Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA.
暂无分享,去创建一个
Trey Ideker | Kang Zhang | Daniel Chen | Jason F Kreisberg | Ken Flagg | Hui Shen | Mahdieh Khosroheidari | Susan Swindells | Andrew M. Gross | T. Ideker | Kang Zhang | Hui Shen | Katherine Licon | S. Swindells | J. Kreisberg | C. Ng | K. Jepsen | H. Fox | Ken Flagg | Daniel Chen | Philipp A. Jaeger | B. Morsey | Howard S Fox | Andrew M Gross | Katherine Licon | M. Khosroheidari | Philipp A Jaeger | Kristen L Jepsen | Brenda M Morsey | Cherie T Ng | Kristen Jepsen | Mahdieh Khosroheidari
[1] E. Barker,et al. Killing of human immunodeficiency virus-infected primary T-cell blasts by autologous natural killer cells is dependent on the ability of the virus to alter the expression of major histocompatibility complex class I molecules. , 2004, Blood.
[2] M. Budoff,et al. HIV infection and the risk of acute myocardial infarction. , 2013, JAMA internal medicine.
[3] S. Horvath,et al. DNA methylation age of blood predicts all-cause mortality in later life , 2015, Genome Biology.
[4] B. Thiers,et al. CD4+ Count–Guided Interruption of Antiretroviral Treatment , 2007 .
[5] Richard M Myers,et al. Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape , 2013, Genome Biology.
[6] S. Lewin,et al. No Difference in the Rate of Change in Telomere Length or Telomerase Activity in HIV-Infected Patients after Three Years of Darunavir/Ritonavir with and without Nucleoside Analogues in the MONET Trial , 2014, PloS one.
[7] S. Horvath,et al. Acceleration of Age-Associated Methylation Patterns in HIV-1-Infected Adults , 2015, PloS one.
[8] Michael J. Taylor,et al. HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy , 2010, Neurology.
[9] B. Gazzard,et al. Increasing burden of liver disease in patients with HIV infection , 2011, The Lancet.
[10] D. Douek,et al. Systemic effects of inflammation on health during chronic HIV infection. , 2013, Immunity.
[11] D. Absher,et al. Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell Populations , 2013, PLoS genetics.
[12] A. Bird,et al. CpG islands and the regulation of transcription. , 2011, Genes & development.
[13] R. Hogg,et al. Predictors of CD4:CD8 Ratio Normalization and Its Effect on Health Outcomes in the Era of Combination Antiretroviral Therapy , 2013, PloS one.
[14] David Heckerman,et al. Influence of HLA-C Expression Level on HIV Control , 2013 .
[15] Andrew E. Teschendorff,et al. An integrative network algorithm identifies age-associated differential methylation interactome hotspots targeting stem-cell differentiation pathways , 2013, Scientific Reports.
[16] N E Day,et al. European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection , 2002, Public Health Nutrition.
[17] H. Cooke,et al. In vivo loss of telomeric repeats with age in humans. , 1991, Mutation research.
[18] S. Rowland-Jones,et al. Premature ageing of the immune system: the cause of AIDS? , 2002, Trends in immunology.
[19] S. Gange,et al. Comparison of risk and age at diagnosis of myocardial infarction, end-stage renal disease, and non-AIDS-defining cancer in HIV-infected versus uninfected adults. , 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[20] Jack T Stapleton,et al. The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation , 2010, Science.
[21] A. Roverato,et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[22] S. Lewin,et al. Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging. , 2013, The Journal of infectious diseases.
[23] E. Schadt,et al. Geroscience: Linking Aging to Chronic Disease , 2014, Cell.
[24] P. Krogstad,et al. Immunological response to highly active antiretroviral therapy in children with clinically stable HIV-1 infection. , 2005, The Journal of infectious diseases.
[25] Jacques Fellay,et al. A Whole-Genome Association Study of Major Determinants for Host Control of HIV-1 , 2007, Science.
[26] Wolfgang Wagner,et al. Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. , 2010, Genome research.
[27] J Darbyshire,et al. CD4+ count-guided interruption of antiretroviral treatment. , 2006, The New England journal of medicine.
[28] J. Singer,et al. Association between short leukocyte telomere length and HIV infection in a cohort study: No evidence of a relationship with antiretroviral therapy. , 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[29] R. Weber,et al. Antiretroviral drug-related liver mortality among HIV-positive persons in the absence of hepatitis B or C virus coinfection: the data collection on adverse events of anti-HIV drugs study. , 2013, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[30] S. Horvath,et al. HIV-1 Infection Accelerates Age According to the Epigenetic Clock , 2015, The Journal of infectious diseases.
[31] Connie Celum,et al. HIV infection: epidemiology, pathogenesis, treatment, and prevention , 2014, The Lancet.
[32] Ina Hoeschele,et al. Age-related variations in the methylome associated with gene expression in human monocytes and T cells , 2014, Nature Communications.
[33] J. Kleinman,et al. DNA methylation signatures in development and aging of the human prefrontal cortex. , 2012, American journal of human genetics.
[34] R. Irizarry,et al. Accounting for cellular heterogeneity is critical in epigenome-wide association studies , 2014, Genome Biology.
[35] J. Tegnér,et al. An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform , 2013, Epigenetics.
[36] Rafael A. Irizarry,et al. Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays , 2014, Bioinform..
[37] Rakhee Banerjee,et al. Polycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistance , 2009, Proceedings of the National Academy of Sciences.
[38] F. Pereyra,et al. Differential microRNA regulation of HLA-C expression and its association with HIV control , 2011, Nature.
[39] Zachary D. Smith,et al. Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging. , 2013, Cell stem cell.
[40] Donald Eugene. Farrar,et al. Multicollinearity in Regression Analysis; the Problem Revisited , 2011 .
[41] S. Lee,et al. Combination nucleoside analog reverse transcriptase inhibitor(s) plus nevirapine, nelfinavir, or ritonavir in stable antiretroviral therapy-experienced HIV-infected children: week 24 results of a randomized controlled trial--PACTG 377. Pediatric AIDS Clinical Trials Group 377 Study Team. , 2000, AIDS research and human retroviruses.
[42] Catherine A. Sugar,et al. The Dual Impact of HIV-1 Infection and Aging on Naïve CD4+ T-Cells: Additive and Distinct Patterns of Impairment , 2011, PloS one.
[43] B. Walker,et al. HIV and HLA class I: an evolving relationship. , 2012, Immunity.
[44] R. Detels,et al. Premature Aging of T cells Is Associated With Faster HIV-1 Disease Progression , 2009, Journal of acquired immune deficiency syndromes.
[45] Alfonso Valencia,et al. Distinct DNA methylomes of newborns and centenarians , 2012, Proceedings of the National Academy of Sciences.
[46] S. Horvath,et al. Longitudinal changes of telomere length and epigenetic age related to traumatic stress and post-traumatic stress disorder , 2015, Psychoneuroendocrinology.
[47] M. Lederman,et al. HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality , 2014, PLoS pathogens.
[48] E. Soliman,et al. Determinants of developing widened spatial QRS-T angle in HIV-infected individuals: results from the Strategies for Management of Antiretroviral Therapy [SMART] Study. , 2014, Journal of electrocardiology.
[49] Francesco Marabita,et al. A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data , 2012, Bioinform..
[50] Steve Horvath,et al. Accelerated epigenetic aging in Down syndrome , 2015, Aging cell.
[51] Richard D Moore,et al. Long-Term CD4+ Cell Count in Response to Combination Antiretroviral Therapy , 2014, PloS one.
[52] S. Lawn,et al. Accelerated biological ageing in HIV-infected individuals in South Africa: a case–control study , 2013, AIDS.
[53] R. Choudhury,et al. HIV Infection , Inflammation , Immunosenescence , and Aging , 2011 .
[54] Devin C. Koestler,et al. DNA methylation arrays as surrogate measures of cell mixture distribution , 2012, BMC Bioinformatics.
[55] S. Horvath. DNA methylation age of human tissues and cell types , 2013, Genome Biology.
[56] C. Van Lint,et al. HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals , 2010, Science.
[57] S. Brul,et al. Premature and accelerated aging: HIV or HAART? , 2013, Front. Gene..
[58] D. Ge,et al. HLA-C cell surface expression and control of HIV / AIDS correlate with a variant upstream of HLA-C , 2009 .
[59] D. Baltimore,et al. The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells. , 1999, Immunity.
[60] Raimund Erbel,et al. Aging of blood can be tracked by DNA methylation changes at just three CpG sites , 2014, Genome Biology.
[61] B. Christensen,et al. Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context , 2009, PLoS genetics.
[62] A. Winston,et al. Controversies in HIV-associated neurocognitive disorders , 2014, The Lancet Neurology.
[63] William Lewis,et al. Aging and HIV/AIDS: pathogenetic role of therapeutic side effects , 2014, Laboratory Investigation.
[64] Ingrid K. Glad,et al. Estimated Comparative Integration Hotspots Identify Different Behaviors of Retroviral Gene Transfer Vectors , 2011, PLoS Comput. Biol..
[65] T. Ideker,et al. Genome-wide methylation profiles reveal quantitative views of human aging rates. , 2013, Molecular cell.
[66] R. Cawthon,et al. Association between telomere length in blood and mortality in people aged 60 years or older , 2003, The Lancet.
[67] A. Justice,et al. HIV infection, aging, and immune function: implications for cancer risk and prevention , 2012, Current opinion in oncology.