Prion protein conversion in vitro

[1]  B. Caughey,et al.  A solid-phase assay for identification of modulators of prion protein interactions. , 2003, Analytical biochemistry.

[2]  S. Supattapone,et al.  RNA molecules stimulate prion protein conversion , 2003, Nature.

[3]  J. Esko,et al.  Cellular Heparan Sulfate Participates in the Metabolism of Prions* , 2003, Journal of Biological Chemistry.

[4]  L. Stoltze,et al.  A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[5]  R. Rubenstein,et al.  Small, highly structured RNAs participate in the conversion of human recombinant PrP(Sen) to PrP(Res) in vitro. , 2003, Journal of molecular biology.

[6]  G. J. Raymond,et al.  Inhibition of Protease-Resistant Prion Protein Accumulation In Vitro by Curcumin , 2003, Journal of Virology.

[7]  S. Supattapone,et al.  In vitro amplification of protease-resistant prion protein requires free sulfhydryl groups. , 2003, Biochemistry.

[8]  V. Kryukov,et al.  Concentration and removal of prion proteins from biological solutions , 2003, Biotechnology and applied biochemistry.

[9]  Yaping Gu,et al.  Identification of cryptic nuclear localization signals in the prion protein , 2003, Neurobiology of Disease.

[10]  E. Cohen,et al.  Scrapie‐like prion protein accumulates in aggresomes of cyclosporin A‐treated cells , 2003, The EMBO journal.

[11]  S. Lindquist,et al.  Conversion of PrP to a Self-Perpetuating PrPSc-like Conformation in the Cytosol , 2002, Science.

[12]  P. Nandi,et al.  DNA-induced partial unfolding of prion protein leads to its polymerisation to amyloid. , 2002, Journal of molecular biology.

[13]  H. Scheraga,et al.  Intramolecular Versus Intermolecular Disulfide Bonds in Prion Proteins* , 2002, The Journal of Biological Chemistry.

[14]  M. Famulok,et al.  Prion‐Protein‐Specific Aptamer Reduces PrPSc Formation , 2002, Chembiochem : a European journal of chemical biology.

[15]  J. Wissler Engineering of Capillary Patterns in Muscle by a Nonmitogenic Copper‐Ribonucleoprotein Angiomorphogen [Angiotropin CuRNP Ribokine] , 2002, Annals of the New York Academy of Sciences.

[16]  J. Turnbull,et al.  Identification of the Heparan Sulfate Binding Sites in the Cellular Prion Protein* , 2002, The Journal of Biological Chemistry.

[17]  S. L. Le Grice,et al.  Functional interactions of nucleocapsid protein of feline immunodeficiency virus and cellular prion protein with the viral RNA. , 2002, Journal of molecular biology.

[18]  István Simon,et al.  The role of dimerization in prion replication. , 2002, Biophysical journal.

[19]  B. Chesebro,et al.  Conversion of raft associated prion protein to the protease‐resistant state requires insertion of PrP‐res (PrPSc) into contiguous membranes , 2002, The EMBO journal.

[20]  Craig P. Hunter,et al.  Systemic RNAi in C. elegans Requires the Putative Transmembrane Protein SID-1 , 2002, Science.

[21]  C. Gabus,et al.  PrPC has nucleic acid chaperoning properties similar to the nucleocapsid protein of HIV-1. , 2002, Comptes rendus biologies.

[22]  D. Dormont,et al.  Identification of interaction domains of the prion protein with its 37‐kDa/67‐kDa laminin receptor , 2001, The EMBO journal.

[23]  Albert Taraboulos,et al.  Proteasomes and ubiquitin are involved in the turnover of the wild‐type prion protein , 2001, The EMBO journal.

[24]  Y. Shaked,et al.  A Protease-resistant Prion Protein Isoform Is Present in Urine of Animals and Humans Affected with Prion Diseases* , 2001, The Journal of Biological Chemistry.

[25]  F. Hartl,et al.  A sensitive filter retention assay for the detection of PrPSc and the screening of anti‐prion compounds , 2001 .

[26]  B. Permanne,et al.  Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding , 2001, Nature.

[27]  C. Gabus,et al.  The Prion Protein Has RNA Binding and Chaperoning Properties Characteristic of Nucleocapsid Protein NCp7 of HIV-1* , 2001, The Journal of Biological Chemistry.

[28]  Z. Meiner,et al.  Reconstitution of Prion Infectivity from Solubilized Protease-resistant PrP and Nonprotein Components of Prion Rods* , 2001, The Journal of Biological Chemistry.

[29]  C. Péchoux,et al.  The prion protein has DNA strand transfer properties similar to retroviral nucleocapsid protein. , 2001, Journal of molecular biology.

[30]  F. Cohen,et al.  Branched Polyamines Cure Prion-Infected Neuroblastoma Cells , 2001, Journal of Virology.

[31]  H. Scheraga,et al.  A role for intermolecular disulfide bonds in prion diseases? , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[32]  B. Chesebro,et al.  Sulfated glycans and elevated temperature stimulate PrPSc‐dependent cell‐free formation of protease‐resistant prion protein , 2001, The EMBO journal.

[33]  M. Feughelman,et al.  Thiol-disulfide interchange a potential key to conformational change associated with amyloid fibril formation. , 2000, Journal of theoretical biology.

[34]  B. Caughey,et al.  Lysosomotropic Agents and Cysteine Protease Inhibitors Inhibit Scrapie-Associated Prion Protein Accumulation , 2000, Journal of virology.

[35]  W. Caughey,et al.  Porphyrin and phthalocyanine antiscrapie compounds. , 2000, Science.

[36]  B. Chesebro,et al.  Inhibition of formation of protease-resistant prion protein by Trypan Blue, Sirius Red and other Congo Red analogs. , 2000, Archives of virology. Supplementum.

[37]  F. Cohen,et al.  Quantitative traits of prion strains are enciphered in the conformation of the prion protein. , 2000, Archives of virology. Supplementum.

[38]  F. Cohen,et al.  Elimination of prions by branched polyamines and implications for therapeutics. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[39]  J. Collinge,et al.  Strain-specific prion-protein conformation determined by metal ions , 1999, Nature Cell Biology.

[40]  J Collinge,et al.  Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations. , 1999, Science.

[41]  J. Aiken,et al.  Reversibility of Scrapie Inactivation Is Enhanced by Copper* , 1998, The Journal of Biological Chemistry.

[42]  F. Cohen,et al.  Eight prion strains have PrPSc molecules with different conformations , 1998, Nature Medicine.

[43]  B. Caughey,et al.  The importance of the disulfide bond in prion protein conversion , 1998, Neuroreport.

[44]  S. Prusiner,et al.  A transmembrane form of the prion protein in neurodegenerative disease. , 1998, Science.

[45]  M. Famulok,et al.  RNA aptamers specifically interact with the prion protein PrP , 1997, Journal of virology.

[46]  F E Cohen,et al.  A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform. , 1997, Journal of molecular biology.

[47]  P. Lansbury,et al.  Molecular assessment of the potential transmissibilities of BSE and scrapie to humans , 1997, Nature.

[48]  G. J. Raymond,et al.  Scrapie susceptibility-linked polymorphisms modulate the in vitro conversion of sheep prion protein to protease-resistant forms. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[49]  F. Cohen,et al.  Physical studies of conformational plasticity in a recombinant prion protein. , 1997, Biochemistry.

[50]  S. Prusiner,et al.  Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[51]  F. Cohen,et al.  High-level expression and characterization of a purified 142-residue polypeptide of the prion protein. , 1996, Biochemistry.

[52]  S. Prusiner,et al.  Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity , 1996, Journal of virology.

[53]  P. Lansbury,et al.  Non-genetic propagation of strain-specific properties of scrapie prion protein , 1995, Nature.

[54]  P. Lansbury,et al.  Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[55]  R. Marsh,et al.  Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy , 1994, Journal of virology.

[56]  P. Lansbury,et al.  Cell-free formation of protease-resistant prion protein , 1994, Nature.

[57]  R J Fletterick,et al.  Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[58]  P. Roller,et al.  Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein. , 1993, The Journal of biological chemistry.

[59]  S. Prusiner,et al.  Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes , 1993, Cell.

[60]  G. J. Raymond,et al.  Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells , 1993, Journal of virology.

[61]  R. Marsh,et al.  Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent , 1992, Journal of virology.

[62]  R. Marsh,et al.  Identification of two biologically distinct strains of transmissible mink encephalopathy in hamsters. , 1992, The Journal of general virology.

[63]  S. Prusiner,et al.  Prion biology and diseases. , 1999, Harvey lectures.

[64]  B. Caughey,et al.  Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy. , 1991, Biochemistry.

[65]  S. Prusiner,et al.  Three hamster species with different scrapie incubation times and neuropathological features encode distinct prion proteins , 1990, Molecular and cellular biology.

[66]  Stephen J. DeArmond,et al.  Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques , 1989, Cell.

[67]  L. Hood,et al.  Purification and properties of the cellular and scrapie hamster prion proteins. , 1988, European journal of biochemistry.

[68]  Stanley B. Prusiner,et al.  Scrapie prion protein contains a phosphatidylinositol glycolipid , 1987, Cell.

[69]  S. Prusiner,et al.  Purified scrapie prions resist inactivation by procedures that hydrolyze, modify, or shear nucleic acids. , 1987, Virology.

[70]  S. Prusiner,et al.  Purified prion proteins and scrapie infectivity copartition into liposomes. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[71]  S. Prusiner,et al.  Separation and properties of cellular and scrapie prion proteins. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[72]  S. Prusiner Novel proteinaceous infectious particles cause scrapie. , 1982, Science.

[73]  I. Pattison,et al.  Modification of a strain of mouse-adapted scrapie by passage through rats. , 1968, Research in veterinary science.

[74]  H. Fraser,et al.  Identification of a gene which controls the incubation period of some strains of scrapie agent in mice. , 1968, Journal of comparative pathology.