Response Surface Methodology for Optimization of Process Variables of Preparation of Atorvastatin Suspension by Microprecipitation Method Using Desirability Function

Maryam Maghsoodi1, 2, Seyed Hassan Montazam3, Hussein Rezvantalab4, Mitra Jelvehgari*1,2 1Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran 2Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran 3Department of Microbiology, Bonab Branch, Islamic Azad University, Bonab, Iran 4Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran

[1]  Waseem Kaialy,et al.  Recent advances in the engineering of nanosized active pharmaceutical ingredients: Promises and challenges. , 2016, Advances in colloid and interface science.

[2]  Alejandro Sosnik,et al.  Advantages and challenges of the spray-drying technology for the production of pure drug particles and drug-loaded polymeric carriers. , 2015, Advances in colloid and interface science.

[3]  Pooja D. Vaghela,et al.  Role of excipients in the crystallization of Albendazole , 2015 .

[4]  H. Valizadeh,et al.  Experimental Design to Predict Process Variables in the Microcrystals of Celecoxib for Dissolution Rate Enhancement Using Response Surface Methodology. , 2015, Advanced pharmaceutical bulletin.

[5]  V. Junyaprasert,et al.  Nanocrystals for enhancement of oral bioavailability of poorly water-soluble drugs , 2015 .

[6]  Prakash Khadka,et al.  Pharmaceutical particle technologies: An approach to improve drug solubility, dissolution and bioavailability , 2014 .

[7]  M. K. Chourasia,et al.  Engineered nanocrystal technology: in-vivo fate, targeting and applications in drug delivery. , 2014, Journal of controlled release : official journal of the Controlled Release Society.

[8]  M. Raval,et al.  Design and development of solid nanoparticulate dosage forms of telmisartan for bioavailability enhancement by integration of experimental design and principal component analysis , 2014 .

[9]  Rainer H. Müller,et al.  Bottom-up approaches for preparing drug nanocrystals: formulations and factors affecting particle size. , 2013, International journal of pharmaceutics.

[10]  E. Lee,et al.  Effect of particle size on the dissolution behaviors of poorly water-soluble drugs , 2012, Archives of pharmacal research.

[11]  F. Espitalier,et al.  An innovative antisolvent precipitation process as a promising technique to prepare ultrafine rifampicin particles , 2012 .

[12]  Alpana Ankush Thorat,et al.  Liquid antisolvent precipitation and stabilization of nanoparticles of poorly water soluble drugs in aqueous suspensions: Recent developments and future perspective , 2012 .

[13]  Koichi Wada,et al.  Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: basic approaches and practical applications. , 2011, International journal of pharmaceutics.

[14]  S. Byrn,et al.  Extraction and Physicochemical Characterization of a New Polysaccharide Obtained from the Fresh Fruits of Abelmoschus Esculentus , 2011, Iranian journal of pharmaceutical research : IJPR.

[15]  I. Ghosh,et al.  Nanosuspension for improving the bioavailability of a poorly soluble drug and screening of stabilizing agents to inhibit crystal growth. , 2011, International journal of pharmaceutics.

[16]  Y. Krishnaiah.  Pharmaceutical Technologies for Enhancing Oral Bioavailability of Poorly Soluble Drugs , 2010 .

[17]  Kaan Yetilmezsoy,et al.  Response surface modeling of Pb(II) removal from aqueous solution by Pistacia vera L.: Box-Behnken experimental design. , 2009, Journal of hazardous materials.

[18]  Yuan Le,et al.  Micronization of atorvastatin calcium by antisolvent precipitation process. , 2009, International journal of pharmaceutics.

[19]  Dianrui Zhang,et al.  Drug nanocrystals for the formulation of poorly soluble drugs and its application as a potential drug delivery system , 2008 .

[20]  A. Fahr,et al.  Drug delivery strategies for poorly water-soluble drugs , 2007, Expert opinion on drug delivery.

[21]  A. Nokhodchi,et al.  Improved Compaction and Packing Properties of Naproxen Agglomerated Crystals Obtained by Spherical Crystallization Technique , 2007, Drug development and industrial pharmacy.

[22]  L. Gauckler,et al.  Stabilization of foams with inorganic colloidal particles. , 2006, Langmuir : the ACS journal of surfaces and colloids.

[23]  Colin W Pouton,et al.  Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system. , 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[24]  Hans P Merkle,et al.  Microencapsulation by solvent extraction/evaporation: reviewing the state of the art of microsphere preparation process technology. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[25]  J E Kipp,et al.  The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs. , 2004, International journal of pharmaceutics.

[26]  N. Rasenack,et al.  Micron‐Size Drug Particles: Common and Novel Micronization Techniques , 2004, Pharmaceutical development and technology.

[27]  N. Rasenack,et al.  Microcrystals for dissolution rate enhancement of poorly water-soluble drugs. , 2003, International journal of pharmaceutics.

[28]  J Dressman,et al.  Improving drug solubility for oral delivery using solid dispersions. , 2000, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[29]  E. Reverchon.  SUPERCRITICAL ANTISOLVENT PRECIPITATION OF MICRO- AND NANO-PARTICLES , 1999 .

[30]  R. Grover,et al.  In vitro release evaluation of hydrocortisone liquisolid tablets. , 1998, Journal of pharmaceutical sciences.

[31]  Rainer H. Müller,et al.  Nanosuspensions for the formulation of poorly soluble drugs: I. Preparation by a size-reduction technique , 1998 .

[32]  Chang Hyun Ko,et al.  Disordered molecular sieve with branched mesoporous channel network , 1996 .

[33]  Mitra Mosharraf,et al.  The effect of particle size and shape on the surface specific dissolution rate of microsized practically insoluble drugs , 1995 .

[34]  P Ruelle,et al.  Hydrophobic effect at the origin of the low solubility of inert solid substances in hydrogen-bonded solvents. , 1994, Journal of pharmaceutical sciences.

[35]  Formulations and evaluation of oral delivery systems of poorly absorbed drugs used in osteoporosis , 2016 .

[36]  Aron H Blaesi,et al.  The design and manufacture of immediate-release optimal solid dosage forms , 2014 .

[37]  T. Soni,et al.  Formulation and Physical characterization of microcrystals for dissolution rate enhancement of Tolbutamide , 2010 .

[38]  Rainer H Müller,et al.  Drug nanocrystals of poorly soluble drugs produced by high pressure homogenisation. , 2006, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[39]  H. Lennernäs.  Clinical Pharmacokinetics of Atorvastatin , 2003, Clinical pharmacokinetics.

[40]  Paul A. Webb,et al.  Volume and Density Determinations for Particle Technologists , 2001 .