IL-33/ST2 signaling contributes to radicular pain by modulating MAPK and NF-κB activation and inflammatory mediator expression in the spinal cord in rat models of noncompressive lumber disk herniation

[1]  Zhi‐hua Liu,et al.  Resolvin D1 Inhibits Mechanical Hypersensitivity in Sciatica by Modulating the Expression of Nuclear Factor-&kgr;B, Phospho-extracellular Signal–regulated Kinase, and Pro- and Antiinflammatory Cytokines in the Spinal Cord and Dorsal Root Ganglion , 2016, Anesthesiology.

[2]  Peng Tian,et al.  Interleukin-23 may contribute to the pathogenesis of lumbar disc herniation through the IL-23/IL-17 pathway , 2016, Journal of Orthopaedic Surgery and Research.

[3]  B. Ryffel,et al.  Spinal cord oligodendrocyte‐derived alarmin IL‐33 mediates neuropathic pain , 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[4]  P. Han,et al.  Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII–CREB and Astroglial JAK2–STAT3 Cascades in Mice , 2015, Anesthesiology.

[5]  Jian-Gang Luo,et al.  Lipoxin A4 attenuates radicular pain possibly by inhibiting spinal ERK, JNK and NF-κB/p65 and cytokine signals, but not p38, in a rat model of non-compressive lumbar disc herniation , 2015, Neuroscience.

[6]  G. Landreth,et al.  ERK2 Alone Drives Inflammatory Pain But Cooperates with ERK1 in Sensory Neuron Survival , 2015, The Journal of Neuroscience.

[7]  J. Zhao,et al.  Inhibition of Spinal Interlukin-33/ST2 Signaling and Downstream ERK and JNK Pathways in Electroacupuncture Analgesia in Formalin Mice , 2015, PloS one.

[8]  Rachelle Buchbinder,et al.  The global burden of low back pain: estimates from the Global Burden of Disease 2010 study , 2014, Annals of the rheumatic diseases.

[9]  Xiaoyan Lin,et al.  Activation of Spinal NF‐κB/p65 Contributes to Peripheral Inflammation and Hyperalgesia in Rat Adjuvant‐Induced Arthritis , 2013, Arthritis & rheumatology.

[10]  H. Zhang,et al.  Spinal interleukin-33 and its receptor ST2 contribute to bone cancer-induced pain in mice , 2013, Neuroscience.

[11]  J. Alves-Filho,et al.  IL‐33/ST2 signalling contributes to carrageenin‐induced innate inflammation and inflammatory pain: role of cytokines, endothelin‐1 and prostaglandin E2 , 2013, British journal of pharmacology.

[12]  D. Meyerholz,et al.  The Novel Cytokine Interleukin-33 Activates Acinar Cell Proinflammatory Pathways and Induces Acute Pancreatic Inflammation in Mice , 2013, PloS one.

[13]  G. Scuderi,et al.  Cytokine Expression in the Epidural Space: A Model of Noncompressive Disc Herniation-Induced Inflammation , 2013, Spine.

[14]  M. Milovanovic,et al.  IL‐33 attenuates EAE by suppressing IL‐17 and IFN‐γ production and inducing alternatively activated macrophages , 2012, European journal of immunology.

[15]  Jian-Gang Luo,et al.  Small interfering RNA-mediated knockdown of NF-κBp65 attenuates neuropathic pain following peripheral nerve injury in rats. , 2012, European journal of pharmacology.

[16]  S. Jang,et al.  Changes in Expression of mRNA for Interleukin-8 and Effects of Interleukin-8 Receptor Inhibitor in the Spinal Dorsal Horn in a Rat Model of Lumbar Disc Herniation , 2011, Spine.

[17]  Shijie Jin,et al.  Production and functions of IL-33 in the central nervous system , 2011, Brain Research.

[18]  L. Setton,et al.  Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues. , 2010, Arthritis and rheumatism.

[19]  M. Teixeira,et al.  IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy , 2010, Annals of the rheumatic diseases.

[20]  A. Andoh,et al.  Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis , 2010, Journal of Gastroenterology.

[21]  R. Yunes,et al.  The effects of the selective and non‐peptide CXCR2 receptor antagonist SB225002 on acute and long‐lasting models of nociception in mice , 2010, European journal of pain.

[22]  R. Ji,et al.  MAP kinase and pain , 2009, Brain Research Reviews.

[23]  S. Kishida,et al.  Nuclear factor-kappa B decoy suppresses nerve injury and improves mechanical allodynia and thermal hyperalgesia in a rat lumbar disc herniation model , 2009, European Spine Journal.

[24]  F. Liew,et al.  IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice , 2008, Proceedings of the National Academy of Sciences.

[25]  A. Freemont,et al.  Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1β and TNFα expression profile , 2007, Arthritis research & therapy.

[26]  S. Ohtori,et al.  Glial Phosphorylated p38 MAP Kinase Mediates Pain in a Rat Model of Lumbar Disc Herniation and Induces Motor Dysfunction in a Rat Model of Lumbar Spinal Canal Stenosis , 2007, Spine.

[27]  M. Younes,et al.  Prevalence and risk factors of disk-related sciatica in an urban population in Tunisia. , 2006, Joint, bone, spine : revue du rhumatisme.

[28]  L. Sorkin,et al.  Regulation of Peripheral Inflammation by Spinal p38 MAP Kinase in Rats , 2006, PLoS medicine.

[29]  D. Tracey,et al.  Immune and inflammatory mechanisms in neuropathic pain , 2006, Brain Research Reviews.

[30]  I. Decosterd,et al.  A Peptide c-Jun N-Terminal Kinase (JNK) Inhibitor Blocks Mechanical Allodynia after Spinal Nerve Ligation: Respective Roles of JNK Activation in Primary Sensory Neurons and Spinal Astrocytes for Neuropathic Pain Development and Maintenance , 2006, The Journal of Neuroscience.

[31]  J Fernando Bazan,et al.  IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. , 2005, Immunity.

[32]  T. Yamashita,et al.  Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Activation in the Dorsal Root Ganglion (DRG) and Spinal Cord After DRG Injury in Rats , 2005, Spine.

[33]  C. Woolf,et al.  ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model , 2005, Pain.

[34]  N. Boos,et al.  Expression and Distribution of Tumor Necrosis Factor Alpha in Human Lumbar Intervertebral Discs: A Study in Surgical Specimen and Autopsy Controls , 2005, Spine.

[35]  S. Ohtori,et al.  Spinal neural cyclooxygenase-2 mediates pain caused in a rat model of lumbar disk herniation. , 2004, The journal of pain : official journal of the American Pain Society.

[36]  E. Carstens,et al.  Role of TNF-alpha in sensitization of nociceptive dorsal horn neurons induced by application of nucleus pulposus to L5 dorsal root ganglion in rats , 2004, Pain.

[37]  K. Ui-Tei,et al.  Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference. , 2004, Nucleic acids research.

[38]  C. R. Tonussi,et al.  A spinal mechanism for the peripheral anti-inflammatory action of indomethacin , 2003, Brain Research.

[39]  M. Kurosaka,et al.  The Role of Cyclooxygenase-2 in Lumbar Disc Herniation , 2002, Spine.

[40]  Jong-Beom Park,et al.  The Pattern of Interleukin-12 and T-Helper Types 1 and 2 Cytokine Expression in Herniated Lumbar Disc Tissue , 2002, Spine.

[41]  S. Brull,et al.  Increased sensitivity of sensory neurons to tumor necrosis factor alpha in rats with chronic compression of the lumbar ganglia. , 2002, Journal of neurophysiology.

[42]  S. Brull,et al.  Acute topical application of tumor necrosis factor alpha evokes protein kinase A-dependent responses in rat sensory neurons. , 2002, Journal of neurophysiology.

[43]  J. Fitzpatrick,et al.  Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators. , 2002, The Journal of bone and joint surgery. British volume.

[44]  S. Konno,et al.  Epidural Application of Nucleus Pulposus Enhances Nociresponses of Rat Dorsal Horn Neurons , 2002, Spine.

[45]  J. Weinstein,et al.  The Role of Mechanical Deformation in Lumbar Radiculopathy: An In Vivo Model , 2002, Spine.

[46]  M. Kawakami,et al.  mRNA expression of interleukins, phospholipase A2, and nitric oxide synthase in the nerve root and dorsal root ganglion induced by autologous nucleus pulposus in the rat , 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[47]  E. Carstens,et al.  Behavioral manifestations of neuropathic pain and mechanical allodynia, and changes in spinal dorsal horn neurons, following L4–L6 dorsal root constriction in rats , 1999, Pain.

[48]  K. Olmarker,et al.  A Model for Acute, Chronic, and Delayed Graded Compression of the Dog Cauda Equina: Presentation of the Gross, Microscopic, and Vascular Anatomy of the Dog Cauda Equina and Accuracy in Pressure Transmission of the Compression Model , 1995, Spine.

[49]  T. Yaksh,et al.  Quantitative assessment of tactile allodynia in the rat paw , 1994, Journal of Neuroscience Methods.

[50]  M. Zimmermann,et al.  Ethical guidelines for investigations of experimental pain in conscious animals , 1983, Pain.

[51]  T. Yaksh,et al.  Chronic catheterization of the spinal subarachnoid space , 1976, Physiology & Behavior.

[52]  M. Barbosa,et al.  Inflammation in intervertebral disc degeneration and regeneration , 2015, Journal of The Royal Society Interface.

[53]  Robert H Miller,et al.  Isolation and culture of spinal cord astrocytes. , 2012, Methods in molecular biology.

[54]  Ping Han 韩萍,et al.  Research progress on interleukin-33 and its roles in the central nervous system , 2011, Neuroscience Bulletin.