Multilevel Metabolic Engineering of Bacillus amyloliquefaciens for Production of the Platform Chemical Putrescine from Sustainable Biomass Hydrolysates

Putrescine is an important C4 platform chemical with extensive applications in bioplastics, pharmaceuticals, and agrochemicals. In this study, multilevel metabolic engineering of Bacillus amyloliqu...

[1]  Tong Un Chae,et al.  Metabolic engineering for the production of dicarboxylic acids and diamines. , 2020, Metabolic engineering.

[2]  B. Ye,et al.  Metabolic engineering of Corynebacterium glutamicum S9114 to enhance the production of l-ornithine driven by glucose and xylose. , 2019, Bioresource technology.

[3]  Guocheng Du,et al.  Synthetic redesign of central carbon and redox metabolism for high yield production of N-acetylglucosamine in Bacillus subtilis. , 2019, Metabolic engineering.

[4]  Jae Sung Cho,et al.  A comprehensive metabolic map for production of bio-based chemicals , 2019, Nature Catalysis.

[5]  J. Bao,et al.  A preliminary study on l-lysine fermentation from lignocellulose feedstock and techno-economic evaluation. , 2019, Bioresource technology.

[6]  Z. Wen,et al.  Enhanced production of poly‐γ‐glutamic acid by improving ATP supply in metabolically engineered Bacillus licheniformis , 2018, Biotechnology and bioengineering.

[7]  Z. Wen,et al.  Evaluation of the Biogenic Amines Formation and Degradation Abilities of Lactobacillus curvatus From Chinese Bacon , 2018, Front. Microbiol..

[8]  Z. Rao,et al.  Improved l-ornithine production in Corynebacterium crenatum by introducing an artificial linear transacetylation pathway , 2018, Journal of Industrial Microbiology & Biotechnology.

[9]  Shouwen Chen,et al.  Production of optically pure 2,3-butanediol from Miscanthus floridulus hydrolysate using engineered Bacillus licheniformis strains , 2018, World journal of microbiology & biotechnology.

[10]  Weiguo Zhang,et al.  NADPH metabolism: a survey of its theoretical characteristics and manipulation strategies in amino acid biosynthesis , 2018, Critical reviews in biotechnology.

[11]  Bang-Ce Ye,et al.  Enhanced l-ornithine production by systematic manipulation of l-ornithine metabolism in engineered Corynebacterium glutamicum S9114. , 2018, Bioresource technology.

[12]  Guido Kroemer,et al.  Spermidine in health and disease , 2018, Science.

[13]  Yu-Ping Shen,et al.  Metabolic evolution and a comparative omics analysis of Corynebacterium glutamicum for putrescine production , 2018, Journal of Industrial Microbiology & Biotechnology.

[14]  T. Tan,et al.  Cofactor engineering for more efficient production of chemicals and biofuels. , 2017, Biotechnology advances.

[15]  Sang Yup Lee,et al.  Gene Expression Knockdown by Modulating Synthetic Small RNA Expression in Escherichia coli. , 2017, Cell systems.

[16]  Jian-Zhong Liu,et al.  Transcriptomic Changes in Response to Putrescine Production in Metabolically Engineered Corynebacterium glutamicum , 2017, Front. Microbiol..

[17]  Yixue Li,et al.  Systematic pathway engineering of Corynebacterium glutamicum S9114 for l-ornithine production , 2017, Microbial Cell Factories.

[18]  Z. Wen,et al.  Enhancement of acetoin production from Bacillus licheniformis by 2,3-butanediol conversion strategy: Metabolic engineering and fermentation control , 2017 .

[19]  Z. Wen,et al.  A novel approach to improve poly-γ-glutamic acid production by NADPH Regeneration in Bacillus licheniformis WX-02 , 2017, Scientific Reports.

[20]  Z. Rao,et al.  Improvement of the intracellular environment for enhancing l-arginine production of Corynebacterium glutamicum by inactivation of H2O2-forming flavin reductases and optimization of ATP supply. , 2016, Metabolic engineering.

[21]  Zhiyou Wen,et al.  Engineering Bacillus licheniformis for the production of meso-2,3-butanediol , 2016, Biotechnology for Biofuels.

[22]  Ming Yan,et al.  Implication of ornithine acetyltransferase activity on l‐ornithine production in Corynebacterium glutamicum , 2016, Biotechnology and applied biochemistry.

[23]  Chao Yang,et al.  Improved poly-γ-glutamic acid production in Bacillus amyloliquefaciens by modular pathway engineering. , 2015, Metabolic engineering.

[24]  B. Jiang,et al.  Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine , 2015, Nature Communications.

[25]  Chao Yang,et al.  Recruiting a new strategy to improve levan production in Bacillus amyloliquefaciens , 2015, Scientific Reports.

[26]  J. van der Oost,et al.  NADPH-generating systems in bacteria and archaea , 2015, Front. Microbiol..

[27]  Wen‐Chien Lee,et al.  Miscanthus as cellulosic biomass for bioethanol production , 2015, Biotechnology journal.

[28]  Jens Schneider,et al.  Elimination of polyamine N-acetylation and regulatory engineering improved putrescine production by Corynebacterium glutamicum. , 2015, Journal of biotechnology.

[29]  V. Wendisch,et al.  Fermentative Production of the Diamine Putrescine: System Metabolic Engineering of Corynebacterium Glutamicum , 2015, Metabolites.

[30]  Sang Yup Lee,et al.  Metabolic engineering of Corynebacterium glutamicum for the production of L-ornithine. , 2015, Biotechnology and bioengineering.

[31]  Dan Wang,et al.  Efficient expression of nattokinase in Bacillus licheniformis: host strain construction and signal peptide optimization , 2015, Journal of Industrial Microbiology & Biotechnology.

[32]  Jung Min Choi,et al.  Rational design of ornithine decarboxylase with high catalytic activity for the production of putrescine , 2014, Applied Microbiology and Biotechnology.

[33]  S. Lee,et al.  Metabolic engineering of Corynebacterium glutamicum for L-arginine production , 2011, Nature Communications.

[34]  Volker F Wendisch,et al.  Crude glycerol-based production of amino acids and putrescine by Corynebacterium glutamicum. , 2013, Bioresource technology.

[35]  Jian-Zhong Liu,et al.  Metabolic engineering of Corynebacterium glutamicum for increasing the production of l-ornithine by increasing NADPH availability , 2013, Journal of Industrial Microbiology & Biotechnology.

[36]  Xueli Zhang,et al.  Engineering central metabolic modules of Escherichia coli for improving β-carotene production. , 2013, Metabolic engineering.

[37]  C. Collins,et al.  Modular optimization of multi-gene pathways for fatty acids production in E. coli , 2013, Nature Communications.

[38]  K Madhavan Nampoothiri,et al.  Accelerated pentose utilization by Corynebacterium glutamicum for accelerated production of lysine, glutamate, ornithine and putrescine , 2012, Microbial biotechnology.

[39]  Christoph Wittmann,et al.  Systems and synthetic metabolic engineering for amino acid production - the heartbeat of industrial strain development. , 2012, Current opinion in biotechnology.

[40]  V. Wendisch,et al.  Improving putrescine production by Corynebacterium glutamicum by fine-tuning ornithine transcarbamoylase activity using a plasmid addiction system , 2012, Applied Microbiology and Biotechnology.

[41]  Jeong Wook Lee,et al.  Microbial production of building block chemicals and polymers. , 2011, Current opinion in biotechnology.

[42]  Lars M Blank,et al.  Grand challenge commentary: Chassis cells for industrial biochemical production. , 2010, Nature chemical biology.

[43]  V. Wendisch,et al.  Putrescine production by engineered Corynebacterium glutamicum , 2010, Applied Microbiology and Biotechnology.

[44]  G. Hwang,et al.  Identification of a suppressor gene for the arginine-auxotrophic argJ mutation in Corynebacterium glutamicum , 2010, Journal of Industrial Microbiology & Biotechnology.

[45]  S. Lee,et al.  Metabolic engineering of Escherichia coli for the production of putrescine: a four carbon diamine. , 2009, Biotechnology and bioengineering.

[46]  Hans Mooibroek,et al.  Bio-refinery as the bio-inspired process to bulk chemicals. , 2007, Macromolecular bioscience.

[47]  S Baumberg,et al.  Operator interactions by the Bacillus subtilis arginine repressor/activator, AhrC: novel positioning and DNA‐mediated assembly of a transcriptional activator at catabolic sites , 1997, Molecular microbiology.

[48]  S Baumberg,et al.  Purification and initial characterization of AhrC: the regulator of arginine metabolism genes in Bacillus subtilis , 1992, Molecular microbiology.