Optical and thermal properties in ultrafast laser surface nanostructuring on biodegradable polymer

We investigate the effect of optical and thermal properties in laser-induced periodic surface structures (LIPSS) formation on a poly-L-lactic acid (PLLA), a biodegradable polymer. Surface properties of biomaterials are known to be one of the key factors in tissue engineering. Methods to process biomaterial surfaces have been studied widely to enhance cell adhesive and anisotropic properties. LIPSS formation has advantages in a dry processing which is able to process complex-shaped surfaces without using a toxic chemical component. LIPSS, however, was difficult to be formed on PLLA due to its thermal and optical properties compared to other polymers. To obtain new perspectives in effect of these properties above, LIPSS formation dependences on wavelength, pulse duration and repetition rate have been studied. At 800 nm of incident wavelength, high-spatial frequency LIPSS (HSFL) was formed after applying 10000 femtosecond pulses at 1.0 J/cm2 in laser fluence. At 400 nm of the wavelength, HSFL was formed at fluences higher than 0.20 J/cm2 with more than 3000 pulses. Since LIPSS was less formed with lower repetition rate, certain heat accumulation may be required for LIPSS formation. With the pulse duration of 2.0 ps, higher laser fluence as well as number of pulses compared to the case of 120 fs was necessary. This indicates that multiphoton absorption process is essential for LIPSS formation. Study on biodegradation modification was also performed.

[1]  Shaochen Chen,et al.  Micro and nano-fabrication of biodegradable polymers for drug delivery. , 2004, Advanced drug delivery reviews.

[2]  Razvan Stoian,et al.  Periodic nanoscale structures on polyimide surfaces generated by temporally tailored femtosecond laser pulses. , 2011, Physical chemistry chemical physics : PCCP.

[3]  A Curtis,et al.  Topographical control of cells. , 1997, Biomaterials.

[4]  Alyssa Panitch,et al.  Polymeric biomaterials for tissue and organ regeneration , 2001 .

[5]  Alexander A. Oraevsky,et al.  Two-photon ionization and dissociation of liquid water by powerful laser UV radiation , 1983 .

[6]  A. Ahluwalia,et al.  Fabrication of PLGA scaffolds using soft lithography and microsyringe deposition. , 2003, Biomaterials.

[7]  S. Lazare,et al.  Large scale excimer laser production of submicron periodic structures on polymer surfaces , 1993 .

[8]  Mohamed Oujja,et al.  Laser-induced periodic surface structuring of biopolymers , 2013 .

[9]  Shaochen Chen,et al.  Direct micro-patterning of biodegradable polymers using ultraviolet and femtosecond lasers. , 2005, Biomaterials.

[10]  C. Wilkinson,et al.  Topographical control of cell behaviour: II. Multiple grooved substrata. , 1990, Development.

[11]  V. Siracusa,et al.  High-resolution X-ray photoelectron spectroscopy of crystalline and amorphous poly(ethylene terephthalate): a study of biaxially oriented film, spin cast film and polymer melt , 1996 .

[12]  A. Salazar,et al.  Nano- and microstructural effects on thermal properties of poly (l-lactide)/multi-wall carbon nanotube composites , 2012 .

[13]  Makoto Sasaki,et al.  Fabrication of nano-periodic structure for water repellent using femtosecond laser , 2011, 2011 IEEE International Conference on Robotics and Biomimetics.

[14]  L. Visai,et al.  Biodegradable microgrooved polymeric surfaces obtained by photolithography for skeletal muscle cell orientation and myotube development. , 2010, Acta biomaterialia.

[15]  Fumiyo Yoshino,et al.  Heat accumulation effects in femtosecond laser-written waveguides with variable repetition rate. , 2005, Optics express.

[16]  Morphological Observations of Mesenchymal Stem Cell Adhesion to a Nanoperiodic-Structured Titanium Surface Patterned Using Femtosecond Laser Processing , 2012 .

[17]  Wolfgang Kautek,et al.  Ablation experiments on polyimide with femtosecond laser pulses , 1999 .

[18]  J. A. Pérez-Hernández,et al.  Ultraviolet and infrared femtosecond laser induced periodic surface structures on thin polymer films , 2012 .

[19]  C. Wilkinson,et al.  The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. , 2007, Nature materials.

[20]  Jörg Krüger,et al.  Femtosecond laser-induced periodic surface structures , 2012 .

[21]  Z. Bao,et al.  Organic Thin‐Film Transistors Fabricated on Resorbable Biomaterial Substrates , 2010, Advanced materials.

[22]  Guoqiang Xie,et al.  Cell spreading on titanium dioxide film formed and modified with aerosol beam and femtosecond laser , 2014 .

[23]  Holger Lubatschowski,et al.  Repetition rate dependency of low-density plasma effects during femtosecond-laser-based surgery of biological tissue , 2009 .

[24]  A. Bruinink,et al.  The effect of topographic characteristics on cell migration velocity. , 2006, Biomaterials.