Poly (ADP-ribose) polymerases 16 triggers pathological cardiac hypertrophy via activating IRE1α–sXBP1–GATA4 pathway

[1]  Qingbo Xu,et al.  Unspliced XBP1 Counteracts β-Catenin to Inhibit Vascular Calcification , 2021, Circulation research.

[2]  Michael S. Cohen,et al.  The non-canonical target PARP16 contributes to polypharmacology of the PARP inhibitor talazoparib and its synergy with WEE1 inhibitors. , 2021, Cell chemical biology.

[3]  Gang Wei,et al.  SMYD3–PARP16 axis accelerates unfolded protein response and mediates neointima formation , 2020, Acta pharmaceutica Sinica. B.

[4]  Jiaxue Wu,et al.  Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging , 2020, Aging.

[5]  J. Ge,et al.  Pressure overload promotes cystatin C secretion of cardiomyocytes to regulate the MAPK signaling pathway and mediate cardiac hypertrophy , 2020, Annals of translational medicine.

[6]  W. Hong,et al.  Histone methyltransferase Smyd3 is a new regulator for vascular senescence , 2020, Aging cell.

[7]  Bingying Zhou,et al.  Single-Cell Reconstruction of Progression Trajectory Reveals Intervention Principles in Pathological Cardiac Hypertrophy , 2020, Circulation.

[8]  Yan Zhang,et al.  STING is an essential regulator of heart inflammation and fibrosis in mice with pathological cardiac hypertrophy via endoplasmic reticulum (ER) stress. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[9]  C. Dieterich,et al.  ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb , 2019, Circulation research.

[10]  M. Jeong,et al.  Dendropanax morbifera Prevents Cardiomyocyte Hypertrophy by Inhibiting the Sp1/GATA4 Pathway. , 2018, The American journal of Chinese medicine.

[11]  Qiuyun Chen,et al.  A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure , 2017, Nature Communications.

[12]  Wenbo Yu,et al.  Epigallocatechin-3-gallate enhances ER stress-induced cancer cell apoptosis by directly targeting PARP16 activity , 2017, Cell Death Discovery.

[13]  W. Gong,et al.  MicroRNA regulation of unfolded protein response transcription factor XBP1 in the progression of cardiac hypertrophy and heart failure in vivo , 2015, Journal of Translational Medicine.

[14]  Joseph A. Hill,et al.  Protein quality control and metabolism: bidirectional control in the heart. , 2015, Cell metabolism.

[15]  J. Zou,et al.  PARP-2 knockdown protects cardiomyocytes from hypertrophy via activation of SIRT1. , 2013, Biochemical and biophysical research communications.

[16]  M. Jwa,et al.  PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK and IRE1α-mediated unfolded protein response , 2012, Nature Cell Biology.

[17]  C. Carlson,et al.  Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes. , 2011, Journal of applied physiology.

[18]  C. Orosz,et al.  Serum response factor neutralizes Pur alpha- and Pur beta-mediated repression of the fetal vascular smooth muscle alpha-actin gene in stressed adult cardiomyocytes. , 2008, American journal of physiology. Cell physiology.

[19]  S. Ikeda,et al.  Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure , 2006, Proceedings of the National Academy of Sciences.

[20]  R. Schwartz,et al.  Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability , 2006, Circulation research.

[21]  V. Jeevanandam,et al.  Increased expression of poly(ADP-ribose) polymerase-1 contributes to caspase-independent myocyte cell death during heart failure. , 2005, American journal of physiology. Heart and circulatory physiology.

[22]  E. Olson,et al.  Cardiac hypertrophy: the good, the bad, and the ugly. , 2003, Annual review of physiology.

[23]  I. Komuro,et al.  Roles of cardiac transcription factors in cardiac hypertrophy. , 2003, Circulation research.

[24]  J. Molkentin.  The Zinc Finger-containing Transcription Factors GATA-4, -5, and -6 , 2000, The Journal of Biological Chemistry.

[25]  H. Hakonarson,et al.  GATA factors promote ER integrity and β-cell survival and contribute to type 1 diabetes risk. , 2014, Molecular endocrinology.