Further evidence for close linkage of the Hb-beta and Hb-delta loci in man.

Nine kindreds have been reported previously which give evidence concerning the linkage relationships of the determinants of the ,B and 8 chains of human haemoglobin. We wish to document a tenth kindred in which, and 8 chain variants are segregating. The fact that no crossovers were observed among 8 offspring of a doubly heterozygous male provides further confirmation of the existing evidence for close linkage of thea and 8 loci.