Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice

[1]  C. Hetz,et al.  Protein folding stress in neurodegenerative diseases: a glimpse into the ER. , 2011, Current opinion in cell biology.

[2]  T. Hafmans,et al.  p24 Proteins from the same subfamily are functionally nonredundant. , 2011, Biochimie.

[3]  Pritam Das,et al.  Reduced Alzheimer's Disease β-Amyloid Deposition in Transgenic Mice Expressing S-Palmitoylation-Deficient APH1aL and Nicastrin , 2010, The Journal of Neuroscience.

[4]  S. Wagner,et al.  Mutation Analysis of the Presenilin 1 N-terminal Domain Reveals a Broad Spectrum of γ-Secretase Activity toward Amyloid Precursor Protein and Other Substrates* , 2010, The Journal of Biological Chemistry.

[5]  H. Hauri,et al.  Selective export of human GPI-anchored proteins from the endoplasmic reticulum , 2010, Journal of Cell Science.

[6]  E. Lacy,et al.  The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta. , 2010, Developmental biology.

[7]  Yan Liang,et al.  Induction Profile of MANF/ARMET by Cerebral Ischemia and its Implication for Neuron Protection , 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[8]  M. Sofroniew Molecular dissection of reactive astrogliosis and glial scar formation , 2009, Trends in Neurosciences.

[9]  G. Martens,et al.  The p24 family and selective transport processes at the ER—Golgi interface , 2009, Biology of the cell.

[10]  T. Hafmans,et al.  COP-binding sites in p24delta2 are necessary for proper secretory cargo biosynthesis. , 2009, The international journal of biochemistry & cell biology.

[11]  B. Popko,et al.  Endoplasmic reticulum stress in disorders of myelinating cells , 2009, Nature Neuroscience.

[12]  E. Koo,et al.  Amyloid Precursor Protein Trafficking, Processing, and Function* , 2008, Journal of Biological Chemistry.

[13]  O. Lindvall,et al.  MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain , 2008, Molecular and Cellular Neuroscience.

[14]  S. Kar,et al.  Localization and regional distribution of p23/TMP21 in the brain , 2008, Neurobiology of Disease.

[15]  Y. Maeda,et al.  Mammalian GPI-anchored proteins require p24 proteins for their efficient transport from the ER to the plasma membrane. , 2008, The Biochemical journal.

[16]  Monika Liguz-Lecznar,et al.  Vesicular glutamate transporters (VGLUTs): the three musketeers of glutamatergic system. , 2007, Acta neurobiologiae experimentalis.

[17]  J. Hoseki,et al.  ARMET is a soluble ER protein induced by the unfolded protein response via ERSE-II element. , 2007, Cell structure and function.

[18]  E. Hirsch,et al.  Altered expression of vesicular glutamate transporters VGLUT1 and VGLUT2 in Parkinson disease , 2007, Neurobiology of Aging.

[19]  F. Wieland,et al.  Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism , 2007, Molecular Neurodegeneration.

[20]  W. Streit Microglial senescence: does the brain's immune system have an expiration date? , 2006, Trends in Neurosciences.

[21]  D. Westaway,et al.  TMP21 is a presenilin complex component that modulates γ-secretase but not ɛ-secretase activity , 2006, Nature.

[22]  Juan F Medrano,et al.  Real-time PCR for mRNA quantitation. , 2005, BioTechniques.

[23]  F. Helmchen,et al.  Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo , 2005, Science.

[24]  D. Copenhagen,et al.  Vesicular Glutamate Transporters 1 and 2 Target to Functionally Distinct Synaptic Release Sites , 2004, Science.

[25]  T. Iwatsubo The γ-secretase complex: machinery for intramembrane proteolysis , 2004, Current Opinion in Neurobiology.

[26]  Tsonwin Hai,et al.  Activating Transcription Factor 3 Is Integral to the Eukaryotic Initiation Factor 2 Kinase Stress Response , 2004, Molecular and Cellular Biology.

[27]  F. Wieland,et al.  Oligomeric State and Stoichiometry of p24 Proteins in the Early Secretory Pathway* 210 , 2002, The Journal of Biological Chemistry.

[28]  C. Barlowe,et al.  Deletion of yeast p24 genes activates the unfolded protein response. , 2001, Molecular biology of the cell.

[29]  M. Schapira,et al.  Regulated translation initiation controls stress-induced gene expression in mammalian cells. , 2000, Molecular cell.

[30]  G. Feng,et al.  Imaging Neuronal Subsets in Transgenic Mice Expressing Multiple Spectral Variants of GFP , 2000, Neuron.

[31]  A. McDowall,et al.  The transmembrane protein p23 contributes to the organization of the Golgi apparatus. , 2000, Journal of cell science.

[32]  R. Pepperkok,et al.  The p24 family member p23 is required for early embryonic development , 2000, Current Biology.

[33]  K. A. Clarke,et al.  Gait Analysis in the Mouse , 1999, Physiology & Behavior.

[34]  I. Greenwald,et al.  p24 Proteins and Quality Control of LIN-12 and GLP-1 Trafficking in Caenorhabditis elegans , 1999, The Journal of cell biology.

[35]  M. Marzioch,et al.  Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex. , 1999, Molecular biology of the cell.

[36]  J. Füllekrug,et al.  Localization and recycling of gp27 (hp24gamma3): complex formation with other p24 family members. , 1999, Molecular biology of the cell.

[37]  L. Orci,et al.  p24 and p23, the major transmembrane proteins of COPI‐coated transport vesicles, form hetero‐oligomeric complexes and cycle between the organelles of the early secretory pathway , 1999, FEBS letters.

[38]  W. Nastainczyk,et al.  Intracellular localization and in vivo trafficking of p24A and p23. , 1999, Journal of cell science.

[39]  David Y. Thomas,et al.  gp25L/emp24/p24 Protein Family Members of the cis-Golgi Network Bind Both COP I and II Coatomer , 1998, The Journal of cell biology.

[40]  R. Pepperkok,et al.  Involvement of the Transmembrane Protein p23 in Biosynthetic Protein Transport , 1997, The Journal of cell biology.

[41]  F. Wieland,et al.  p23, a major COPI-vesicle membrane protein, constitutively cycles through the early secretory pathway. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[42]  Pico Caroni,et al.  Overexpression of growth-associated proteins in the neurons of adult transgenic mice , 1997, Journal of Neuroscience Methods.

[43]  G. Kreutzberg Microglia: a sensor for pathological events in the CNS , 1996, Trends in Neurosciences.

[44]  D. Borchelt,et al.  Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo , 1996, Neuron.

[45]  J. Kapfhammer,et al.  Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice , 1995, Cell.

[46]  P. S. St George-Hyslop,et al.  TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. , 2006, Nature.

[47]  T. Iwatsubo The gamma-secretase complex: machinery for intramembrane proteolysis. , 2004, Current opinion in neurobiology.

[48]  T. Wisniewski,et al.  Accumulation of alpha B-crystallin in central nervous system glia and neurons in pathologic conditions. , 1992, The American journal of pathology.