NADH oxidase activity of Bacillus subtilis nitroreductase NfrA1: Insight into its biological role

MINT‐7990140: nfrA1 (uniprotkb:P39605) and nfrA1 (uniprotkb:P39605) bind (MI:0407) by X‐ray crystallography (MI:0114)

[1]  Identification of Regulatory Domains in ADP-ribosyltransferase-1 That Determine Transferase and NAD Glycohydrolase Activities* , 2003, Journal of Biological Chemistry.

[2]  D. Kerr,et al.  NITROREDUCTASE: A PRODRUG‐ACTIVATING ENZYME FOR CANCER GENE THERAPY , 2004, Clinical and experimental pharmacology & physiology.

[3]  R. Marmorstein,et al.  Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[4]  B. Matthews Solvent content of protein crystals. , 1968, Journal of molecular biology.

[5]  K. Gruber,et al.  Structure and function of YcnD from Bacillus subtilis, a flavin-containing oxidoreductase. , 2005, Biochemistry.

[6]  E. Wolvetang,et al.  Apoptosis induced by inhibitors of the plasma membrane NADH-oxidase involves Bcl-2 and calcineurin. , 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[7]  Serge X. Cohen,et al.  Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7 , 2008, Nature Protocols.

[8]  A. Labigne,et al.  Evaluation of Nitrofurantoin Combination Therapy of Metronidazole-Sensitive and -Resistant Helicobacter pyloriInfections in Mice , 2000, Antimicrobial Agents and Chemotherapy.

[9]  Collaborative Computational,et al.  The CCP4 suite: programs for protein crystallography. , 1994, Acta crystallographica. Section D, Biological crystallography.

[10]  Thomas C Terwilliger,et al.  Automated structure solution, density modification and model building. , 2002, Acta crystallographica. Section D, Biological crystallography.

[11]  F. Rafii,et al.  Isolation of Nitrofurantoin-Resistant Mutants of Nitroreductase-Producing Clostridium sp. Strains from the Human Intestinal Tract , 1998, Antimicrobial Agents and Chemotherapy.

[12]  R. Allmansberger,et al.  Transcription of the nfrA-ywcH Operon from Bacillus subtilis Is Specifically Induced in Response to Heat , 2000, Journal of bacteriology.

[13]  G. Lutty,et al.  Increased NADH oxidase activity in the retina of the BBZ/Wor diabetic rat. , 1998, Free radical biology & medicine.

[14]  V. Massey The chemical and biological versatility of riboflavin. , 2000, Biochemical Society transactions.

[15]  K. Saigo,et al.  Purification and characterization of NfrA1, a Bacillus subtilis nitro/flavin reductase capable of interacting with the bacterial luciferase. , 1998, Bioscience, biotechnology, and biochemistry.

[16]  K. Saigo,et al.  Structure and site-directed mutagenesis of a flavoprotein from Escherichia coli that reduces nitrocompounds: alteration of pyridine nucleotide binding by a single amino acid substitution. , 2001, The Journal of biological chemistry.

[17]  Hege S. Beard,et al.  Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening. , 2004, Journal of medicinal chemistry.

[18]  N. Oppenheimer NAD hydrolysis: Chemical and enzymatic mechanisms , 1994, Molecular and Cellular Biochemistry.

[19]  Han-Bok Kim,et al.  Vibrio harveyi Nitroreductase Is Also a Chromate Reductase , 2003, Applied and Environmental Microbiology.

[20]  F. Lund Signaling Properties of CD38 in the Mouse Immune System: Enzyme-dependent and -independent Roles in Immunity , 2006, Molecular medicine.

[21]  R. Schmid,et al.  Crystal structure of NADH oxidase from Thermus thermophilus , 1995, Nature Structural Biology.

[22]  R. Levine,et al.  Methionine in proteins defends against oxidative stress , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[23]  J. Tanner,et al.  Unusual folded conformation of nicotinamide adenine dinucleotide bound to flavin reductase P , 1999, Protein science : a publication of the Protein Society.

[24]  G. Sheldrick A short history of SHELX. , 2008, Acta crystallographica. Section A, Foundations of crystallography.

[25]  S. Padmaja,et al.  The reaction of no with superoxide. , 1993, Free radical research communications.

[26]  R J Read,et al.  Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.

[27]  D. M. Morré,et al.  Role of membrane redox in aging-related diseases , 2006 .

[28]  Patrice Gouet,et al.  ESPript: analysis of multiple sequence alignments in PostScript , 1999, Bioinform..

[29]  F. Halgand,et al.  Purification and identification of a Bacillus nitroreductase : Potential use in 3,5-DNBTF biosensoring system , 2006 .

[30]  H. Abruña,et al.  Amperometric TNT biosensor based on the oriented immobilization of a nitroreductase maltose binding protein fusion. , 2002, Analytical chemistry.

[31]  Matthew P. Repasky,et al.  Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy. , 2004, Journal of medicinal chemistry.

[32]  Szegedi Tudományegyetem Acta biologica Szegediensis , 2000 .

[33]  J. Podczasy,et al.  Reduction of iodonitrotetrazolium violet by superoxide radicals. , 1988, Biochemical and biophysical research communications.

[34]  J. Tanner,et al.  Flavin reductase P: structure of a dimeric enzyme that reduces flavin. , 1996, Biochemistry.

[35]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[36]  D. Harrison,et al.  Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system. , 1999, Circulation.

[37]  M. Calzi,et al.  Streptococcus mutans H2O2-forming NADH oxidase is an alkyl hydroperoxide reductase protein. , 2000, Free radical biology & medicine.

[38]  Wolfgang Kabsch,et al.  Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants , 1993 .

[39]  J. Cashman,et al.  Human flavin-containing monooxygenases. , 2006, Annual review of pharmacology and toxicology.

[40]  G. Bricogne,et al.  Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT. , 2004, Acta crystallographica. Section D, Biological crystallography.

[41]  V. Schramm,et al.  Transition State Structure for the Hydrolysis of NAD Catalyzed by Diphtheria Toxin. , 1997, Journal of the American Chemical Society.

[42]  R. Boyle,et al.  Hypoxia: targeting the tumour. , 2006, Anti-cancer agents in medicinal chemistry.

[43]  J. Repine,et al.  Hydrogen peroxide mediated killing of bacteria , 1982, Molecular and Cellular Biochemistry.

[44]  J C Spain,et al.  Biodegradation of nitroaromatic compounds. , 2013, Annual review of microbiology.

[45]  S. Hirayama,et al.  Relationship between the redox change in yellow fluorescent protein of Vibrio fischeri strain Y1 and the reversible change in color of bioluminescence in vitro. , 2007, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[46]  Conrad C. Huang,et al.  UCSF Chimera—A visualization system for exploratory research and analysis , 2004, J. Comput. Chem..

[47]  B. Giardina,et al.  Direct NAD(P)H hydrolysis into ADP-ribose(P) and nicotinamide induced by reactive oxygen species: A new mechanism of oxygen radical toxicity , 2000, Free radical research.