Influence of pH on osteoclasts treated with zoledronate and alendronate

[1]  O. García-Martínez,et al.  Bisphosphonate Modulation of the Gene Expression of Different Markers Involved in Osteoblast Physiology: Possible Implications in Bisphosphonate-Related Osteonecrosis of the Jaw , 2018, International journal of medical sciences.

[2]  F. Manzi,et al.  Effect of 1% sodium alendronate in the non-surgical treatment of periodontal intraosseous defects: a 6-month clinical trial , 2017, Journal of applied oral science : revista FOB.

[3]  A. Pradeep,et al.  Role of 1% alendronate gel as adjunct to mechanical therapy in the treatment of chronic periodontitis among smokers , 2017, Journal of applied oral science : revista FOB.

[4]  O. García-Martínez,et al.  Nitrogen-containing bisphosphonates modulate the antigenic profile and inhibit the maturation and biomineralization potential of osteoblast-like cells , 2015, Clinical Oral Investigations.

[5]  O. García-Martínez,et al.  High doses of bisphosphonates reduce osteoblast-like cell proliferation by arresting the cell cycle and inducing apoptosis. , 2015, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[6]  O. García-Martínez,et al.  Effects on Growth of Human Osteoblast-Like Cells of Three Nonsteroidal Anti-Inflammatory Drugs , 2015, Biological research for nursing.

[7]  Yong-Dae Kwon,et al.  Bisphosphonates modulate the expression of OPG and M-CSF in hMSC-derived osteoblasts , 2012, Clinical Oral Investigations.

[8]  G. Mast,et al.  Bisphosphonate-related osteonecrosis of the jaws - characteristics, risk factors, clinical features, localization and impact on oncological treatment. , 2012, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[9]  M. Schieker,et al.  Osteonecrosis of the jaw: effect of bisphosphonate type, local concentration, and acidic milieu on the pathomechanism. , 2010, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[10]  T. Arnett Acidosis, hypoxia and bone. , 2010, Archives of biochemistry and biophysics.

[11]  M. Schieker,et al.  Bisphosphonate-related osteonecrosis of the jaw: is pH the missing part in the pathogenesis puzzle? , 2010, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[12]  L. Assael,et al.  American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws--2009 update. , 2009, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[13]  S. Cremers,et al.  Inhibition of oral mucosal cell wound healing by bisphosphonates. , 2008, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[14]  T. Arnett Extracellular pH regulates bone cell function. , 2008, The Journal of nutrition.

[15]  N. Watts,et al.  Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy , 2008, Osteoporosis International.

[16]  R. Marx,et al.  Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment. , 2007, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[17]  I. McQuaker,et al.  Oral sodium clodronate induced osteonecrosis of the jaw in a patient with myeloma , 2007, European journal of haematology.

[18]  G. H. Nancollas,et al.  Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite. , 2006, Bone.

[19]  R. Marx Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. , 2003, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[20]  T. J. Rosenberg,et al.  Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases. , 2004, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[21]  T. Arnett,et al.  Hypoxia is a major stimulator of osteoclast formation and bone resorption , 2003, Journal of cellular physiology.

[22]  P. LoRusso,et al.  Pharmacokinetics and Pharmacodynamics of Zoledronic Acid in Cancer Patients with Bone Metastases , 2002, Journal of clinical pharmacology.

[23]  J. Mönkkönen,et al.  The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis. , 2001, Arthritis and rheumatism.

[24]  J. Mönkkönen,et al.  Cellular and molecular mechanisms of action of bisphosphonates , 2000, Cancer.

[25]  A. Harris,et al.  Macrophage responses to hypoxia: relevance to disease mechanisms , 1999, Journal of leukocyte biology.

[26]  G. Burnstock,et al.  ATP is a potent stimulator of the activation and formation of rodent osteoclasts , 1998, The Journal of physiology.

[27]  G. Rodan,et al.  Bisphosphonates: mechanisms of action , 1998, Endocrine reviews.

[28]  T. Arnett,et al.  Modulation of the resorptive activity of rat osteoclasts by small changes in extracellular pH near the physiological range. , 1996, Bone.

[29]  G. Rodan,et al.  Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure. , 1991, The Journal of clinical investigation.

[30]  C. Langefeld,et al.  Enhanced stimulation of human bone marrow macrophage colony formation in vitro by recombinant human macrophage colony-stimulating factor in agarose medium and at low oxygen tension. , 1990, Blood.

[31]  D. Dempster,et al.  A comparative study of disaggregated chick and rat osteoclasts in vitro: effects of calcitonin and prostaglandins. , 1987, Endocrinology.

[32]  D. Dempster,et al.  Effect of pH on bone resorption by rat osteoclasts in vitro. , 1986, Endocrinology.

[33]  G. Mandell,et al.  pO2, pH, and Redox Potential of Experimental Abscesses , 1974, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[34]  R. Marx A decade of bisphosphonate bone complications: what it has taught us about bone physiology. , 2014, The International journal of oral & maxillofacial implants.

[35]  T. Arnett,et al.  Rodent osteoclast cultures. , 2012, Methods in molecular biology.

[36]  D. Burr,et al.  THe effects of suppressed bone remodeling by bisphosphonates on microdamage accumulation and degree of mineralization in the cortical bone of dog rib , 2009, Journal of Bone and Mineral Metabolism.

[37]  B. Klosterhalfen,et al.  [Artificial pressure increase in subcutaneous abscess with evidence of general systemic reaction]. , 1997, Archiv fuer Klinische Chirurgie.

[38]  E. Papoutsakis,et al.  Reduced oxygen tension increases hematopoiesis in long-term culture of human stem and progenitor cells from cord blood and bone marrow. , 1992, Experimental hematology.