IGFBP-2 acts as a tumour suppressor and plays a role in determining chemosensitivity in bladder cancer cells
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D. Gillatt | E. Rowe | J. Holly | C. Perks | A. Koupparis | Zhen Tang
[1] D. McConkey,et al. ERCC2 Mutation: The Marker for Chemosensitivity in Primary and Secondary Muscle-invasive Bladder Cancers. , 2019, European urology.
[2] J. Holly,et al. Inhibition of FASN and ERα signalling during hyperglycaemia-induced matrix-specific EMT promotes breast cancer cell invasion via a caveolin-1-dependent mechanism , 2018, Cancer letters.
[3] P. Wei,et al. IGFBP2 plays an important role in heat shock protein 27-mediated cancer progression and metastasis , 2017, Oncotarget.
[4] Wei Zhang,et al. IGFBP2 Activates the NF-κB Pathway to Drive Epithelial-Mesenchymal Transition and Invasive Character in Pancreatic Ductal Adenocarcinoma. , 2016, Cancer research.
[5] J. Vadgama,et al. Epithelial-Mesenchymal Transition and Breast Cancer , 2016, Journal of clinical medicine.
[6] Dong Wang,et al. Inhibition of IGFBP-2 improves the sensitivity of bladder cancer cells to cisplatin via upregulating the expression of maspin. , 2015, International journal of molecular medicine.
[7] C. Wheeler,et al. HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion in Organotypic Cultures , 2015, PLoS pathogens.
[8] A. Wu,et al. Exogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin β1-ERK pathway , 2014, British Journal of Cancer.
[9] M. Knowles,et al. Molecular biology of bladder cancer: new insights into pathogenesis and clinical diversity , 2014, Nature Reviews Cancer.
[10] C. Zhang,et al. IGF binding protein 2 is a cell-autonomous factor supporting survival and migration of acute leukemia cells , 2013, Journal of Hematology & Oncology.
[11] D. Gillatt,et al. Hyperglycaemia-induced chemoresistance of prostate cancer cells due to IGFBP2. , 2013, Endocrine-related cancer.
[12] L. Zeng,et al. Insulin-like growth factor binding protein-3 (IGFBP-3) plays a role in the anti-tumorigenic effects of 5-Aza-2'-deoxycytidine (AZA) in breast cancer cells. , 2013, Experimental cell research.
[13] L. Zeng,et al. Insulin-like growth factor binding protein 2 (IGFBP-2) promotes growth and survival of breast epithelial cells: novel regulation of the estrogen receptor. , 2013, Endocrinology.
[14] C. Lim,et al. Tumor dissemination: an EMT affair. , 2013, Cancer cell.
[15] J. Holly,et al. Insulin-like growth factor physiology: what we have learned from human studies. , 2012, Endocrinology and metabolism clinics of North America.
[16] Kamaleshwar P Singh,et al. DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells. , 2012, Cancer letters.
[17] D. Gillatt,et al. Insulin-like growth factor-binding protein-2 promotes prostate cancer cell growth via IGF-dependent or -independent mechanisms and reduces the efficacy of docetaxel , 2011, British Journal of Cancer.
[18] A. Moon,et al. Epithelial-mesenchymal Transition and Cell Invasion , 2010, Toxicological research.
[19] L. Zeng,et al. Hyperglycaemia confers resistance to chemotherapy on breast cancer cells: the role of fatty acid synthase. , 2010, Endocrine-related cancer.
[20] M. Pollak,et al. IGFBP‐2 Expression in MCF‐7 Cells is Regulated by the PI3K/AKT/mTOR Pathway through Sp1 Induced Increase in Transcription , 2010, Growth factors.
[21] T. Seyfried,et al. A novel pre-clinical in vivo mouse model for malignant brain tumor growth and invasion , 2010, Journal of Neuro-Oncology.
[22] C. Dinney,et al. Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer , 2009, Cancer and Metastasis Reviews.
[23] G. Fuller,et al. IGFBP2 is a candidate biomarker for Ink4a-Arf status and a therapeutic target for high-grade gliomas , 2009, Proceedings of the National Academy of Sciences.
[24] Ignacio Ramis-Conde,et al. Multi-scale modelling of cancer cell intravasation: the role of cadherins in metastasis , 2009, Physical biology.
[25] R. Sikes,et al. Disease evidence for IGFBP-2 as a key player in prostate cancer progression and development of osteosclerotic lesions. , 2009, American journal of translational research.
[26] Hiroaki Kataoka,et al. Roles of insulin-like growth factor binding protein-2 (IGFBP-2) in glioblastoma. , 2007, Anticancer research.
[27] C. Perks,et al. IGF-II and IGFBP-2 differentially regulate PTEN in human breast cancer cells , 2007, Oncogene.
[28] A. Hoeflich,et al. IGF-independent effects of IGFBP-2 on the human breast cancer cell line Hs578T. , 2006, Journal of molecular endocrinology.
[29] Tetsuhiro Chiba,et al. Identification and investigation of methylated genes in hepatoma. , 2005, European journal of cancer.
[30] M. Gleave,et al. Introduction of insulin-like growth factor binding protein-2 gene into human bladder cancer cells enhances their metastatic potential. , 2005, Oncology reports.
[31] Tanja Woyke,et al. Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets. , 2005, Neoplasia.
[32] N. Ling,et al. Identification of a Nonpeptide Ligand That Releases Bioactive Insulin-like Growth Factor-I from Its Binding Protein Complex* , 2001, The Journal of Biological Chemistry.
[33] E. Wolf,et al. Insulin‐like growth factor‐binding protein‐2 inhibits proliferation of human embryonic kidney fibroblasts and of IGF‐responsive colon carcinoma cell lines , 1998, FEBS letters.