Automatic Assessment of Cardiac Artery Disease by Using DCAD Module

In patients with cardiac artery disease myocardial perfusion scan, which is a non-invasive method, is utilized. This study is conducted to achieve an advantageous software applicable to quantitative myocardial SPECT perfusion. Each cross-section of the left ventricle is segmented by applying fuzzy clustering method. After obtaining the myocardial skeleton of the left ventricle from its short axis cross sections, we make use of fuzzy logic to decide whether the pixel belongs to myocardial muscle and any perfusion perturbation or not. Abnormal critical conditions in rest and stress studies and coronary artery disease diagnosis were investigated in a set of about 200 images. Measurement and allocation of different myocardial sectors to specific coronary arteries were accomplished by utilizing collected information about respectively 75 patient men and 62 patient women, and the validity of artery obstruction diagnosis has been proved in 40 patients having been under the coronary angiography. We named the achieved software DCAD(b) which has demonstrated a considerably good performance in coronary artery occlusion diagnosis and would be a promising method aiding nuclear medicine specialists in diagnosing these defections.

[1]  J M Bland,et al.  Statistical methods for assessing agreement between two methods of clinical measurement , 1986 .

[2]  C D Cooke,et al.  Diagnostic performance of an expert system for the interpretation of myocardial perfusion SPECT studies. , 2001, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[3]  W. E. Hartnett,et al.  Shape Recognition, Prairie Fires, Convex Deficiencies and Skeletons , 1968 .

[4]  Jean Serra,et al.  Image Analysis and Mathematical Morphology , 1983 .

[5]  Jean Ponsonnaille,et al.  Preliminary evaluation of a fuzzy logic-based automatic quantitative analysis in myocardial SPECT. , 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[6]  Fuzzy logic for the segmentation of myocardial tomoscintigraphic images , 1996, Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[7]  C. V. Jawahar,et al.  Investigations on fuzzy thresholding based on fuzzy clustering , 1997, Pattern Recognit..

[8]  D. Berman,et al.  Quantitative same-day rest-stress technetium-99m-sestamibi SPECT: definition and validation of stress normal limits and criteria for abnormality. , 1993, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[9]  P J Slomka,et al.  Automated alignment and sizing of myocardial stress and rest scans to three-dimensional normal templates using an image registration algorithm. , 1995, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.