An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture.
暂无分享,去创建一个
A. Plückthun | P. Ernst | A. Lupas | Hongbo Zhu | M. Coles | M. Hartmann | M. ElGamacy | Patrick Ernst
[1] A. Plückthun,et al. Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts , 2019, Scientific Reports.
[2] Andreas Plückthun,et al. Rigidly connected multispecific artificial binders with adjustable geometries , 2017, Scientific Reports.
[3] Po-Ssu Huang,et al. Designing repeat proteins: a modular approach to protein design. , 2017, Current opinion in structural biology.
[4] 周阳,et al. Folding and unfolding mechanism , 2017 .
[5] D. Baker,et al. The coming of age of de novo protein design , 2016, Nature.
[6] B. Kuhlman,et al. Design of structurally distinct proteins using strategies inspired by evolution , 2016, Science.
[7] Liisa Holm,et al. Dali server update , 2016, Nucleic Acids Res..
[8] A. Plückthun,et al. DARPin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography. , 2016, Journal of molecular biology.
[9] David Baker,et al. Rational design of alpha-helical tandem repeat proteins with closed architectures , 2015, Nature.
[10] David Baker,et al. Exploring the repeat protein universe through computational protein design , 2015, Nature.
[11] Albert Perez-Riba,et al. Dissecting and reprogramming the folding and assembly of tandem-repeat proteins. , 2015, Biochemical Society transactions.
[12] Andrew R Thomson,et al. De novo protein design: how do we expand into the universe of possible protein structures? , 2015, Current opinion in structural biology.
[13] David Baker,et al. A general computational approach for repeat protein design. , 2015, Journal of molecular biology.
[14] Andreas Plückthun,et al. Designed ankyrin repeat proteins (DARPins): binding proteins for research, diagnostics, and therapy. , 2015, Annual review of pharmacology and toxicology.
[15] David Baker,et al. Control of repeat protein curvature by computational protein design , 2014, Nature Structural &Molecular Biology.
[16] P. Bradley,et al. Rational design of α-helical tandem repeat proteins with closed architectures , 2015 .
[17] Yuxing Liao,et al. ECOD: An Evolutionary Classification of Protein Domains , 2014, PLoS Comput. Biol..
[18] Jack Snoeyink,et al. Scientific benchmarks for guiding macromolecular energy function improvement. , 2013, Methods in enzymology.
[19] Alexander D. MacKerell,et al. Optimization of the additive CHARMM all-atom protein force field targeting improved sampling of the backbone φ, ψ and side-chain χ(1) and χ(2) dihedral angles. , 2012, Journal of chemical theory and computation.
[20] B. Kuhlman,et al. Increasing sequence diversity with flexible backbone protein design: the complete redesign of a protein hydrophobic core. , 2012, Structure.
[21] J. García de la Torre,et al. Prediction of hydrodynamic and other solution properties of rigid proteins from atomic- and residue-level models. , 2011, Biophysical journal.
[22] Jens Meiler,et al. RosettaScripts: A Scripting Language Interface to the Rosetta Macromolecular Modeling Suite , 2011, PloS one.
[23] Serdar Kuyucak,et al. Accurate determination of the binding free energy for KcsA-charybdotoxin complex from the potential of mean force calculations with restraints. , 2011, Biophysical journal.
[24] Z. Weng,et al. A structure‐based benchmark for protein–protein binding affinity , 2011, Protein science : a publication of the Protein Society.
[25] A. Plückthun,et al. Residue-resolved stability of full-consensus ankyrin repeat proteins probed by NMR. , 2010, Journal of molecular biology.
[26] Randy J. Read,et al. Acta Crystallographica Section D Biological , 2003 .
[27] David E. Kim,et al. Sampling bottlenecks in de novo protein structure prediction. , 2009, Journal of molecular biology.
[28] D. Baker,et al. RosettaHoles: Rapid assessment of protein core packing for structure prediction, refinement, design, and validation , 2008, Protein science : a publication of the Protein Society.
[29] Colin A. Smith,et al. Backrub-like backbone simulation recapitulates natural protein conformational variability and improves mutant side-chain prediction. , 2008, Journal of molecular biology.
[30] Andreas Plückthun,et al. Designed armadillo repeat proteins as general peptide-binding scaffolds: consensus design and computational optimization of the hydrophobic core. , 2008, Journal of molecular biology.
[31] Andreas Plückthun,et al. Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins. , 2008, Journal of molecular biology.
[32] Jean-François Guichou,et al. Structural basis for the interaction between focal adhesion kinase and CD4. , 2008, Journal of molecular biology.
[33] Doug Barrick,et al. Repeat-protein folding: new insights into origins of cooperativity, stability, and topology. , 2008, Archives of biochemistry and biophysics.
[34] Alan R Lowe,et al. Rational redesign of the folding pathway of a modular protein , 2007, Proceedings of the National Academy of Sciences.
[35] Laxmikant V. Kalé,et al. Scalable molecular dynamics with NAMD , 2005, J. Comput. Chem..
[36] Tommi Kajander,et al. A new folding paradigm for repeat proteins. , 2005, Journal of the American Chemical Society.
[37] F. Studier,et al. Protein production by auto-induction in high density shaking cultures. , 2005, Protein expression and purification.
[38] J. Skolnick,et al. TM-align: a protein structure alignment algorithm based on the TM-score , 2005, Nucleic acids research.
[39] Kevin Cowtan,et al. research papers Acta Crystallographica Section D Biological , 2005 .
[40] K Henrick,et al. Electronic Reprint Biological Crystallography Secondary-structure Matching (ssm), a New Tool for Fast Protein Structure Alignment in Three Dimensions Biological Crystallography Secondary-structure Matching (ssm), a New Tool for Fast Protein Structure Alignment in Three Dimensions , 2022 .
[41] Doug Barrick,et al. An experimentally determined protein folding energy landscape. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[42] Andreas Plückthun,et al. Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins. , 2003, Journal of molecular biology.
[43] Sophie E Jackson,et al. The folding and design of repeat proteins: reaching a consensus. , 2003, Current opinion in structural biology.
[44] S. Wodak,et al. Assessment of blind predictions of protein–protein interactions: Current status of docking methods , 2003, Proteins.
[45] J. Stock,et al. Crystal Structure of the CheA Histidine Phosphotransfer Domain that Mediates Response Regulator Phosphorylation in Bacterial Chemotaxis* , 2001, The Journal of Biological Chemistry.
[46] A Vagin,et al. An approach to multi-copy search in molecular replacement. , 2000, Acta crystallographica. Section D, Biological crystallography.
[47] B. Kobe,et al. When protein folding is simplified to protein coiling: the continuum of solenoid protein structures. , 2000, Trends in biochemical sciences.
[48] H. Kessler,et al. An efficient strategy for assignment of cross-peaks in 3D heteronuclear NOESY experiments , 1999, Journal of biomolecular NMR.
[49] K. Wilson,et al. Efficient anisotropic refinement of macromolecular structures using FFT. , 1999, Acta crystallographica. Section D, Biological crystallography.
[50] Wolfgang Kabsch,et al. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants , 1993 .
[51] J. Szulmajster. Protein folding , 1988, Bioscience reports.
[52] W. Wooster,et al. Crystal structure of , 2005 .