Increased Accumulation of Intraneuronal Amyloid β in HIV-Infected Patients
暂无分享,去创建一个
E. Masliah | C. Achim | I. Everall | A. Adame | Wilmar Dumaop | Hnrc
[1] F. Gage,et al. Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice , 2008, BMC Neuroscience.
[2] E. Koo,et al. Amyloid Precursor Protein Trafficking, Processing, and Function* , 2008, Journal of Biological Chemistry.
[3] C. Glabe,et al. Structural Classification of Toxic Amyloid Oligomers* , 2008, Journal of Biological Chemistry.
[4] R. Kayed,et al. Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin , 2008, Molecular Neurodegeneration.
[5] E. Masliah,et al. Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases , 2008, PloS one.
[6] D. Selkoe,et al. Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior , 2008, Behavioural Brain Research.
[7] T. Wisniewski,et al. Amyloid-β immunisation for Alzheimer's disease , 2008, The Lancet Neurology.
[8] Brian Spencer,et al. The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. , 2008, The Journal of clinical investigation.
[9] E. Masliah,et al. Activation of the Amyloid Cascade in Apolipoprotein E4 Transgenic Mice Induces Lysosomal Activation and Neurodegeneration Resulting in Marked Cognitive Deficits , 2008, The Journal of Neuroscience.
[10] G. Rebeck,et al. Regulated Proteolysis of APP and ApoE Receptors , 2008, Molecular Neurobiology.
[11] S. Love,et al. Abeta-degrading enzymes in Alzheimer's disease. , 2008, Brain pathology.
[12] M. Wolfe. Gamma-secretase inhibition and modulation for Alzheimer's disease. , 2008, Current Alzheimer research.
[13] R. Postina. A closer look at alpha-secretase. , 2008, Current Alzheimer research.
[14] N. Belyaev,et al. Amyloid-degrading enzymes as therapeutic targets in Alzheimer's disease. , 2008, Current Alzheimer research.
[15] A. Cuello,et al. Impact of Intracellular β-Amyloid in Transgenic Animals and Cell Models , 2008, Neurodegenerative Diseases.
[16] D. Sulzer,et al. Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis , 2008, PLoS pathogens.
[17] B. Ances,et al. Role of psychiatric medications as adjunct therapy in the treatment of HIV associated neurocognitive disorders , 2008, International review of psychiatry.
[18] E. Masliah,et al. Neurobiology of HIV , 2008, International review of psychiatry.
[19] V. Mollace,et al. N-acetylcysteine prevents HIV gp 120-related damage of human cultured astrocytes: correlation with glutamine synthase dysfunction , 2007, BMC Neuroscience.
[20] M. Alizon,et al. Identification of a Postendocytic Sorting Sequence in CCR5 , 2007, Molecular Pharmacology.
[21] Ralph A. Nixon,et al. Autophagy, amyloidogenesis and Alzheimer disease , 2007, Journal of Cell Science.
[22] M. Findeis. The role of amyloid β peptide 42 in Alzheimer's disease , 2007 .
[23] M. Szyf,et al. High intracellular concentrations of amyloid‐beta block nuclear translocation of phosphorylated CREB , 2007, Journal of neurochemistry.
[24] Long-chuan Yu,et al. The role of intracellular amyloid β in Alzheimer's disease , 2007, Progress in Neurobiology.
[25] Maria Flora Salvatori,et al. Persistence of Neuropsychologic Deficits Despite Long-TermHighlyActiveAntiretroviralTherapyinPatients With HIV-Related Neurocognitive Impairment: Prevalence and Risk Factors , 2007, Journal of acquired immune deficiency syndromes.
[26] Marinos C. Dalakas,et al. β‐Amyloid is a substrate of autophagy in sporadic inclusion body myositis , 2007 .
[27] D. Selkoe,et al. The APP family of proteins: similarities and differences. , 2007, Biochemical Society transactions.
[28] E. V. Bockstaele,et al. Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis , 2006, Gene Therapy.
[29] J. Corbeil,et al. Diminished somatostatin gene expression in individuals with HIV and major depressive disorder , 2006, Neurology.
[30] W. Banks,et al. A novel antioxidant N-acetylcysteine amide prevents gp120- and Tat-induced oxidative stress in brain endothelial cells , 2006, Experimental Neurology.
[31] K. Jellinger. Challenges in neuronal apoptosis. , 2006, Current Alzheimer research.
[32] B. Levine,et al. HIV and CXCR4 in a kiss of autophagic death. , 2006, The Journal of clinical investigation.
[33] P. Gorry,et al. Mechanisms of HIV-1 neurotropism. , 2006, Current HIV research.
[34] M. Wolfe. The γ-Secretase Complex: Membrane-Embedded Proteolytic Ensemble , 2006 .
[35] J. Busciglio,et al. Different Conformations of Amyloid β Induce Neurotoxicity by Distinct Mechanisms in Human Cortical Neurons , 2006, The Journal of Neuroscience.
[36] J. Marcusson,et al. Oxidative Stress Induces Intralysosomal Accumulation of Alzheimer Amyloid β‐Protein in Cultured Neuroblastoma Cells , 2006, Annals of the New York Academy of Sciences.
[37] D. Dickson,et al. β-Amyloid Degradation and Alzheimer's Disease , 2006, Journal of biomedicine & biotechnology.
[38] J. Standridge. Vicious cycles within the neuropathophysiologic mechanisms of Alzheimer's disease. , 2006, Current Alzheimer research.
[39] Gopal Thinakaran,et al. Amyloidogenic processing of β-amyloid precursor protein in intracellular compartments , 2006, Neurology.
[40] Y. Lyubchenko,et al. Physicochemical characteristics of soluble oligomeric Aβ and their pathologic role in Alzheimer's disease , 2005, Neurological research.
[41] N. Kumaragurubaran,et al. Recent Developments of Structure Based β-Secretase Inhibitors for Alzheimers Disease , 2005 .
[42] P. Keller,et al. Globular amyloid β‐peptide1−42 oligomer − a homogenous and stable neuropathological protein in Alzheimer's disease , 2005 .
[43] C. Eckman,et al. Aβ-degrading enzymes: modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention , 2005 .
[44] L. Tjernberg,et al. Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease , 2005, The Journal of cell biology.
[45] E. Masliah,et al. Lysosomal pathology associated with α‐synuclein accumulation in transgenic models using an eGFP fusion protein , 2005, Journal of neuroscience research.
[46] Jill A. White,et al. Differential effects of oligomeric and fibrillar amyloid-β1–42 on astrocyte-mediated inflammation , 2005, Neurobiology of Disease.
[47] G. Schettini,et al. The amyloid precursor protein and its network of interacting proteins: physiological and pathological implications , 2005, Brain Research Reviews.
[48] E. Masliah,et al. Brain deposition of beta-amyloid is a common pathologic feature in HIV positive patients , 2005, AIDS.
[49] Lynn Pulliam,et al. HIV-1 Tat inhibits neprilysin and elevates amyloid β , 2005 .
[50] L. Hersh,et al. Tat and amyloid: multiple interactions. , 2005, AIDS.
[51] O. Selnes,et al. Diabetes, Insulin Resistance, and Dementia Among HIV-1-Infected Patients , 2005, Journal of acquired immune deficiency syndromes.
[52] A. Cuello. Intracellular and Extracellular Aβ, a Tale of Two Neuropathologies , 2005, Brain pathology.
[53] Y. Liu,et al. Age, apolipoprotein E4, and the risk of HIV dementia: the Hawaii Aging with HIV Cohort , 2004, Journal of Neuroimmunology.
[54] B. Lamb,et al. Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease. , 2004, The international journal of biochemistry & cell biology.
[55] E. Masliah,et al. Altered P‐Glycoprotein Expression in AIDS Patients with HIV Encephalitis , 2004, Journal of neuropathology and experimental neurology.
[56] O. Selnes,et al. Higher frequency of dementia in older HIV-1 individuals , 2004, Neurology.
[57] L. Pulliam,et al. P3-371 HIV-1 TAT inhibits neprilysin and elevates amyloid beta , 2004, Neurobiology of Aging.
[58] V. Valcour,et al. HIV-associated dementia, mitochondrial dysfunction, and oxidative stress. , 2004, Mitochondrion.
[59] Christina A. Wilson,et al. Degradative organelles containing mislocalized α- and β-synuclein proliferate in presenilin-1 null neurons , 2004, The Journal of cell biology.
[60] J. Becker,et al. Prevalence of cognitive disorders differs as a function of age in HIV virus infection , 2004, AIDS.
[61] A. Takashima,et al. Specific Compositions of Amyloid-β Peptides as the Determinant of Toxic β-Aggregation* , 2003, Journal of Biological Chemistry.
[62] J. Garcia,et al. Inhibition of Endosomal/Lysosomal Degradation Increases the Infectivity of Human Immunodeficiency Virus , 2002, Journal of Virology.
[63] A. Cuello,et al. Intracellular A-beta amyloid, A sign for worse things to come? , 2002, Molecular Neurobiology.
[64] V. Perry,et al. Accumulation of β‐Amyloid Precursor Protein in Axons Correlates with CNS Expression of SIV gp41 , 2002 .
[65] M. Mallory,et al. Early formation of mature amyloid‐β protein deposits in a mutant APP transgenic model depends on levels of Aβ1–42 , 2001, Journal of neuroscience research.
[66] M. Grassi,et al. Beta amyloid precursor protein and patterns of HIV p24 immunohistochemistry in different brain areas of AIDS patients , 2001, AIDS.
[67] P. Stopka,et al. Quinolinic acid — Iron(II) complexes: Slow autoxidation, but enhanced hydroxyl radical production in the Fenton reaction , 2001, Free radical research.
[68] D. Cooper,et al. Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: acohort study , 1999, The Lancet.
[69] Chrétien,et al. Neuronal apoptosis does not correlate with dementia in HIV infection but is related to microglial activation and axonal damage , 1999, Neuropathology and applied neurobiology.
[70] M. Esiri,et al. Prevalence of Alzheimer plaques in AIDS , 1998, Journal of neurology, neurosurgery, and psychiatry.
[71] F. Scaravilli,et al. Axonal Damage Revealed by Accumulation of β‐APP in HIV‐positive Individuals without AIDS , 1997, Journal of neuropathology and experimental neurology.
[72] F. Scaravilli,et al. Accumulation of β‐amyloid precursor protein in HIV encephalitis: Relationship with neuropsychological abnormalities , 1997 .
[73] M. Esiri,et al. Cerebral white matter damage in HIV infection demonstrated using β-amyloid precursor protein immunoreactivity , 1997, Acta Neuropathologica.
[74] R. Mrak,et al. Glial Cytokines as Neuropathogenic Factors in HIV Infection: Pathogenic Similarities to Alzheimer's Disease , 1994, Journal of neuropathology and experimental neurology.
[75] C. Achim,et al. Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brains. , 1993, The Journal of clinical investigation.
[76] D. Dickson,et al. Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease , 1993, Glia.
[77] E. Masliah,et al. Spectrum of human immunodeficiency virus–associated neocortical damage , 1992, Annals of neurology.
[78] L. Hersh,et al. Tat peptides inhibit neprilysin , 2011, Journal of NeuroVirology.
[79] K. Roth,et al. The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy. , 2008, Frontiers in bioscience : a journal and virtual library.
[80] M. Wolfe. Gamma-secretase: structure, function, and modulation for Alzheimer's disease. , 2008, Current topics in medicinal chemistry.
[81] J. Lünemann,et al. Beta-amyloid is a substrate of autophagy in sporadic inclusion body myositis. , 2007, Annals of neurology.
[82] Howard E Gendelman,et al. Oxidative stress and the pathogenesis of neurodegenerative disorders. , 2007, International review of neurobiology.
[83] Long-chuan Yu,et al. The role of intracellular amyloid beta in Alzheimer's disease. , 2007, Progress in neurobiology.
[84] M. Findeis. The role of amyloid beta peptide 42 in Alzheimer's disease. , 2007, Pharmacology & therapeutics.
[85] M. Wolfe. The gamma-secretase complex: membrane-embedded proteolytic ensemble. , 2006, Biochemistry.
[86] D. Rubinsztein,et al. Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications. , 2006, Current topics in developmental biology.
[87] P. Keller,et al. Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease. , 2005, Journal of neurochemistry.
[88] C. Eckman,et al. Abeta-degrading enzymes: modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention. , 2005, Biochemical Society transactions.
[89] N. Kumaragurubaran,et al. Recent developments of structure based beta-secretase inhibitors for Alzheimer's disease. , 2005, Current topics in medicinal chemistry.
[90] V. Valcour,et al. Cognitive impairment in older HIV-1-seropositive individuals: prevalence and potential mechanisms. , 2004, AIDS.
[91] A. Takashima,et al. Specific compositions of amyloid-beta peptides as the determinant of toxic beta-aggregation. , 2003, The Journal of biological chemistry.
[92] K. Jellinger,et al. Problems of cell death in neurodegeneration and Alzheimer's Disease. , 2001, Journal of Alzheimer's disease : JAD.
[93] E. Iżycka-Świeszewska,et al. Vasculopathy and amyloid beta reactivity in brains of patients with acquired immune deficiency (AIDS). , 2000, Folia neuropathologica.
[94] M. Szyf,et al. Aß Immunoreactive Material Is Present in Several Intracellular Compartments in Transfected, Neuronally Differentiated, P19 Cells Expressing the Human Amyloid ß-Protein Precursor , 2000 .
[95] M. Szyf,et al. Abeta immunoreactive material is present in several intracellular compartments in transfected, neuronally differentiated, P19 cells expressing the human amyloid beta-protein precursor. , 2000, Journal of Alzheimer's disease : JAD.
[96] A. Roses,et al. CELLULAR LOCALIZATION OF MESSENGER RNA ENCODING AMYLOID‐BETA-PROTEIN IN NORMAL TISSUE AND IN ALZHEIMER DISEASE , 1988, Alzheimer disease and associated disorders.