In Vitro Ovarian Model Systems

[1]  R. Reig-Viader,et al.  Gene expression is altered after bisphenol A exposure in human fetal oocytes in vitro. , 2012, Molecular human reproduction.

[2]  P. Robles,et al.  Human meiotic progression and recombination are affected by Bisphenol A exposure during in vitro human oocyte development. , 2011, Human reproduction.

[3]  Robson A. S. Santos,et al.  Angiotensin‐(1–7) induces ovulation and steroidogenesis in perfused rabbit ovaries , 2011, Experimental physiology.

[4]  P. Devine,et al.  Detection of DNA damage in oocytes of small ovarian follicles following phosphoramide mustard exposures of cultured rodent ovaries in vitro. , 2011, Toxicology and applied pharmacology.

[5]  Rupesh K. Gupta,et al.  The Ability of the Aryl Hydrocarbon Receptor to Regulate Ovarian Follicle Growth and Estradiol Biosynthesis in Mice Depends on Stage of Sexual Maturity1 , 2010, Biology of reproduction.

[6]  Rupesh K. Gupta,et al.  Di-(2-ethylhexyl) phthalate and mono-(2-ethylhexyl) phthalate inhibit growth and reduce estradiol levels of antral follicles in vitro. , 2010, Toxicology and applied pharmacology.

[7]  R. Hutz,et al.  Gold nanoparticles enter rat ovarian granulosa cells and subcellular organelles, and alter in-vitro estrogen accumulation. , 2009, The Journal of reproduction and development.

[8]  I. Hernández-Ochoa,et al.  The role of the aryl hydrocarbon receptor in the female reproductive system. , 2009, Biochemical pharmacology.

[9]  Wen-chang Zhang,et al.  Cadmium exerts toxic effects on ovarian steroid hormone release in rats. , 2008, Toxicology letters.

[10]  S. Hernández-Díaz,et al.  Medications as a Potential Source of Exposure to Phthalates in the U.S. Population , 2008, Environmental health perspectives.

[11]  R. Cortvrindt,et al.  Timing of nuclear maturation and postovulatory aging in oocytes of in vitro-grown mouse follicles with or without oil overlay. , 2008, Biology of reproduction.

[12]  R. Cortvrindt,et al.  The antibiotic streptomycin assessed in a battery of in vitro tests for reproductive toxicology. , 2007, Toxicology in vitro : an international journal published in association with BIBRA.

[13]  R. Newbold,et al.  Estradiol, progesterone, and genistein inhibit oocyte nest breakdown and primordial follicle assembly in the neonatal mouse ovary in vitro and in vivo. , 2007, Endocrinology.

[14]  U. Luderer,et al.  Cyclophosphamide-induced apoptosis in COV434 human granulosa cells involves oxidative stress and glutathione depletion. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.

[15]  A. Aigner.  Applications of RNA interference: current state and prospects for siRNA-based strategies in vivo , 2007, Applied Microbiology and Biotechnology.

[16]  P. Kuhn,et al.  Early postnatal methoxychlor exposure inhibits folliculogenesis and stimulates anti-Mullerian hormone production in the rat ovary. , 2006, The Journal of endocrinology.

[17]  M. Pepling,et al.  From primordial germ cell to primordial follicle: mammalian female germ cell development , 2006, Genesis.

[18]  M. Uzumcu,et al.  The methoxychlor metabolite, 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane, inhibits steroidogenesis in rat ovarian granulosa cells in vitro. , 2006, Reproductive toxicology.

[19]  P. Devine,et al.  Characterizing the ovotoxicity of cyclophosphamide metabolites on cultured mouse ovaries. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.

[20]  M. Skinner.  Regulation of primordial follicle assembly and development. , 2005, Human reproduction update.

[21]  Y. Englert,et al.  Impact of various endocrine and paracrine factors on in vitro culture of preantral follicles in rodents. , 2005, Reproduction.

[22]  George Daston,et al.  The Effects of Chemicals on Mammalian Fertility , 2005, Alternatives to laboratory animals : ATLA.

[23]  R. Cortvrindt,et al.  Ovarian follicle bioassay reveals adverse effects of diazepam exposure upon follicle development and oocyte quality. , 2005, Reproductive toxicology.

[24]  J. Vankerkom,et al.  Cytogenetic studies in mouse oocytes irradiated in vitro at different stages of maturation, by use of an early preantral follicle culture system. , 2005, Mutation research.

[25]  B. Hales,et al.  Impact of paternal exposure to chemotherapy on offspring in the rat. , 2005, Journal of the National Cancer Institute. Monographs.

[26]  W. Rainey,et al.  Ovarian granulosa cell lines , 2004, Molecular and Cellular Endocrinology.

[27]  P. Hoyer,et al.  Initiation of delayed ovotoxicity by in vitro and in vivo exposures of rat ovaries to 4-vinylcyclohexene diepoxide. , 2004, Reproductive toxicology.

[28]  E. Simpson,et al.  Estrogen Actions on Follicle Formation and Early Follicle Development1 , 2004 .

[29]  M. Sahmi,et al.  Expression of 17β- and 3β-hydroxysteroid dehydrogenases and steroidogenic acute regulatory protein in non-luteinizing bovine granulosa cells in vitro , 2004, Molecular and Cellular Endocrinology.

[30]  B. Dutrillaux,et al.  γ-H2AX Expression Pattern in Non-Irradiated Neonatal Mouse Germ Cells and after Low-Dose γ-Radiation: Relationships Between Chromatid Breaks and DNA Double-Strand Breaks1 , 2004 .

[31]  R. Cortvrindt,et al.  Differential FSH exposure in preantral follicle culture has marked effects on folliculogenesis and oocyte developmental competence. , 2004, Human reproduction.

[32]  M. Skinner,et al.  Regulation of ovarian primordial follicle assembly and development by estrogen and progesterone: endocrine model of follicle assembly. , 2003, Endocrinology.

[33]  T. Lovekamp-Swan,et al.  Dual activation of PPARα and PPARγ by mono-(2-ethylhexyl) phthalate in rat ovarian granulosa cells , 2003, Molecular and Cellular Endocrinology.

[34]  T. Lovekamp-Swan,et al.  Mechanisms of phthalate ester toxicity in the female reproductive system. , 2002, Environmental health perspectives.

[35]  P. Hoyer,et al.  Characterization of a rat in vitro ovarian culture system to study the ovarian toxicant 4-vinylcyclohexene diepoxide. , 2002, Toxicology and applied pharmacology.

[36]  K. Korach,et al.  Neonatal Exposure to Genistein Induces Estrogen Receptor (ER)α Expression and Multioocyte Follicles in the Maturing Mouse Ovary: Evidence for ERβ-Mediated and Nonestrogenic Actions , 2002, Biology of reproduction.

[37]  B. Foy,et al.  Effect of cadmium on bromosulfophthalein kinetics in the isolated perfused rat liver system. , 2002, Toxicological sciences : an official journal of the Society of Toxicology.

[38]  M. Skinner,et al.  Insulin but not insulin-like growth factor-1 promotes the primordial to primary follicle transition , 2002, Molecular and Cellular Endocrinology.

[39]  B. Tsang,et al.  Involvement of Transforming Growth Factor α in the Regulation of Rat Ovarian X-Linked Inhibitor of Apoptosis Protein Expression and Follicular Growth by Follicle-Stimulating Hormone1 , 2002, Biology of reproduction.

[40]  R. Cortvrindt,et al.  Follicle culture in reproductive toxicology: a tool for in-vitro testing of ovarian function? , 2002, Human reproduction update.

[41]  E. Rogakou,et al.  Histone H2A variants H2AX and H2AZ. , 2002, Current opinion in genetics & development.

[42]  R. Cortvrindt,et al.  Effects of aromatase inhibition on in vitro follicle and oocyte development analyzed by early preantral mouse follicle culture , 2002, Molecular reproduction and development.

[43]  Tomomi Sato,et al.  Developmental effects of perinatal exposure to bisphenol-A and diethylstilbestrol on reproductive organs in female mice. , 2002, Reproductive toxicology.

[44]  M. Skinner,et al.  Leukemia inhibitory factor (LIF) promotes the primordial to primary follicle transition in rat ovaries , 2002, Molecular and Cellular Endocrinology.

[45]  P. Chedrese,et al.  The diverse mechanism of action of dichlorodiphenyldichloroethylene (DDE) and methoxychlor in ovarian cells in vitro. , 2001, Reproductive toxicology.

[46]  M. Meissler,et al.  The isolated perfused liver. a new model using autologous blood and porcine slaughterhouse organs. , 2001, Journal of pharmacological and toxicological methods.

[47]  M. Skinner,et al.  Basic fibroblast growth factor induces primordial follicle development and initiates folliculogenesis , 2001, Molecular and Cellular Endocrinology.

[48]  R. van den Hurk,et al.  Primate and bovine immature oocytes and follicles as sources of fertilizable oocytes. , 2000, Human reproduction update.

[49]  M. Fukushima,et al.  The history, mechanism and clinical use of oral 5-fluorouracil derivative chemotherapeutic agents. , 2000, Current pharmaceutical biotechnology.

[50]  V. Yamazaki,et al.  A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage , 2000, Current Biology.

[51]  A. Mclaren,et al.  Germ and somatic cell lineages in the developing gonad , 2000, Molecular and Cellular Endocrinology.

[52]  Philip Smith,et al.  Growth and paracrine factors regulating follicular formation and cellular function , 2000, Molecular and Cellular Endocrinology.

[53]  E. Rogakou,et al.  Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo , 1999, The Journal of cell biology.

[54]  M. Skinner,et al.  Kit-Ligand/Stem Cell Factor Induces Primordial Follicle Development and Initiates Folliculogenesis1. , 1999, Endocrinology.

[55]  Colvin Om.  An overview of cyclophosphamide development and clinical applications. , 1999 .

[56]  J. Liu,et al.  Timed analysis of the nuclear maturation of oocytes in early preantral mouse follicle culture supplemented with recombinant gonadotropin. , 1998, Fertility and sterility.

[57]  D. Villeneuve,et al.  The effect of photomirex on the in vitro perfused ovary of the rat. , 1998, Reproductive toxicology.

[58]  E. Rogakou,et al.  DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139* , 1998, The Journal of Biological Chemistry.

[59]  R. Cortvrindt,et al.  Early preantral mouse follicle in vitro maturation: oocyte growth, meiotic maturation and granulosa-cell proliferation. , 1998, Theriogenology.

[60]  James J. Chen,et al.  Influence of sampling on the reproducibility of ovarian follicle counts in mouse toxicity studies. , 1997, Reproductive toxicology.

[61]  G. Hartshorne,et al.  In vitro culture of ovarian follicles. , 1997, Reviews of reproduction.

[62]  R. Cortvrindt,et al.  Assessment of the need for follicle stimulating hormone in early preantral mouse follicle culture in vitro. , 1997, Human reproduction.

[63]  R. Cortvrindt,et al.  In-vitro maturation, fertilization and embryo development of immature oocytes from early preantral follicles from prepuberal mice in a simplified culture system. , 1996, Human reproduction.

[64]  S. Roy,et al.  Methods of separation and in-vitro culture of pre-antral follicles from mammalian ovaries. , 1996, Human reproduction update.

[65]  C. Orton,et al.  Is radiation-induced ovarian failure in rhesus monkeys preventable by luteinizing hormone-releasing hormone agonists?: Preliminary observations. , 1995, The Journal of clinical endocrinology and metabolism.

[66]  L. Povirk,et al.  DNA damage and mutagenesis induced by nitrogen mustards. , 1994, Mutation research.

[67]  D. Villeneuve,et al.  Contamination of human ovarian follicular fluid and serum by chlorinated organic compounds in three Canadian cities. , 1993, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[68]  D. Mattison,et al.  Phosphoramide mustard is responsible for the ovarian toxicity of cyclophosphamide. , 1991, Toxicology and applied pharmacology.

[69]  E. Anderson,et al.  Heterogeneity in granulosa cells of developing rat follicles , 1991, The Anatomical record.

[70]  Y. Uesugi,et al.  Polyovular follicles in mouse ovaries exposed neonatally to diethylstilbestrol in vivo and in vitro. , 1990, Biology of reproduction.

[71]  M. Brännström,et al.  Inhibitors of lipoxygenase increase the ovulation rate in the in-vitro perfused luteinizing hormone-stimulated rabbit ovary. , 1990, Acta physiologica Scandinavica.

[72]  M. Brännström,et al.  Characterization of an in vitro perfused rat ovary model: ovulation rate, oocyte maturation, steroidogenesis and influence of PMSG priming. , 1987, Acta physiologica Scandinavica.

[73]  H. Bern,et al.  Frequent occurrence of polyovular follicles in ovaries of mice exposed neonatally to diethylstilbestrol. , 1986, Teratology.

[74]  T. Curry,et al.  Ovulations in rat ovaries perfused in vitro with follicle-stimulating hormone. , 1985, Biology of reproduction.

[75]  W. LeMaire,et al.  A luteinizing hormone-releasing hormone agonist for the prevention of chemotherapy-induced ovarian follicular loss in rats. , 1985, Cancer research.

[76]  J. Peluso,et al.  Follicular development, steroidogenesis and ovulation within ovaries exposed in vitro to hormone levels which mimic those of the rat estrous cycle. , 1983, Biology of reproduction.

[77]  G. Le Fur,et al.  Peripheral benzodiazepine binding sites: effect of PK 11195, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide. I. In vitro studies. , 1983, Life sciences.

[78]  Y. Moon,et al.  Luteinization of bovine granulosa cells and corpus luteum formation associated with loss of androgen-aromatizing ability. , 1979, Journal of reproduction and fertility.

[79]  H. Koyama,et al.  Cyclophosphamide‐induced ovarian failure and its therapeutic significance in patients with breast cancer , 1977, Cancer.

[80]  T. Pedersen,et al.  Proposal for a classification of oocytes and follicles in the mouse ovary. , 1968, Journal of reproduction and fertility.

[81]  D. Schlessinger,et al.  Mechanism of action of streptomycin in E. coli: interruption of the ribosome cycle at the initiation of protein synthesis. , 1968, Proceedings of the National Academy of Sciences of the United States of America.

[82]  D. Pavic.  THE EFFECT OF GONADOTROPHIC HORMONES ON YOUNG RAT OVARIES GROWN IN ORGAN CULTURE. , 1963, The Journal of endocrinology.

[83]  W. Russell,et al.  The Principles of Humane Experimental Technique , 1960 .

[84]  M. Z. Khan,et al.  Toxic effects of cypermethrin and methamidophos on bovine corpus luteal cells and progesterone production. , 2011, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

[85]  Rupesh K. Gupta,et al.  Bisphenol A impairs follicle growth, inhibits steroidogenesis, and downregulates rate-limiting enzymes in the estradiol biosynthesis pathway. , 2011, Toxicological sciences : an official journal of the Society of Toxicology.

[86]  P. Hoyer,et al.  Reproductive and endocrine toxicology , 2010 .

[87]  P. Hoyer,et al.  Current methods in investigating the development of the female reproductive system. , 2009, Methods in molecular biology.

[88]  R. Cortvrindt,et al.  In vitro effects of dexamethasone on mouse ovarian function and pre-implantation embryo development. , 2007, Reproductive toxicology.

[89]  R. Newbold,et al.  Neonatal Genistein Treatment Alters Ovarian Differentiation in the Mouse: Inhibition of Oocyte Nest Breakdown and Increased Oocyte Survival1 , 2006, Biology of reproduction.

[90]  R. Van den Broecke,et al.  Live Offspring by In Vitro Fertilization of Oocytes from Cryopreserved Primordial Mouse Follicles after Sequential In Vivo Transplantation and In Vitro Maturation1 , 2001, Biology of reproduction.

[91]  T. Huang,et al.  Dexamethasone Inhibits Luteinizing Hormone-Induced Synthesis of Steroidogenic Acute Regulatory Protein in Cultured Rat Preovulatory Follicles1 , 2001, Biology of reproduction.

[92]  N. Spears,et al.  Follicular Development In Vitro , 2000, Seminars in reproductive medicine.

[93]  D. Villeneuve,et al.  Toxicity testing using the isolated in vitro perfused ovary. , 1993, Reproductive toxicology.

[94]  A N Hirshfield,et al.  Development of follicles in the mammalian ovary. , 1991, International review of cytology.

[95]  D. Mattison,et al.  Comparison of random and serial sections in assessment of ovarian toxicity. , 1991, Reproductive toxicology.

[96]  J. Jarrell,et al.  The short-term reproductive toxicity of cyclophosphamide in the female rat. , 1991, Reproductive toxicology.

[97]  R. Williams,et al.  Williams Textbook of endocrinology , 1985 .

[98]  R. Chapman.  Gonadal injury resulting from chemotherapy. , 1983, American journal of industrial medicine.

[99]  R. Dobson,et al.  Female germ cell loss from radiation and chemical exposures. , 1983, American journal of industrial medicine.

[100]  R. Pedersen,et al.  Radiation- and drug-induced DNA repair in mammalian oocytes and embryos. , 1980, Basic life sciences.

[101]  W. Generoso.  Repair in fertilized eggs of mice and its role in the production of chromosomal aberrations. , 1980, Basic life sciences.

[102]  T. G. Baker,et al.  The effects of X-irradiation on mammalian oocytes in organ culture , 1969, Biophysik.