A case of pulmonary sclerosing hemangioma with low (18)FDG uptake in PET.

Pulmonary sclerosing hemangioma (PSH) is a relatively rare benign neoplasm, often asymptomatic and presenting as a solitary pulmonary nodule on radiological imaging studies. In the present case report, we examined a case of PSH in a young adult female, and reviewed the literature pertaining to PSH with an emphasis on (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)FDG PET/CT) and pathology. Immunohistochemical staining was also performed to confirm the diagnosis of sclerosing hemangioma. The results revealed that the tumor cells were immunopositive for epithelial membrane antigen, thyroid transcription factor-1 and vimentin and cytoskeleton 7. The patient recovered and was discharged. Thus, (18)FDG PET/CT may be used in the diagnosis of a solitary benign pulmonary nodule.

[1]  Yu-Chung Wu,et al.  Pulmonary sclerosing haemangioma mimicking lung cancer on PET scan , 2009, Respirology.

[2]  W. Oyen,et al.  Pulmonary Sclerosing Hemangioma Detected by Fluorodeoxyglucose Positron Emission Tomography in Familial Adenomatous Polyposis: Report of a Case , 2007, Diseases of the colon and rectum.

[3]  T. Fukuse,et al.  Pulmonary sclerosing hemangioma with pulmonary metastasis. , 2006, The Thoracic and cardiovascular surgeon.

[4]  Y. Haga,et al.  Clinicopathological analysis of pulmonary sclerosing hemangioma. , 2004, The Annals of thoracic surgery.

[5]  R. Deshpande,et al.  Multiple Sclerosing Hemangiomas of the Lung , 2004, Asian cardiovascular & thoracic annals.

[6]  D. Lin,et al.  Immunohistochemical and ultrastructural markers suggest different origins for cuboidal and polygonal cells in pulmonary sclerosing hemangioma. , 2004, Human pathology.

[7]  T. Colby,et al.  Pulmonary sclerosing hemangioma with lymph node metastases: report of 4 cases. , 2003, Archives of pathology & laboratory medicine.

[8]  M. Hara,et al.  FDG-PET findings in sclerosing hemangioma of the lung: a case report. , 2001, Radiation medicine.

[9]  W. Travis,et al.  A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies: TTF-1 is expressed in both round and surface cells, suggesting an origin from primitive respiratory epithelium. , 2000, The American journal of surgical pathology.

[10]  M. Nakajo,et al.  Sclerosing hemangioma of the lung: MR findings and correlation with pathological features. , 1998, Journal of computer assisted tomography.

[11]  J. Im,et al.  Sclerosing Hemangiomas of the Lung and Interlobar Fissures: CT Findings , 1994, Journal of computer assisted tomography.

[12]  K. Sugimachi,et al.  Sclerosing hemangioma of the lung: radiographic and pathological study. , 1992, The Annals of thoracic surgery.

[13]  A. Liebow,et al.  Sclerosing hemangioma (histiocytoma, xanthoma) of the lung , 1956, Cancer.