Systemic nature of endothelial dysfunction in atherosclerosis.

[1]  L. Ignarro,et al.  Endothelium‐Derived Relaxing Factor From Pulmonary Artery and Vein Possesses Pharmacologic and Chemical Properties Identical to Those of Nitric Oxide Radical , 1987, Circulation research.

[2]  M. Nakamura,et al.  Endothelium determines flow-dependent dilation of the epicardial coronary artery in dogs. , 1988, Journal of the American College of Cardiology.

[3]  Craig D. Miller,et al.  Management of Patients With Intramural Hematoma of the Thoracic Aorta , 1993, Circulation.

[4]  A. Yeung,et al.  The effect of atherosclerosis on the vasomotor response of coronary arteries to mental stress. , 1991, The New England journal of medicine.

[5]  H. Drexler,et al.  Endothelial Dysfunction of the Coronary Microvasculature Is Associated With Impaired Coronary Blood Flow Regulation in Patients With Early Atherosclerosis , 1991, Circulation.

[6]  K. Fox,et al.  Hemoglobin Inhibits Endothelium‐Dependent Relaxation to Acetlcholine in Human Coronary Arteries In Vivo , 1993, Circulation.

[7]  E. Nabel,et al.  Large coronary arteries in humans are responsive to changing blood flow: an endothelium-dependent mechanism that fails in patients with atherosclerosis. , 1990, Journal of the American College of Cardiology.

[8]  H. Drexler,et al.  Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis. , 1991, Circulation.

[9]  M. Condorelli,et al.  Divergent effects of serotonin on coronary-artery dimensions and blood flow in patients with coronary atherosclerosis and control patients. , 1991, The New England journal of medicine.

[10]  J. Hodgson,et al.  Direct vasoconstriction and endothelium-dependent vasodilation. Mechanisms of acetylcholine effects on coronary flow and arterial diameter in patients with nonstenotic coronary arteries. , 1989, Circulation.

[11]  M. Sugimachi,et al.  Impaired coronary blood flow response to acetylcholine in patients with coronary risk factors and proximal atherosclerotic lesions. , 1993, The Journal of clinical investigation.

[12]  R Busse,et al.  Crucial role of endothelium in the vasodilator response to increased flow in vivo. , 1986, Hypertension.

[13]  J. Hodgson,et al.  Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factors for atherosclerosis. , 1994, Journal of the American College of Cardiology.

[14]  E. Nabel,et al.  Atherosclerosis influences the vasomotor response of epicardial coronary arteries to exercise. , 1989, The Journal of clinical investigation.

[15]  R. Furchgott,et al.  The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine , 1980, Nature.

[16]  P. Ganz,et al.  Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. , 1986, The New England journal of medicine.

[17]  T Sandor,et al.  Differential impairment of vasodilator responsiveness of peripheral resistance and conduit vessels in humans with atherosclerosis. , 1991, Circulation research.

[18]  S. Moncada,et al.  The L-arginine-nitric oxide pathway. , 1993, The New England journal of medicine.

[19]  J. K. Lloyd,et al.  Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis , 1992, The Lancet.

[20]  A. Yeung,et al.  Role of impaired endothelium-dependent vasodilation in ischemic manifestations of coronary artery disease , 1993 .

[21]  G. Rubanyi.  Cardiovascular significance of endothelium-derived vasoactive factors , 1992 .

[22]  D. Celermajer,et al.  Cigarette Smoking Is Associated With Dose‐Related and Potentially Reversible Impairment of Endothelium‐Dependent Dilation in Healthy Young Adults , 1993, Circulation.

[23]  A. Maseri,et al.  Effect of Inhibition of Nitric Oxide Synthesis on Epicardial Coronary Artery Caliber and Coronary Blood Flow in Humans , 1993, Circulation.

[24]  G. Schuler,et al.  Regular Physical Exercise and Low‐Fat Diet: Effects on Progression of Coronary Artery Disease , 1992, Circulation.

[25]  A. Yeung,et al.  Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease. , 1990, Circulation.

[26]  S. Moncada,et al.  Vascular endothelial cells synthesize nitric oxide from L-arginine , 1988, Nature.

[27]  J. Loscalzo,et al.  Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans. , 1990, The Journal of clinical investigation.

[28]  M. Creager,et al.  Impaired Endothelium‐Dependent Vasodilation in Patients With Insulin‐Dependent Diabetes Mellitus , 1993, Circulation.