Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain.

[1]  R. Löbenberg,et al.  Body distribution of azidothymidine bound to hexyl-cyanoacrylate nanoparticles after i.v. injection to rats. , 1998, Journal of controlled release : official journal of the Controlled Release Society.

[2]  A. Kuin,et al.  Cellular pharmacokinetics and cytotoxicity of camptothecin and topotecan at normal and acidic pH. , 1997, Cancer research.

[3]  H. Bunjes,et al.  Physicochemical characterization of lipid nanoparticles and evaluation of their drug loading capacity and sustained release potential , 1997 .

[4]  R. Müller,et al.  Solid lipid nanoparticles (SLN) as potential carrier for human use: interaction with human granulocytes , 1997 .

[5]  Y. Sai,et al.  Blood‐brain‐barrier Transport of Lipid Microspheres Containing Clinprost, a Prostaglandin I2 Analogue , 1996, The Journal of pharmacy and pharmacology.

[6]  S. Moghimi Mechanisms regulating body distribution of nanospheres conditioned with pluronic and tetronic block co-polymers , 1995 .

[7]  J. Kreuter,et al.  Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles) , 1995, Brain Research.

[8]  T. Burke,et al.  Differential interactions of camptothecin lactone and carboxylate forms with human blood components. , 1994, Biochemistry.

[9]  R. Müller,et al.  Solid lipid nanoparticles (SLN) for controlled drug delivery. I. Production, characterization and sterilization , 1994 .

[10]  M. Potměšil,et al.  Camptothecins: from bench research to hospital wards. , 1994, Cancer research.

[11]  T. Burke,et al.  The structural basis of camptothecin interactions with human serum albumin: impact on drug stability. , 1994, Journal of medicinal chemistry.

[12]  H. Rosing,et al.  High-performance liquid chromatographic analysis of the antitumour drug camptothecin and its lactone ring-opened form in rat plasma. , 1993, Journal of chromatography.

[13]  B. Giovanella,et al.  Complete growth inhibition of human cancer xenografts in nude mice by treatment with 20-(S)-camptothecin. , 1991, Cancer research.

[14]  L. Liu,et al.  DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts. , 1989, Science.

[15]  S. Davis,et al.  The effect of stabilising agents on the organ distribution of lipid emulsions , 1989 .

[16]  K. Kohn,et al.  Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: evidence for a specific receptor site and a relation to antitumor activity. , 1989, Cancer research.

[17]  R. Müller,et al.  The organ distribution and circulation time of intravenously injected colloidal carriers sterically stabilized with a block copolymer--poloxamine 908. , 1987, Life sciences.

[18]  S. Davis,et al.  Effect of the nonionic surfactant poloxamer 338 on the fate and deposition of polystyrene microspheres following intravenous administration. , 1983, Journal of pharmaceutical sciences.

[19]  A. McPhail,et al.  Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2 , 1966 .

[20]  R. Müller,et al.  Phagocytic uptake and cytotoxicity of solid lipid nanoparticles (SLN) sterically stabilized with poloxamine 908 and poloxamer 407. , 1996, Journal of drug targeting.

[21]  Patrick Couvreur,et al.  Controlled drug delivery with nanoparticles : current possibilities and future trends , 1995 .

[22]  M. Alonso,et al.  Poly(D,L-lactide-co-glycolide) micro and nanospheres as a way to prolong blood/plasma levels of subcutaneously injected cyclosporin A , 1995 .

[23]  R. Müller,et al.  Solid lipid nanoparticles (SLN) : an alternative colloidal carrier system for controlled drug delivery , 1995 .

[24]  D. A. Kharkevich,et al.  Analgesic activity of the hexapeptide dalargin adsorbed on the surface of polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles , 1995 .

[25]  A. E. Ahmed,et al.  Determination of camptothecin in biological fluids using reversed-phase high-performance liquid chromatography with fluorescence detection. , 1990, Journal of chromatography.