cord Injury , 2014, PloS one.

[256]  S. Skariyachan,et al.  Exploring inhibitory potential of Curcumin against various cancer targets by in silico virtual screening , 2014, Interdisciplinary Sciences: Computational Life Sciences.

[257]  S. Yeh,et al.  Determination of androgen receptor degradation enhancer ASC-J9(®) in mouse sera and organs with liquid chromatography tandem mass spectrometry. , 2014, Journal of pharmaceutical and biomedical analysis.

[258]  M. Hosseinkhani,et al.  Tissue Engineered Scaffolds in Regenerative Medicine , 2014, World journal of plastic surgery.

[259]  Li-Fen Huang,et al.  Curcumin suppresses doxorubicin-induced epithelial-mesenchymal transition via the inhibition of TGF-β and PI3K/AKT signaling pathways in triple-negative breast cancer cells. , 2013, Journal of agricultural and food chemistry.

[260]  Patrick Couvreur,et al.  Stimuli-responsive nanocarriers for drug delivery. , 2013, Nature materials.

[261]  M. Raju,et al.  A comprehensive review on SAR of curcumin. , 2013, Mini reviews in medicinal chemistry.

[262]  P. Negi,et al.  Synthesis of amino acid conjugates of tetrahydrocurcumin and evaluation of their antibacterial and anti-mutagenic properties. , 2013, Food chemistry.

[263]  S. Yeh,et al.  Anti-androgen receptor ASC-J9 versus anti-androgens MDV3100 (Enzalutamide) or Casodex (Bicalutamide) leads to opposite effects on prostate cancer metastasis via differential modulation of macrophage infiltration and STAT3-CCL2 signaling , 2013, Cell Death and Disease.

[264]  F. Aqil,et al.  Bioavailability of phytochemicals and its enhancement by drug delivery systems. , 2013, Cancer letters.

[265]  Shirui Mao,et al.  Smart pH-sensitive and temporal-controlled polymeric micelles for effective combination therapy of doxorubicin and disulfiram. , 2013, ACS nano.

[266]  Arnab Ganguli,et al.  Apigenin shows synergistic anticancer activity with curcumin by binding at different sites of tubulin. , 2013, Biochimie.

[267]  H. Rupasinghe,et al.  Curcumin and Its Carbocyclic Analogs: Structure-Activity in Relation to Antioxidant and Selected Biological Properties , 2013, Molecules.

[268]  A. Chow,et al.  Highly Stabilized Curcumin Nanoparticles Tested in an In Vitro Blood–Brain Barrier Model and in Alzheimer’s Disease Tg2576 Mice , 2013, The AAPS Journal.

[269]  A. Noorafshan,et al.  A review of therapeutic effects of curcumin. , 2013, Current pharmaceutical design.

[270]  Xiao-guang Chen,et al.  Curcumin induces FasL-related apoptosis through p38 activation in human hepatocellular carcinoma Huh7 cells. , 2013, Life sciences.

[271]  Lin Mei,et al.  Paclitaxel drug delivery systems , 2013, Expert opinion on drug delivery.

[272]  Catherine A. Sugar,et al.  Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study , 2012, Alzheimer's Research & Therapy.

[273]  Anilesh Kumar,et al.  In silico inhibition studies of NF-κB p50 subunit by curcumin and its natural derivatives , 2012, Medicinal Chemistry Research.

[274]  Jun Li,et al.  Supramolecular anchoring of DNA polyplexes in cyclodextrin-based polypseudorotaxane hydrogels for sustained gene delivery. , 2012, Biomacromolecules.

[275]  Jong-Suk Kim,et al.  Curcumin suppresses the TPA-induced invasion through inhibition of PKCα-dependent MMP-expression in MCF-7 human breast cancer cells. , 2012, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[276]  Zheng Wang,et al.  Biodegradable Polymer-Curcumin Conjugate Micelles Enhance the Loading and Delivery of Low-Potency Curcumin , 2012, Pharmaceutical Research.

[277]  Guanhong Xu,et al.  The Three Dimensional Quantitative Structure Activity Relationships (3D-QSAR) and Docking Studies of Curcumin Derivatives as Androgen Receptor Antagonists , 2012, International journal of molecular sciences.

[278]  M. Murali,et al.  In Silico, In Vitro and In Vivo Assessment of Safety and Anti-inflammatory Activity of Curcumin , 2012 .

[279]  Umashankar Vetrivel,et al.  In vitro and In silico studies on inhibitory effects of curcumin on multi drug resistance associated protein (MRP1) in retinoblastoma cells , 2012, Bioinformation.

[280]  Yuanyuan Shen,et al.  Polymeric micelles for parenteral delivery of curcumin: Preparation, characterization and in vitro evaluation , 2011 .

[281]  Raju C Reddy,et al.  Curcumin-Loaded Apotransferrin Nanoparticles Provide Efficient Cellular Uptake and Effectively Inhibit HIV-1 Replication In Vitro , 2011, PloS one.

[282]  K. Chennazhi,et al.  Curcumin loaded fibrinogen nanoparticles for cancer drug delivery. , 2011, Journal of biomedical nanotechnology.

[283]  K. Chennazhi,et al.  Curcumin-loaded biocompatible thermoresponsive polymeric nanoparticles for cancer drug delivery. , 2011, Journal of colloid and interface science.

[284]  B. Aggarwal,et al.  A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer , 2011, Cancer Chemotherapy and Pharmacology.

[285]  M. Mezei,et al.  Molecular docking: a powerful approach for structure-based drug discovery. , 2011, Current computer-aided drug design.

[286]  E. Srivatsan,et al.  Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma , 2011, Molecular Cancer.

[287]  C. Sudarsanakumar,et al.  Molecular dynamics simulations and binding free energy analysis of DNA minor groove complexes of curcumin , 2011, Journal of molecular modeling.

[288]  Jun Du,et al.  Synthesis and identification of new 4-arylidene curcumin analogues as potential anticancer agents targeting nuclear factor-κB signaling pathway. , 2010, Journal of medicinal chemistry.

[289]  G. Bar-Sela,et al.  Curcumin and Gemcitabine in Patients With Advanced Pancreatic Cancer , 2010, Nutrition and Cancer.

[290]  Murali M. Yallapu,et al.  Fabrication of curcumin encapsulated PLGA nanoparticles for improved therapeutic effects in metastatic cancer cells. , 2010, Journal of colloid and interface science.

[291]  P. Neri,et al.  Management of chronic anterior uveitis relapses: efficacy of oral phospholipidic curcumin treatment. Long-term follow-up , 2010, Clinical ophthalmology.

[292]  M. Diederich,et al.  Synthesis and cytotoxic potential of heterocyclic cyclohexanone analogues of curcumin. , 2010, Bioorganic & medicinal chemistry.

[293]  Yong-Jun Jiang,et al.  Molecular docking and molecular dynamics simulation studies of GPR40 receptor-agonist interactions. , 2010, Journal of molecular graphics & modelling.

[294]  N. K. Jain,et al.  Non-polymeric nano-carriers in HIV/AIDS drug delivery and targeting. , 2010, Advanced drug delivery reviews.

[295]  Hai-Bin Luo,et al.  Binding of curcumin with glyoxalase I: Molecular docking, molecular dynamics simulations, and kinetics analysis. , 2010, Biophysical chemistry.

[296]  B. Aggarwal,et al.  Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer through the downregulation of NF-kappaB and upregulation of TRAIL receptors. , 2009, Cancer research.

[297]  C. Van Waes,et al.  Nuclear NF-κB p65 Phosphorylation at Serine 276 by Protein Kinase A Contributes to the Malignant Phenotype of Head and Neck Cancer , 2009, Clinical Cancer Research.

[298]  K. Lee,et al.  Novel anti-prostate cancer curcumin analogues that enhance androgen receptor degradation activity. , 2009, Anti-cancer agents in medicinal chemistry.

[299]  Makoto Takahashi,et al.  Evaluation of an oral carrier system in rats: bioavailability and antioxidant properties of liposome-encapsulated curcumin. , 2009, Journal of agricultural and food chemistry.

[300]  O. Werz,et al.  Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1 , 2009, Molecular Cancer Therapeutics.

[301]  A. Kabanov,et al.  Nanogels as pharmaceutical carriers: finite networks of infinite capabilities. , 2009, Angewandte Chemie.

[302]  K. S. Parvathy,et al.  Antioxidant, antimutagenic and antibacterial activities of curcumin-β-diglucoside , 2009 .

[303]  Julie S. Jurenka.  Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. , 2009, Alternative medicine review : a journal of clinical therapeutic.

[304]  M. Saladini,et al.  Synthesis, cytotoxic and combined cDDP activity of new stable curcumin derivatives. , 2009, Bioorganic & medicinal chemistry.

[305]  S. Suresh,et al.  Novel formulation of solid lipid microparticles of curcumin for anti‐angiogenic and anti‐inflammatory activity for optimization of therapy of inflammatory bowel disease , 2009 .

[306]  T. Burke,et al.  An in vitro study of liposomal curcumin: stability, toxicity and biological activity in human lymphocytes and Epstein-Barr virus-transformed human B-cells. , 2009, International journal of pharmaceutics.

[307]  B. Aggarwal,et al.  Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature. , 2008, Biochemical pharmacology.

[308]  E. Srivatsan,et al.  Liposome-Encapsulated Curcumin Suppresses Growth of Head and Neck Squamous Cell Carcinoma In vitro and in Xenografts through the Inhibition of Nuclear Factor κB by an AKT-Independent Pathway , 2008, Clinical Cancer Research.

[309]  Sarah N. Hilmer,et al.  ADME-tox issues for the elderly , 2008 .

[310]  S. Kulkarni,et al.  Antidepressant activity of curcumin: involvement of serotonin and dopamine system , 2008, Psychopharmacology.

[311]  R. Lai,et al.  Micelles of poly(ethylene oxide)-b-poly(epsilon-caprolactone) as vehicles for the solubilization, stabilization, and controlled delivery of curcumin. , 2008, Journal of biomedical materials research. Part A.

[312]  Razelle Kurzrock,et al.  Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer , 2008, Clinical Cancer Research.

[313]  M. Bharath,et al.  Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo: therapeutic implications for Parkinson's disease explained via in silico studies. , 2008, Free radical biology & medicine.

[314]  E. De Clercq,et al.  Design, synthesis, and cytostatic activity of novel cyclic curcumin analogues. , 2007, Bioorganic & medicinal chemistry letters.

[315]  P. Pristovsek,et al.  MD‐2 as the target of curcumin in the inhibition of response to LPS , 2007, Journal of leukocyte biology.

[316]  B. Aggarwal,et al.  Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. , 2007, Carcinogenesis.

[317]  M. Saladini,et al.  Synthesis and characterization of new β-diketo derivatives with iron chelating ability , 2007 .

[318]  E. Antunes,et al.  Curcuminoids, curcumin, and demethoxycurcumin reduce lead-induced memory deficits in male Wistar rats. , 2007, Journal of agricultural and food chemistry.

[319]  Michael T Longaker,et al.  Progress and potential for regenerative medicine. , 2007, Annual review of medicine.

[320]  M. Sata,et al.  Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial. , 2006, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[321]  B. Aggarwal,et al.  Novel curcumin analogs targeting TNF-induced NF-kappaB activation and proliferation in human leukemic KBM-5 cells. , 2006, Bioorganic & medicinal chemistry.

[322]  T. Gilmore.  Introduction to NF-κB: players, pathways, perspectives , 2006, Oncogene.

[323]  E. Bobrovnikova-Marjon,et al.  Activation of NFκB is inhibited by curcumin and related enones , 2006 .

[324]  Afsaneh Lavasanifar,et al.  Polymeric micelles for drug delivery , 2006, Expert opinion on drug delivery.

[325]  Jong-Wook Park,et al.  Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5). , 2005, Carcinogenesis.

[326]  J. McNeill,et al.  Synthesis and characterization of dual function vanadyl, gallium and indium curcumin complexes for medicinal applications. , 2005, Journal of inorganic biochemistry.

[327]  S. Katz,et al.  Curcumin Therapy in Inflammatory Bowel Disease: A Pilot Study , 2005, Digestive Diseases and Sciences.

[328]  S. Padhye,et al.  Antioxidant and antiproliferative activity of curcumin semicarbazone. , 2005, Bioorganic & medicinal chemistry letters.

[329]  A. Lavasanifar,et al.  Micelles of methoxy poly(ethylene oxide)-b-poly(epsilon-caprolactone) as vehicles for the solubilization and controlled delivery of cyclosporine A. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[330]  C. Yeh,et al.  Inhibition of NFκB Activation with Curcumin Attenuates Plasma Inflammatory Cytokines Surge and Cardiomyocytic Apoptosis Following Cardiac Ischemia/Reperfusion1 , 2005 .

[331]  S. Jachak,et al.  Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents. , 2005, Bioorganic & medicinal chemistry letters.

[332]  Roli Mishra,et al.  Design, development and synthesis of mixed bioconjugates of piperic acid-glycine, curcumin-glycine/alanine and curcumin-glycine-piperic acid and their antibacterial and antifungal properties. , 2005, Bioorganic & medicinal chemistry.

[333]  Fusheng Yang,et al.  Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo* , 2005, Journal of Biological Chemistry.

[334]  Donald J L Jones,et al.  Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences. , 2005, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[335]  J. McNeill,et al.  Complementary inhibition of synoviocyte, smooth muscle cell or mouse lymphoma cell proliferation by a vanadyl curcumin complex compared to curcumin alone. , 2004, Journal of inorganic biochemistry.

[336]  So-Jung Park,et al.  A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function. , 2004, Chemistry & biology.

[337]  Sujay K. Singh,et al.  Inhibition of growth and survival of human head and neck squamous cell carcinoma cells by curcumin via modulation of nuclear factor‐κB signaling , 2004 .

[338]  Tirunelveli S. Ramalingam,et al.  Curcumin Suppresses Growth of Head and Neck Squamous Cell Carcinoma , 2004, Clinical Cancer Research.

[339]  M. Ramírez-Silva,et al.  Determination of acidity constants of curcumin in aqueous solution and apparent rate constant of its decomposition. , 2004, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

[340]  P. Cullis,et al.  Drug Delivery Systems: Entering the Mainstream , 2004, Science.

[341]  Yi Li,et al.  In silico ADME/Tox: why models fail , 2003, J. Comput. Aided Mol. Des..

[342]  B. Aggarwal,et al.  Cigarette smoke condensate activates nuclear transcription factor-κB through phosphorylation and degradation of IκBα: correlation with induction of cyclooxygenase-2 , 2002 .

[343]  Dong Hoon Kim,et al.  Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation. , 2002, Bioorganic & medicinal chemistry.

[344]  M. Karin,et al.  Missing Pieces in the NF-κB Puzzle , 2002, Cell.

[345]  D. Newman,et al.  Natural Product Drug Discovery in the Next Millennium , 2001, Pharmaceutical biology.

[346]  R. C. Srimal,et al.  Role of curcumin in idiopathic inflammatory orbital pseudotumours , 2000, Phytotherapy research : PTR.

[347]  Toshiyuki Yamamoto,et al.  Monocyte Chemoattractant Protein-1 Enhances Gene Expression and Synthesis of Matrix Metalloproteinase-1 in Human Fibroblasts by an Autocrine IL-1α Loop1 , 2000, The Journal of Immunology.

[348]  S. Khopde,et al.  Inhibition of Radiation-Induced Lipid Peroxidation by Tetrahydrocurcumin: Possible Mechanisms by Pulse Radiolysis , 2000, Bioscience, biotechnology, and biochemistry.

[349]  L. Howells,et al.  Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-κB activation via the NIK/IKK signalling complex , 1999, Oncogene.

[350]  R. Prasad,et al.  Efficacy of Curcumin in the Management of Chronic Anterior Uveitis , 1999, Phytotherapy research : PTR.

[351]  N. Altorki,et al.  Curcumin inhibits cyclooxygenase-2 transcription in bile acid- and phorbol ester-treated human gastrointestinal epithelial cells. , 1999, Carcinogenesis.

[352]  L. O’Neill,et al.  Inhibition of nuclear factor kappaB by direct modification in whole cells--mechanism of action of nordihydroguaiaritic acid, curcumin and thiol modifiers. , 1998, Biochemical pharmacology.

[353]  M. Karin,et al.  Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. , 1997, The New England journal of medicine.

[354]  T. Osawa,et al.  Involvement of the beta-diketone moiety in the antioxidative mechanism of tetrahydrocurcumin. , 1996, Biochemical pharmacology.

[355]  B. Aggarwal,et al.  The p60 Tumor Necrosis Factor (TNF) Receptor-associated Kinase (TRAK) Binds Residues 344–397 within the Cytoplasmic Domain Involved in TNF Signaling (*) , 1995, The Journal of Biological Chemistry.

[356]  M. Chan.  Inhibition of tumor necrosis factor by curcumin, a phytochemical. , 1995, Biochemical pharmacology.

[357]  C. H. Price,et al.  The role of receptor binding in drug discovery. , 1993, Journal of natural products.

[358]  A. Conney,et al.  Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. , 1991, Cancer research.

[359]  F. Stern,et al.  Patterns of psychological decompensation in patients with spinal cord syndromes. , 1969, Diseases of the nervous system.

[360]  Y. Tan,et al.  Evaluation of Anti-Cancer and Anti-Metastatic Effects of Folate-PEGylated Niosome for Co-Delivery of Letrozole and Ascorbic Acid on Breast Cancer Cells , 2022, Molecular Systems Design & Engineering.

[361]  N. Huda,et al.  Development of curcumin/rice starch films for sensitive detection of hypoxanthine in chicken and fish meat , 2022, Carbohydrate Polymer Technologies and Applications.

[362]  Zhiqiang Yu,et al.  Stimuli-responsive nanotherapeutics for precision drug delivery and cancer therapy. , 2019, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

[363]  M. Rabiee,et al.  Curcumin-hybrid Nanoparticles in Drug Delivery System , 2018 .

[364]  J. Rajendhran,et al.  Enhancing the anti-gastric cancer activity of curcumin with biocompatible and pH sensitive PMMA-AA/ZnO nanoparticles. , 2018, Materials science & engineering. C, Materials for biological applications.

[365]  Cristian C. Villa,et al.  Development of native and modified banana starch nanoparticles as vehicles for curcumin. , 2018, International journal of biological macromolecules.

[366]  Duxin Sun,et al.  Bringing Curcumin to the Clinic in Cancer Prevention: a Review of Strategies to Enhance Bioavailability and Efficacy , 2016, The AAPS Journal.

[367]  I. Tvaroška,et al.  Molecular dynamic studies of amyloid-beta interactions with curcumin and Cu2+ ions , 2015, Chemical Papers.

[368]  L. Helson.  Curcumin (diferuloylmethane) delivery methods: A review , 2013, BioFactors.

[369]  K. Priyadarsini.  Chemical and structural features influencing the biological activity of curcumin. , 2013, Current pharmaceutical design.

[370]  S. Nakornchai,et al.  Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives. , 2007, Biological & pharmaceutical bulletin.

[371]  N. Perkins,et al.  Integrating cell-signalling pathways with NF-κB and IKK function , 2007, Nature Reviews Molecular Cell Biology.

[372]  A. Brasier.  The NF-κB regulatory network , 2007, Cardiovascular Toxicology.

[373]  T. Horie,et al.  Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages. , 1999, Pharmacological research.