Sequential logic operations with a molecular keypad lock with four inputs and dual fluorescence outputs.

A novel coumarin-rhodamine conjugate was prepared, and its metal binding properties were studied by UV/Vis and fluorescence spectroscopy. The conjugate serves as a ratiometric and highly selective fluorescent sensor for Hg(2+) ions. Its metal-responsive spectral properties were utilized to construct a molecular keypad lock with four inputs and dual fluorescence outputs. The complexity of this molecular logic network can greatly enhance the security level of this device.

[1]  M. Amelia,et al.  Signal processing with multicomponent systems based on metal complexes , 2010 .

[2]  Leila Motiei,et al.  Electrically addressable multistate volatile memory with flip-flop and flip-flap-flop logic circuits on a solid support. , 2010, Angewandte Chemie.

[3]  Lin Yuan,et al.  A highly selective and sensitive fluorescent probe for Hg(2+) imaging in live cells based on a rhodamine-thioamide-alkyne scaffold. , 2010, Chemical communications.

[4]  Fang Pu,et al.  DNA-based logic gates operating as a biomolecular security device. , 2011, Chemical communications.

[5]  Zhiqian Guo,et al.  A multiaddressable photochromic bisthienylethene with sequence-dependent responses: construction of an INHIBIT logic gate and a keypad lock. , 2013, ACS applied materials & interfaces.

[6]  Uwe Pischel,et al.  Molekulare Logik mit Speicherfunktion , 2010 .

[7]  Uwe Pischel,et al.  Smart molecules at work--mimicking advanced logic operations. , 2010, Chemical Society reviews.

[8]  Ming Zhou,et al.  A self-powered and reusable biocomputing security keypad lock system based on biofuel cells. , 2010, Chemistry.

[9]  Uwe Pischel,et al.  Chemical approaches to molecular logic elements for addition and subtraction. , 2007, Angewandte Chemie.

[10]  A. Shanzer,et al.  A molecular full-adder and full-subtractor, an additional step toward a moleculator. , 2006, Journal of the American Chemical Society.

[11]  Elizabeth M. Nolan,et al.  Tools and tactics for the optical detection of mercuric ion. , 2008, Chemical reviews.

[12]  A. P. Silva,et al.  From Complexation to Computation: Recent Progress in Molecular Logic , 2007 .

[13]  A. Singh,et al.  Fluorescent zinc(II) complex exhibiting "on-off-on" switching toward Cu2+ and Ag+ ions. , 2011, Inorganic chemistry.

[14]  Amitava Das,et al.  A simple chemosensor for Hg2+ and Cu2+ that works as a molecular keypad lock. , 2008, Chemical communications.

[15]  A. P. de Silva,et al.  Molecular-scale logic gates. , 2004, Chemistry.

[16]  Jan Halámek,et al.  Self-powered biomolecular keypad lock security system based on a biofuel cell. , 2010, Chemical communications.

[17]  Manoj Kumar,et al.  A reversible fluorescent Hg2+/K+ switch that works as keypad lock in the presence of F- ion. , 2009, Chemical communications.

[18]  M. Devi,et al.  Au microparticles mediated construction of a logic based dual channel molecular keypad lock. , 2013, Dalton transactions.

[19]  A. P. de Silva,et al.  Molecular logic and computing. , 2007, Nature nanotechnology.

[20]  E. Katz,et al.  Biocomputing security system: concatenated enzyme-based logic gates operating as a biomolecular keypad lock. , 2008, Journal of the American Chemical Society.

[21]  Manoj Kumar,et al.  A molecular keypad lock based on the thiacalix[4]arene of 1,3-alternate conformation. , 2009, Organic letters.

[22]  Jianzhong Shen,et al.  Ordered self-assembly of proteins for computation in mammalian cells. , 2014, Chemical communications.

[23]  Wei Jiang,et al.  A double plug-socket system capable of molecular keypad locks through controllable photooxidation. , 2009, Chemistry.

[24]  Graham de Ruiter,et al.  Sequential logic operations with surface-confined polypyridyl complexes displaying molecular random access memory features. , 2010, Angewandte Chemie.

[25]  Jan Halámek,et al.  Keypad Lock Security System Based on Immune-Affinity Recognition Integrated with a Switchable Biofuel Cell , 2010 .

[26]  He Tian,et al.  Data processing on a unimolecular platform. , 2010, Angewandte Chemie.

[27]  Xiaogang Qu,et al.  Nucleic acid-mesoporous silica nanoparticle conjugates for keypad lock security operation. , 2013, Chemical communications.

[28]  Galina Melman,et al.  A molecular keypad lock: a photochemical device capable of authorizing password entries. , 2007, Journal of the American Chemical Society.

[29]  H. Tian,et al.  A fluorophore capable of crossword puzzles and logic memory. , 2007, Angewandte Chemie.

[30]  S. Dong,et al.  DNA-templated Ag nanoclusters as signal transducers for a label-free and resettable keypad lock. , 2013, Chemical communications.

[31]  Bernard Valeur,et al.  Ion-responsive fluorescent compounds. 4. Effect of cation binding on the photophysical properties of a coumarin linked to monoaza- and diaza-crown ethers , 1993 .

[32]  Xiaogang Qu,et al.  Versatile logic devices based on programmable DNA-regulated silver-nanocluster signal transducers. , 2012, Chemistry.

[33]  Joakim Andréasson,et al.  An all-photonic molecular keypad lock. , 2009, Chemistry.

[34]  Manoj Kumar,et al.  A naphthalimide based chemosensor for Zn2+, pyrophosphate and H2O2: sequential logic operations at the molecular level. , 2013, Chemical communications.

[35]  He Tian,et al.  Datenverarbeitung mit einzelnen Molekülen , 2010 .

[36]  Wei-Chuan Sun,et al.  A fluorescent-switch-based computing platform in defending information risk. , 2008, Chemistry.

[37]  David Margulies,et al.  Fluorescein as a model molecular calculator with reset capability , 2005, Nature materials.

[38]  Leila Motiei,et al.  Authorizing multiple chemical passwords by a combinatorial molecular keypad lock. , 2013, Journal of the American Chemical Society.

[39]  A. Prasanna de Silva.  Molecular Logic Gate Arrays , 2011 .

[40]  Yan Du,et al.  A DNA-based and electrochemically transduced keypad lock system with reset function. , 2012, Chemistry.

[41]  Injae Shin,et al.  In vivo monitoring of mercury ions using a rhodamine-based molecular probe. , 2006, Journal of the American Chemical Society.

[42]  He Tian,et al.  Unsymmetrical diarylethenes as molecular keypad locks with tunable photochromism and fluorescence via Cu2+ and CN- coordinations. , 2012, Chemical communications.

[43]  Uwe Pischel,et al.  Chemische Strategien für den Aufbau molekularer Logikelemente zur Addition und Subtraktion , 2007 .

[44]  Uwe Pischel,et al.  Advanced molecular logic with memory function. , 2010, Angewandte Chemie.

[45]  Jing Li,et al.  An aptamer-based keypad lock system. , 2012, Chemical communications.

[46]  He Tian,et al.  Quantitative photoswitching in bis(dithiazole)ethene enables modulation of light for encoding optical signals. , 2014, Angewandte Chemie.

[47]  Shaojun Dong,et al.  A visible multi-digit DNA keypad lock based on split G-quadruplex DNAzyme and silver microspheres. , 2013, Chemical communications.

[48]  J. Fraser Stoddart,et al.  Computing at the Molecular Level , 2001 .