Ultrasound-enhanced transgene expression in vascular cells is not dependent upon cavitation-induced free radicals.

[1]  K. Tachibana,et al.  Induction of reparative dentin formation by ultrasound-mediated gene delivery of growth/differentiation factor 11. , 2003, Human gene therapy.

[2]  Y. Tabata,et al.  Ultrasound enhances the transfection of plasmid DNA by non-viral vectors. , 2003, Current pharmaceutical biotechnology.

[3]  T. Partridge,et al.  Microbubble ultrasound improves the efficiency of gene transduction in skeletal muscle in vivo with reduced tissue damage , 2003, Gene Therapy.

[4]  Jonathan R. Lindner,et al.  Noninvasive Assessment of Angiogenesis by Ultrasound and Microbubbles Targeted to &agr;v-Integrins , 2003, Circulation.

[5]  J. Lindner.  Evolving applications for contrast ultrasound. , 2002, The American journal of cardiology.

[6]  J. Quddus,et al.  Diagnostic ultrasound-induced membrane damage in phagocytic cells loaded with contrast agent and its relation to Doppler-mode images , 2002, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[7]  R. Mulligan,et al.  Genetic interventions for vein bypass graft disease: a review. , 2002, Journal of vascular surgery.

[8]  J. Isner,et al.  Transcutaneous ultrasound augments naked DNA transfection of skeletal muscle. , 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

[9]  Paul A Dayton,et al.  Targeted imaging using ultrasound , 2002, Journal of magnetic resonance imaging : JMRI.

[10]  Douglas L. Miller,et al.  Lithotripter shock waves with cavitation nucleation agents produce tumor growth reduction and gene transfer in vivo. , 2002, Ultrasound in medicine & biology.

[11]  S. Kaul,et al.  Contrast Ultrasound Targeted Drug and Gene Delivery: An Update on a New Therapeutic Modality , 2002, Journal of cardiovascular pharmacology and therapeutics.

[12]  Shigekazu Fukuda,et al.  Effects of dissolved gases and an echo contrast agent on ultrasound mediated in vitro gene transfection. , 2002, Ultrasonics sonochemistry.

[13]  B. Gersh,et al.  Defining gene transfer before expecting gene therapy: putting the horse before the cart. , 2002, Circulation.

[14]  R. Shohet,et al.  DNA-loaded albumin microbubbles enhance ultrasound-mediated transfection in vitro. , 2002, Ultrasound in medicine & biology.

[15]  R. Busse,et al.  Vascular Gene Transfer of Phosphomimetic Endothelial Nitric Oxide Synthase (S1177D) Using Ultrasound-Enhanced Destruction of Plasmid-Loaded Microbubbles Improves Vasoreactivity , 2002, Circulation.

[16]  Y. Taniyama,et al.  Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle , 2002, Gene Therapy.

[17]  S. Rajagopalan,et al.  Ultrasound-mediated transfection of canine myocardium by intravenous administration of cationic microbubble-linked plasmid DNA. , 2002, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[18]  J. Chiu,et al.  Optical and atomic force microscopic studies on sonoporation. , 2002, The Journal of the Acoustical Society of America.

[19]  Junru Wu,et al.  Reparable sonoporation generated by microstreaming. , 2002, The Journal of the Acoustical Society of America.

[20]  E. Unger,et al.  Local drug and gene delivery through microbubbles. , 2001, Progress in cardiovascular diseases.

[21]  M. Dake,et al.  High-efficiency endovascular gene delivery via therapeutic ultrasound. , 2001, Journal of the American College of Cardiology.

[22]  S. Kaul,et al.  Delivery of Drugs with Ultrasound , 2001, Echocardiography.

[23]  T. Porter,et al.  Therapeutic Ultrasound for Gene Delivery , 2001, Echocardiography.

[24]  D. Cumberland,et al.  Ultrasound Gene Therapy: On the Road from Concept to Reality , 2001, Echocardiography.

[25]  D. Crossman,et al.  Microbubble-enhanced ultrasound for vascular gene delivery , 2000, Gene Therapy.

[26]  Junru Wu,et al.  Experimental study of the effects of Optison concentration on sonoporation in vitro. , 2000, Ultrasound in medicine & biology.

[27]  M. Nakamura,et al.  Ultrasound facilitates transduction of naked plasmid DNA into colon carcinoma cells in vitro and in vivo. , 2000, Human gene therapy.

[28]  N. Rainov,et al.  Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation effects. , 2000, Ultrasound in medicine & biology.

[29]  E. Kiss-Toth,et al.  A novel mammalian expression screen exploiting green fluorescent protein-based transcription detection in single cells. , 2000, Journal of immunological methods.

[30]  Morton W. Miller,et al.  Gene transfection and drug delivery. , 2000, Ultrasound in medicine & biology.

[31]  S. Barnett.  Biophysical aspects of diagnostic ultrasound. , 2000, Ultrasound in medicine & biology.

[32]  Douglas L. Miller,et al.  Sonoporation of monolayer cells by diagnostic ultrasound activation of contrast-agent gas bodies. , 2000, Ultrasound in medicine & biology.

[33]  S. Ylä-Herttuala,et al.  Cardiovascular gene therapy , 2000, The Lancet.

[34]  Douglas L. Miller,et al.  Ultrasonic enhancement of gene transfection in murine melanoma tumors. , 1999, Ultrasound in medicine & biology.

[35]  J. Debus,et al.  A comparison of shock wave and sinusoidal-focused ultrasound-induced localized transfection of HeLa cells. , 1999, Ultrasound in medicine & biology.

[36]  A. Brayman,et al.  Transient poration and cell surface receptor removal from human lymphocytes in vitro by 1 MHz ultrasound. , 1999, Ultrasound in medicine & biology.

[37]  D. Cumberland,et al.  Ultrasound enhances reporter gene expression after transfection of vascular cells in vitro. , 1999, Circulation.

[38]  B. P. Wilson,et al.  Mechanistic and Spatial Study of Ultrasonically Induced Luminol Chemiluminescence , 1999 .

[39]  Junru Wu,et al.  Ultrasound-induced cell lysis and sonoporation enhanced by contrast agents. , 1999, The Journal of the Acoustical Society of America.

[40]  Koichi Ogawa,et al.  Induction of cell-membrane porosity by ultrasound , 1999, The Lancet.

[41]  N. Miyoshi,et al.  Effects of cysteamine and cystamine on the sonochemical accumulation of hydrogen peroxide--implications for their mechanisms of action in ultrasound-exposed cells. , 1999, Free radical biology & medicine.

[42]  D. Miller,et al.  Gas-body-based contrast agent enhances vascular bioeffects of 1.09 MHz ultrasound on mouse intestine. , 1998, Ultrasound in medicine & biology.

[43]  P. Riesz,et al.  Effect of gas-containing microspheres and echo contrast agents on free radical formation by ultrasound. , 1998, Free radical biology & medicine.

[44]  J F Greenleaf,et al.  Artificial cavitation nuclei significantly enhance acoustically induced cell transfection. , 1998, Ultrasound in medicine & biology.

[45]  K. March,et al.  Gene therapy for restenosis: getting nearer the heart of the matter. , 1998, Circulation research.

[46]  E. Unger,et al.  Ultrasound enhances gene expression of liposomal transfection. , 1997, Investigative radiology.

[47]  J F Greenleaf,et al.  Ultrasound-mediated transfection of mammalian cells. , 1996, Human gene therapy.

[48]  J. Ellwart,et al.  Permeabilization of the plasma membrane of L1210 mouse leukemia cells using lithotripter shock waves , 1994, The Journal of Membrane Biology.

[49]  P. Riesz,et al.  Free radical formation induced by ultrasound and its biological implications. , 1992, Free radical biology & medicine.

[50]  R. M. Thomas,et al.  A comparison of hemolytic and sonochemical activity of ultrasonic cavitation in a rotating tube. , 1992, Ultrasound in medicine & biology.

[51]  Hong Zhang,et al.  Extracellular reduction of alloxan results in oxygen radical‐mediated attack on plasma and lysosomal membranes , 1992, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[52]  J. Howl,et al.  Permeabilisation of the sarcolemma in mouse diaphragm exposed to Bay K 8644 in vitro: time course, dependence on Ca2+ and effects of enzyme inhibitors , 2004, Acta Neuropathologica.

[53]  S. Srivastava,et al.  The effect of oxidants on biomembranes and cellular metabolism , 2004, Molecular and Cellular Biochemistry.

[54]  P. Huber,et al.  In vitro and in vivo transfection of plasmid DNA in the Dunning prostate tumor R3327-AT1 is enhanced by focused ultrasound , 2000, Gene Therapy.

[55]  J. Fowlkes,et al.  Section 6‐‐mechanical bioeffects in the presence of gas‐carrier ultrasound contrast agents. American Institute of Ultrasound in Medicine. , 2000, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[56]  J. Morris,et al.  Sonoporation of cultured cells in the rotating tube exposure system. , 1999, Ultrasound in medicine & biology.

[57]  M. Garnett,et al.  Gene-delivery systems using cationic polymers. , 1999, Critical reviews in therapeutic drug carrier systems.

[58]  Douglas L. Miller,et al.  Transfection of a reporter plasmid into cultured cells by sonoporation in vitro. , 1997, Ultrasound in medicine & biology.

[59]  R. M. Thomas,et al.  Ultrasound contrast agents nucleate inertial cavitation in vitro. , 1995, Ultrasound in medicine & biology.

[60]  Z. Darżynkiewicz,et al.  Assays of cell viability: discrimination of cells dying by apoptosis. , 1994, Methods in cell biology.

[61]  J. Kehrer.  Free radicals as mediators of tissue injury and disease. , 1993, Critical reviews in toxicology.

[62]  S. Marklund,et al.  Effect of extracellularly generated free radicals on the plasma membrane permeability of isolated pancreatic B-cells. , 1986, The International journal of biochemistry.

[63]  Bo Olsson,et al.  Determination of hydrogen peroxide in a flow system with microperoxidase as catalyst for the luminol chemiluminescence reaction , 1982 .