Induction of ventricular tachycardia during programmed electrical stimulation: analysis of pacing methods.

THE METHOD of serial electrophysiologic drug testing has been used with increasing frequency to enhance predictive accuracy of drug therapy in patients with ventricular tachycardia' and cardiac arrest.5'According to this method, patients are brought before drug treatment to the electrophysiology laboratory, where electrode catheters are positioned at multiple areas of the heart and programmed electrical stimulation is used to initiate ventricular tachycardia. '0 After the initial study, drugs are administered to the patient and programmed electrical stimulation is repeated. Obviously, use of this method depends on induction of ventricular tachycardia at the initial study, which is not possible in every patient." 1 2The purpose of this article is twofold: (1) to analyze the effect of stimulation technique, pacing cycle length, and type of heart disease on induction of ventricular tachycardia in 329 consecutively studied patients with a history of sustained ventricular tachycardia. nonsustained ventricular tachycardia, and cardiac arrest, and (2) to present an overview of methods used to induce ventricular tachycardia.

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