Development of a S-adenosylmethionine analog that intrudes the RNA-cap binding site of Zika methyltransferase

[1]  C. Rice,et al.  Identification of a Small Interface between the Methyltransferase and RNA Polymerase of NS5 that is Essential for Zika Virus Replication , 2018, Scientific Reports.

[2]  Joyce V. B. Borba,et al.  The A–Z of Zika drug discovery , 2018, Drug Discovery Today.

[3]  Carolina M. Voloch,et al.  Evidence for Transmission of Zika Virus by Platelet Transfusion , 2017 .

[4]  Andrea Brancale,et al.  Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design. , 2017, European journal of medicinal chemistry.

[5]  R. Jain,et al.  Structures of NS5 Methyltransferase from Zika Virus , 2016, Cell reports.

[6]  M. Diamond,et al.  Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere , 2016, Journal of Virology.

[7]  Anthony S Fauci,et al.  Zika Virus in the Americas--Yet Another Arbovirus Threat. , 2016, The New England journal of medicine.

[8]  T. Huisman,et al.  Evidence of Sexual Transmission of Zika Virus , 2016 .

[9]  L. R. Petersen,et al.  Zika Virus. , 2016, The New England journal of medicine.

[10]  P. Shi,et al.  Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5) , 2015, Proceedings of the National Academy of Sciences.

[11]  Susan A. Jones,et al.  Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase , 2015, PloS one.

[12]  Gérard Bricogne,et al.  Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery. , 2014, Antiviral research.

[13]  K. Fink,et al.  Flavivirus RNA methylation. , 2014, The Journal of general virology.

[14]  Katarzyna H. Kaminska,et al.  Structural analysis of human 2′-O-ribose methyltransferases involved in mRNA cap structure formation , 2014, Nature Communications.

[15]  D. Schnappinger,et al.  Bisubstrate Inhibitors of Biotin Protein Ligase in Mycobacterium tuberculosis Resistant to Cyclonucleoside Formation. , 2013, ACS medicinal chemistry letters.

[16]  David C. Chang,et al.  Correction: Rational Design of a Live Attenuated Dengue Vaccine: 2′-O-Methyltransferase Mutants Are Highly Attenuated and Immunogenic in Mice and Macaques , 2013, PLoS Pathogens.

[17]  Xuping Xie,et al.  Rational Design of a Flavivirus Vaccine by Abolishing Viral RNA 2′-O Methylation , 2013, Journal of Virology.

[18]  B. Geiss,et al.  Identification of a Novel Antiviral Inhibitor of the Flavivirus Guanylyltransferase Enzyme , 2012, Journal of Virology.

[19]  Gang Wang,et al.  Small Molecule Inhibitors That Selectively Block Dengue Virus Methyltransferase* , 2010, The Journal of Biological Chemistry.

[20]  M. Trevethick,et al.  Ligand binding assays at equilibrium: validation and interpretation , 2010, British journal of pharmacology.

[21]  Hongping Dong,et al.  Biochemical and genetic characterization of dengue virus methyltransferase. , 2010, Virology.

[22]  Randy J. Read,et al.  Acta Crystallographica Section D Biological , 2003 .

[23]  Martino Bolognesi,et al.  Flaviviral methyltransferase/RNA interaction: Structural basis for enzyme inhibition , 2009, Antiviral Research.

[24]  Lefteris Angelis,et al.  Validation and interpretation of Web users' sessions clusters , 2007, Inf. Process. Manag..

[25]  Jack Snoeyink,et al.  Nucleic Acids Research Advance Access published April 22, 2007 MolProbity: all-atom contacts and structure validation for proteins and nucleic acids , 2007 .

[26]  Yi Guo,et al.  Structure and Function of Flavivirus NS5 Methyltransferase , 2007, Journal of Virology.

[27]  Yi Guo,et al.  West Nile Virus 5′-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2′-O Methylations by Nonstructural Protein 5 , 2006, Journal of Virology.

[28]  Victor S Lamzin,et al.  Auto-rickshaw: an automated crystal structure determination platform as an efficient tool for the validation of an X-ray diffraction experiment. , 2005, Acta crystallographica. Section D, Biological crystallography.

[29]  Kevin Cowtan,et al.  research papers Acta Crystallographica Section D Biological , 2005 .

[30]  Jean-Louis Romette,et al.  A Structural Basis for the Inhibition of the NS5 Dengue Virus mRNA 2′-O-Methyltransferase Domain by Ribavirin 5′-Triphosphate* , 2004, Journal of Biological Chemistry.

[31]  Z. Otwinowski,et al.  Processing of X-ray diffraction data collected in oscillation mode. , 1997, Methods in enzymology.