Synthesis and investigation of anti-inflammatory activity of novel nitric oxide donating hybrid drugs

[1]  F. Awadallah,et al.  Synthesis, anti-inflammatory and ulcerogenicity studies of some substituted pyrimido[1,6-a]azepine derivatives. , 2010, European journal of medicinal chemistry.

[2]  W. Hörl.  Nonsteroidal Anti-Inflammatory Drugs and the Kidney , 2010, Pharmaceuticals.

[3]  K. Shah,et al.  Synthesis and antiinflammatory activity of n-aryl anthranilic acid and its derivatives , 2007 .

[4]  L. Keefer,et al.  O2-acetoxymethyl-protected diazeniumdiolate-based NSAIDs (NONO-NSAIDs): synthesis, nitric oxide release, and biological evaluation studies. , 2007, Bioorganic & medicinal chemistry.

[5]  J. Brophy,et al.  Association of selective and conventional nonsteroidal antiinflammatory drugs with acute renal failure: A population-based, nested case-control analysis. , 2006, American journal of epidemiology.

[6]  G. Mounier,et al.  Atteintes rénales graves au cours d’un traitement par anti-inflammatoires non stéroïdiens arylcarboxyliques : bilan d’une enquête nationale de pharmacovigilance , 2006 .

[7]  I. Bjarnason,et al.  Is non-steroidal anti-inflammaory drug (NSAID) enteropathy clinically more important than NSAID gastropathy? , 2006, Postgraduate Medical Journal.

[8]  A. Abadi,et al.  Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory agents. , 2005, Bioorganic & medicinal chemistry.

[9]  B. Cryer.  NSAID-Associated Deaths: The Rise and Fall of NSAID-Associated GI Mortality , 2005, The American Journal of Gastroenterology.

[10]  D. Praticò,et al.  Adverse cardiovascular effects of the coxibs. , 2005, Journal of medicinal chemistry.

[11]  S. Doggrell.  The safety of lumiracoxib when used in the treatment of arthritis , 2005, Expert opinion on pharmacotherapy.

[12]  M. Lazzaroni,et al.  Gastrointestinal side‐effects of traditional non‐steroidal anti‐inflammatory drugs and new formulations , 2004, Alimentary pharmacology & therapeutics.

[13]  C. Hawkey,et al.  Assessment of non-steroidal anti-inflammatory drug (NSAID) damage in the human gastrointestinal tract. , 2003, British journal of clinical pharmacology.

[14]  J. Wallace,et al.  The therapeutic potential of NO‐NSAIDs , 2003, Fundamental & clinical pharmacology.

[15]  J. Wallace,et al.  Nitric oxide in mucosal defense: a little goes a long way. , 2000, Gastroenterology.

[16]  J. Wallace,et al.  Enhanced anti-inflammatory effects of a nitric oxide-releasing derivative of mesalamine in rats. , 1999, Gastroenterology.

[17]  G. Triadafilopoulos,et al.  Epidemiology of NSAID induced gastrointestinal complications. , 1999, The Journal of rheumatology. Supplement.

[18]  K. Takeuchi,et al.  Role of Nitric Oxide in Pathogenesis of Aspirin-Induced Gastric Mucosal Damage in Rats , 1998, Digestion.

[19]  L. Fändriks,et al.  Acid-induced duodenal mucosal nitric oxide output parallels bicarbonate secretion in the anaesthetized pig. , 1998, Acta physiologica Scandinavica.

[20]  R. Zatz,et al.  Nitroflurbiprofen, a new nonsteroidal anti-inflammatory, ameliorates structural injury in the remnant kidney. , 1998, American journal of physiology. Renal physiology.

[21]  J. Wallace,et al.  A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats. , 1995, Gastroenterology.

[22]  J. F. Brown,et al.  Nitric oxide generators and cGMP stimulate mucus secretion by rat gastric mucosal cells. , 1993, The American journal of physiology.

[23]  C A WINTER,et al.  Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs , 1962, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[24]  P. Murumkar,et al.  Prodrug designing of NSAIDs. , 2009, Mini reviews in medicinal chemistry.

[25]  R. Botting.  Cyclooxygenase: Past, present and future. A tribute to John R. Vane (1927–2004) , 2006 .

[26]  M. Beyens,et al.  [Severe renal adverse events with arylcarboxylic non-steroidal anti-inflammatory drugs: results of a eight-year French national survey]. , 2006, Therapie.

[27]  K. Brown,et al.  NSAID-Associated Adverse Effects and Acid Control Aids to Prevent Them , 2006, Drug safety.

[28]  A. Vogel,et al.  Vogel's Textbook of Practical Organic Chemistry , 2003 .

[29]  R. Hunt,et al.  Recommendations for the appropriate use of anti-inflammatory drugs in the era of the coxibs: defining the role of gastroprotective agents. , 2002, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

[30]  J. Wallace.  Gastric ulceration: critical events at the neutrophil--endothelium interface. , 1993, Canadian journal of physiology and pharmacology.

[31]  R. Koster,et al.  ACETIC ACID FOR ANALGESIC SCREENING , 1959 .