Infant Pyogenic Liver Abscess Complicated With Autoimmune Neutropenia: Two Cases.

Approximately 90% of patients with autoimmune neutropenia (AIN) suffer from mild infections although neutrophil count often decreases to <500/μL. Here, we report 2 cases of infant pyogenic liver abscess complicated with AIN. We should consider the possibility of AIN as an underlying disease when diagnosing pyogenic liver abscess during childhood.

[1]  M. Taghinejad,et al.  High Frequency of Aichivirus in Children With Acute Gastroenteritis in Iran. , 2020, The Pediatric infectious disease journal.

[2]  A. Ishiguro,et al.  Chronic Neutropenia in Children With Abscess Forming Cervical Lymphadenitis Caused by Staphylococcus aureus , 2019, The Pediatric infectious disease journal.

[3]  R. Saxena,et al.  Protocol-based management of 154 cases of pediatric liver abscess , 2017, Pediatric Surgery International.

[4]  K. Schwarz,et al.  Liver Abscess Complicated by Diaphragm Perforation and Pleural Empyema Leads to the Discovery of Interleukin-1 Receptor-associated Kinase 4 Deficiency , 2014, The Pediatric infectious disease journal.

[5]  N. Borregaard.  Severe congenital neutropenia: new lane for ELANE. , 2014, Blood.

[6]  T. Lamy,et al.  Autoimmune neutropenia. , 2014, Presse medicale.

[7]  Douglas R. McDonald,et al.  Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency , 2010, Medicine.

[8]  J. Bux,et al.  Human neutrophil alloantigens , 2008, Vox sanguinis.

[9]  G. Mieli-Vergani,et al.  Liver Abscesses in Children: A Single Center Experience in the Developed World , 2006, Journal of pediatric gastroenterology and nutrition.

[10]  S. Skoda-Smith,et al.  Persistent Perianal Abscess in Early Infancy as a Presentation of Autoimmune Neutropenia , 2003, Journal of Perinatology.

[11]  K. Welte,et al.  Diagnosis and clinical course of autoimmune neutropenia in infancy: analysis of 240 cases. , 1998, Blood.