Anti-interleukin-6 receptor antibody (MR16-1) promotes muscle regeneration via modulation of gene expressions in infiltrated macrophages.
暂无分享,去创建一个
Y. Ohira | N. Nakai | T. Ohira | R. Fujita | Tsubasa Shibaguchi | N. Nishimoto | F. Kawano
[1] Michael C. Ostrowski,et al. TNF Inhibits Notch-1 in Skeletal Muscle Cells by Ezh2 and DNA Methylation Mediated Repression: Implications in Duchenne Muscular Dystrophy , 2010, PloS one.
[2] H. Okano,et al. Anti-IL-6-receptor antibody promotes repair of spinal cord injury by inducing microglia-dominant inflammation , 2010, Experimental Neurology.
[3] H. Matsubara,et al. Antibody against interleukin-6 receptor attenuates left ventricular remodelling after myocardial infarction in mice. , 2010, Cardiovascular research.
[4] S. Gordon,et al. Alternative activation of macrophages: mechanism and functions. , 2010, Immunity.
[5] W. Grody,et al. Arginine Metabolism by Macrophages Promotes Cardiac and Muscle Fibrosis in mdx Muscular Dystrophy , 2010, PloS one.
[6] Nicolas A. Dumont,et al. Cell Injury , Repair , Aging and Apoptosis Macrophages Protect against Muscle Atrophy and Promote Muscle Recovery in Vivo and in Vitro A Mechanism Partly Dependent on the Insulin-Like Growth Factor-1 Signaling Molecule , 2010 .
[7] J. Tidball,et al. Regulatory interactions between muscle and the immune system during muscle regeneration. , 2010, American journal of physiology. Regulatory, integrative and comparative physiology.
[8] H. Okano,et al. Blockade of interleukin-6 signaling suppressed cochlear inflammatory response and improved hearing impairment in noise-damaged mice cochlea , 2010, Neuroscience Research.
[9] S. Schiaffino,et al. Regeneration of mammalian skeletal muscle. Basic mechanisms and clinical implications. , 2010, Current pharmaceutical design.
[10] N. Rosenthal,et al. A CREB-C/EBPβ cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair , 2009, Proceedings of the National Academy of Sciences.
[11] N. Okiyama,et al. Therapeutic effects of interleukin-6 blockade in a murine model of polymyositis that does not require interleukin-17A. , 2009, Arthritis and rheumatism.
[12] M. Tarnopolsky,et al. Association of Interleukin-6 Signalling with the Muscle Stem Cell Response Following Muscle-Lengthening Contractions in Humans , 2009, PloS one.
[13] L. McManus,et al. Bone marrow-derived cell regulation of skeletal muscle regeneration , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[14] T. Gotoh,et al. Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy. , 2008, Human molecular genetics.
[15] Nicolas A. Dumont,et al. Neutrophil-induced skeletal muscle damage: a calculated and controlled response following hindlimb unloading and reloading. , 2008, American journal of physiology. Regulatory, integrative and comparative physiology.
[16] A. Uezumi,et al. Suppression of macrophage functions impairs skeletal muscle regeneration with severe fibrosis. , 2008, Experimental cell research.
[17] P. Carmeliet,et al. Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathway. , 2008, Genes & development.
[18] T. Shavlakadze,et al. Proceedings of the Australian Physiological Society Symposium: Myopathies and Muscle Regeneration IMPLICATIONS OF CROSS-TALK BETWEEN TUMOUR NECROSIS FACTOR AND INSULIN-LIKE GROWTH FACTOR-1 SIGNALLING IN SKELETAL MUSCLE , 2008 .
[19] G. Fantuzzi,et al. Endogenous interferon-gamma is required for efficient skeletal muscle regeneration. , 2008, American journal of physiology. Cell physiology.
[20] P. Muñoz-Cánoves,et al. Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy. , 2008, Cell metabolism.
[21] N. Van Rooijen,et al. Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis , 2007, The Journal of experimental medicine.
[22] N. Rosenthal,et al. Local expression of IGF‐1 accelerates muscle regeneration by rapidly modulating inflammatory cytokines and chemokines , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[23] Yi-Ping Li,et al. TNF-α regulates myogenesis and muscle regeneration by activating p38 MAPK , 2007 .
[24] J. Tidball,et al. Macrophages promote muscle membrane repair and muscle fibre growth and regeneration during modified muscle loading in mice in vivo , 2007, The Journal of physiology.
[25] S. Gordon,et al. Monocyte and macrophage heterogeneity , 2005, Nature Reviews Immunology.
[26] Yi-Ping Li,et al. Role of TNF-α signaling in regeneration of cardiotoxin-injured muscle , 2005 .
[27] J. Suttles,et al. Macrophages Sequentially Change Their Functional Phenotype in Response to Changes in Microenvironmental Influences1 , 2005, The Journal of Immunology.
[28] D. Cooper,et al. IL-6-induced skeletal muscle atrophy. , 2005, Journal of applied physiology.
[29] J. Tidball. Inflammatory processes in muscle injury and repair. , 2005, American journal of physiology. Regulatory, integrative and comparative physiology.
[30] T. Kishimoto,et al. Inhibition of IL-6 for the treatment of inflammatory diseases. , 2004, Current opinion in pharmacology.
[31] N. Miyasaka,et al. Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial. , 2004, Arthritis and rheumatism.
[32] F. Ali-Osman,et al. Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis , 2004, Oncogene.
[33] T. Shimazaki,et al. Blockade of interleukin‐6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury , 2004, Journal of neuroscience research.
[34] M. Grounds,et al. Anti‐TNFα (Remicade®) therapy protects dystrophic skeletal muscle from necrosis , 2004 .
[35] M. Rudnicki,et al. Cellular and molecular regulation of muscle regeneration. , 2004, Physiological reviews.
[36] Freddie H. Fu,et al. Improvement of muscle healing through enhancement of muscle regeneration and prevention of fibrosis , 2003, Muscle & nerve.
[37] Yoshiki Yamada,et al. Characterization of anti-mouse interleukin-6 receptor antibody. , 2002, Immunology letters.
[38] E. Senba,et al. In Vivo Activation of STAT3 Signaling in Satellite Cells and Myofibers in Regenerating Rat Skeletal Muscles , 2002, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[39] E. Senba,et al. Gene Expression of Receptors for IL-6, LIF, and CNTF in Regenerating Skeletal Muscles , 2000, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[40] T. Kishimoto,et al. Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis. , 1998, Arthritis and rheumatism.
[41] M. Yano,et al. Involvement of interleukin-6 in activation of lysosomal cathepsin and atrophy of muscle fibers induced by intramuscular injection of turpentine oil in mice. , 1997, Journal of biochemistry.
[42] M. Yano,et al. Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice. , 1996, The Journal of clinical investigation.
[43] S. Akira,et al. Cytokine signal transduction , 1994, Cell.