A FRET profile of modifications in Estrogen Receptor α associated with resistance to anti-estrogens Submitted 10
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[1] K. Jirström,et al. Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients. , 2006, Journal of the National Cancer Institute.
[2] R. Tsien,et al. The Fluorescent Toolbox for Assessing Protein Location and Function , 2006, Science.
[3] A. Pike. Lessons learnt from structural studies of the oestrogen receptor. , 2006, Best practice & research. Clinical endocrinology & metabolism.
[4] C. J. Barnes,et al. P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation. , 2006, Cancer research.
[5] Robert B Livingston,et al. Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17. , 2005, Journal of the National Cancer Institute.
[6] T. Willson,et al. Structural basis for an unexpected mode of SERM-mediated ER antagonism. , 2005, Molecular cell.
[7] J. Robertson,et al. Endocrine treatment options for advanced breast cancer--the role of fulvestrant. , 2005, European journal of cancer.
[8] M. Castiglione‐Gertsch,et al. The choice of systemic adjuvant therapy in receptor-positive early breast cancer. , 2005, European journal of cancer.
[9] D. McDonnell,et al. The molecular pharmacology of estrogen receptor modulators: implications for the treatment of breast cancer. , 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.
[10] J. Robertson. Selective oestrogen receptor modulators/new antioestrogens: a clinical perspective. , 2004, Cancer treatment reviews.
[11] Vincent Laudet,et al. Principles for modulation of the nuclear receptor superfamily , 2004, Nature Reviews Drug Discovery.
[12] A. Floore,et al. Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer. , 2004, Cancer cell.
[13] D. Vanderwall,et al. Correlation between in vitro peptide binding profiles and cellular activities for estrogen receptor-modulating compounds. , 2004, Molecular endocrinology.
[14] C. Osborne,et al. Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action , 2004, British Journal of Cancer.
[15] J. Robertson,et al. Efficacy of tamoxifen following anastrozole ('Arimidex') compared with anastrozole following tamoxifen as first-line treatment for advanced breast cancer in postmenopausal women. , 2003, European journal of cancer.
[16] R. Agami,et al. The tumor-suppressive functions of the human INK4A locus. , 2003, Cancer cell.
[17] S. Hilsenbeck,et al. Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer. , 2003, Journal of the National Cancer Institute.
[18] F. Lallemand,et al. Involvement of G1/S cyclins in estrogen-independent proliferation of estrogen receptor-positive breast cancer cells , 2002, Oncogene.
[19] R. Bernards,et al. Stable suppression of tumorigenicity by virus-mediated RNA interference. , 2002, Cancer cell.
[20] A. Howell,et al. Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[21] C K Osborne,et al. Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[22] V. Jordan,et al. Molecular classification of selective oestrogen receptor modulators on the basis of gene expression profiles of breast cancer cells expressing oestrogen receptor α , 2002, British Journal of Cancer.
[23] Hong Liu,et al. Re: Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17 beta-estradiol and the two faces of Janus: sex steroids as mediators of both cell proliferation and cell death. , 2002, Journal of the National Cancer Institute.
[24] Patricia A. Dyck,et al. Gene expression profiles with activation of the estrogen receptor alpha-selective estrogen receptor modulator complex in breast cancer cells expressing wild-type estrogen receptor. , 2002, Cancer research.
[25] W. Miller. Regulatory Subunits of PKA and Breast Cancer , 2002, Annals of the New York Academy of Sciences.
[26] D. Bentrem,et al. Effects of a new clinically relevant antiestrogen (GW5638) related to tamoxifen on breast and endometrial cancer growth in vivo. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.
[27] Myles Brown,et al. Molecular Determinants for the Tissue Specificity of SERMs , 2002, Science.
[28] J. Pezzuto,et al. Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models. , 2001, Cancer research.
[29] D. McDonnell,et al. The Human Estrogen Receptor-α Is a Ubiquitinated Protein Whose Stability Is Affected Differentially by Agonists, Antagonists, and Selective Estrogen Receptor Modulators* , 2001, The Journal of Biological Chemistry.
[30] R. Habets,et al. Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer* , 2001, The Journal of Biological Chemistry.
[31] C K Osborne,et al. Selective estrogen receptor modulators: structure, function, and clinical use. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[32] D. Fowlkes,et al. Peptide antagonists of the human estrogen receptor. , 1999, Science.
[33] H. Pols,et al. Distinct effects on the conformation of estrogen receptor alpha and beta by both the antiestrogens ICI 164,384 and ICI 182,780 leading to opposite effects on receptor stability. , 1999, Biochemical and biophysical research communications.
[34] H Grøn,et al. Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[35] David A. Agard,et al. The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen , 1998, Cell.
[36] J. Trowsdale,et al. HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading , 1997, Current Biology.
[37] Zbigniew Dauter,et al. Molecular basis of agonism and antagonism in the oestrogen receptor , 1997, Nature.
[38] D. Picard,et al. Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. , 1996, The EMBO journal.
[39] Daniel Metzger,et al. Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase , 1995, Science.
[40] D. Scherman,et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[41] P. Hordijk,et al. cAMP abrogates the p21ras-mitogen-activated protein kinase pathway in fibroblasts. , 1994, The Journal of biological chemistry.
[42] S. Khosla,et al. Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells. , 2005, Molecular endocrinology.
[43] J. Hartman,et al. Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[44] B. Katzenellenbogen,et al. Allosteric control of ligand selectivity between estrogen receptors alpha and beta: implications for other nuclear receptors. , 2004, Molecular cell.
[45] R. Schiff,et al. Breast cancer endocrine resistance: how growth factor signaling and estrogen receptor coregulators modulate response. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[46] K. Pritchard. Endocrine therapy of advanced disease: analysis and implications of the existing data. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[47] R. Coombes,et al. Phosphorylation of human estrogen receptor alpha by protein kinase A regulates dimerization. , 1999, Molecular and cellular biology.
[48] J. Gustafsson,et al. Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites. , 1997, Science.