Atrial natriuretic peptide and atrial size during normal pregnancy

Summary. Plasma atrial natriuretic peptide (ANP), right and left atrial areas and the diameter of the left atrium were studied serially during normal pregnancy and at 6 weeks post partum in 21 nulliparous women. Concentrations of ANP in plasma were significantly elevated during mid-pregnancy. Thereafter ANP levels were not significantly different from those at 6 weeks after delivery. All atrial measurements were significantly increased in the third trimester of pregnancy, but none was significantly correlated with the plasma ANP concentrations. This might point at an altered mechanism of ANP secretion, which may be part of a physiological adaptive process to sustain the hypervolaemia of pregnancy.

[1]  H. Kreuzer,et al.  [Determination of left atrial size. Comparison between echocardiographic and radiological determination]. , 2008, Deutsche Medizinische Wochenschrift.

[2]  P. R. Hein,et al.  Effects of dietary sodium restriction and posture on plasma levels of atrial natriuretic peptide, aldosterone and free aldosterone in normal human pregnancy. , 1990, The Journal of endocrinology.

[3]  J. Laragh,et al.  Atrial natriuretic factor in normal and hypertensive pregnancy. , 1989, American journal of obstetrics and gynecology.

[4]  S. Miyamoto,et al.  Circadian rhythm of plasma atrial natriuretic peptide, aldosterone, and blood pressure during the third trimester in normal and preeclamptic pregnancies , 1988, American journal of obstetrics and gynecology.

[5]  R. Maiorca,et al.  Effects of changes in intravascular volume on atrial size and plasma levels of immunoreactive atrial natriuretic peptide in uremic man. , 1988, Clinical nephrology.

[6]  M. Pandian,et al.  Atrial natriuretic peptide and arginine vasopressin in pregnancy and pregnancy-induced hypertension. , 1988, Nephron.

[7]  T. Yamaji,et al.  Plasma levels of atrial natriuretic peptide during normal pregnancy and in pregnancy complicated by hypertension. , 1988, American journal of obstetrics and gynecology.

[8]  P. Dandona,et al.  Secretion of atrial natriuretic peptide and digoxin-like immunoreactive substance during pregnancy. , 1988, Clinical chemistry.

[9]  I. Macgillivray,et al.  The classification and definition of the hypertensive disorders of pregnancy. , 1988, American journal of obstetrics and gynecology.

[10]  G. Thamsborg,et al.  Increased concentration of circulating atrial natriuretic peptide during normal pregnancy. , 1988, European journal of obstetrics, gynecology, and reproductive biology.

[11]  T. Hedner,et al.  Plasma Atrial Natriuretic Peptide (Anp) And Maternal Hemodynamic Changes During Normal Pregnancy , 1988, Acta obstetricia et gynecologica Scandinavica.

[12]  S. Hunter,et al.  Haemodynamic changes during the puerperium: a Doppler and M‐mode echocardiographic study , 1987, British journal of obstetrics and gynaecology.

[13]  P. R. Hein,et al.  Plasma atrial natriuretic peptide (ANP) in late pregnancy and puerperium. , 1987, European journal of obstetrics, gynecology, and reproductive biology.

[14]  P. R. Hein,et al.  The influence of human maternal exercise on the uteroplacental circulation and the fetal heart rate , 1987 .

[15]  O. Tanizawa,et al.  Changes in concentration of human atrial natriuretic peptide in normal pregnancy and toxaemia. , 1987, The Journal of endocrinology.

[16]  S. Hunter,et al.  LEFT ATRIAL DIMENSION DURING EARLY PUERPERIUM , 1987, The Lancet.

[17]  T. Benraad,et al.  A sensitive radioimmunoassay of atrial natriuretic peptide in human plasma, using a tracer with an immobilized glycouril agent. , 1987, Clinica chimica acta; international journal of clinical chemistry.

[18]  A. Hofman,et al.  Determinants of rise in blood pressure in normotensive children. , 1987, Journal of hypertension.

[19]  P. R. Hein,et al.  ATRIAL NATRIURETIC PEPTIDE CONCENTRATIONS DURING PREGNANCY , 1987, The Lancet.

[20]  A. Abdulla,et al.  Serial noninvasive evaluation of cardiovascular hemodynamics during pregnancy. , 1987, American journal of obstetrics and gynecology.

[21]  S. Bloom,et al.  RELEASE OF ATRIAL NATRIURETIC PEPTIDE DURING PREGNANCY AND IMMEDIATE PUERPERIUM , 1987, The Lancet.

[22]  R. Rodeheffer,et al.  Atrial pressure and secretion of atrial natriuretic factor into the human central circulation. , 1986, Journal of the American College of Cardiology.

[23]  M. Lesch,et al.  Limited proteolysis of rabbit cardiac procathepsin D in a cell-free system. , 1986, The American journal of physiology.

[24]  H. Büller,et al.  Serial impedance plethysmography for suspected deep venous thrombosis in outpatients. The Amsterdam General Practitioner Study. , 1986, The New England journal of medicine.

[25]  E. Rey,et al.  Plasma concentration of atrial natriuretic factor in normal pregnancy. , 1985, The New England journal of medicine.

[26]  F. Takaku,et al.  Atrial natriuretic factor in human blood. , 1985, The Journal of clinical investigation.

[27]  F Hytten,et al.  Blood Volume Changes in Normal Pregnancy , 1985, Clinics in haematology.

[28]  J. R. Ledsome,et al.  Release of atrial natriuretic peptide by atrial distension. , 1985, Canadian journal of physiology and pharmacology.

[29]  H. Allen,et al.  Real-time Cross-sectional Echocardiographic Imaging and Measurement of the Patent Ductus Arteriosus in Infants and Children , 1978, Circulation.

[30]  E. Braunwald,et al.  HEMODYNAMICS AT REST AND DURING EXERCISE IN NORMAL PREGNANCY AS STUDIED BY CARDIAC CATHETERIZATION , 1955 .

[31]  P. R. Hein,et al.  Atrial Natriuretic Peptide (ANP) in Normal Pregnancy; A Longitudinal Study , 1990 .

[32]  S. Boschi,et al.  Plasma concentrations of atrial natriuretic factor in normal pregnancy and early puerperium. , 1989, Clinical and experimental hypertension. Part A, Theory and practice.

[33]  A. Fournier,et al.  Atrial natriuretic factor in pregnancy-induced hypertension and preeclampsia: increased plasma concentrations possibly explaining these hypovolemic states with paradoxical hyporeninism. , 1988, American journal of hypertension.