Impact of treatment with recombinant human GH and IGF-I on visceral adipose tissue and glucose homeostasis in adults.
暂无分享,去创建一个
[1] L. Lönn,et al. Growth hormone treatment reduces abdominal visceral fat in postmenopausal women with abdominal obesity: a 12-month placebo-controlled trial. , 2005, The Journal of clinical endocrinology and metabolism.
[2] D. Dunger,et al. Changes in free rather than total insulin-like growth factor-I enhance insulin sensitivity and suppress endogenous peak growth hormone (GH) release following short-term low-dose GH administration in young healthy adults. , 2004, The Journal of clinical endocrinology and metabolism.
[3] D. Dunger,et al. Short-term low-dose growth hormone administration in subjects with impaired glucose tolerance and the metabolic syndrome: effects on beta-cell function and post-load glucose tolerance. , 2004, European journal of endocrinology.
[4] J. Stepan,et al. The effects of GH replacement in adult GH‐deficient patients: changes in body composition without concomitant changes in the adipokines and insulin resistance , 2004, Clinical endocrinology.
[5] Oksana Gavrilova,et al. Insulin resistance in the liver-specific IGF-1 gene-deleted mouse is abrogated by deletion of the acid-labile subunit of the IGF-binding protein-3 complex: relative roles of growth hormone and IGF-1 in insulin resistance. , 2003, Diabetes.
[6] M. Savage,et al. Insulin-Like Growth Factor (IGF)-I Gene Deletion , 2002, Reviews in Endocrine and Metabolic Disorders.
[7] D. Dunger,et al. Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study , 2002, The Lancet.
[8] J. Svensson,et al. Effects of seven years of GH-replacement therapy on insulin sensitivity in GH-deficient adults. , 2002, The Journal of clinical endocrinology and metabolism.
[9] F. Dominici,et al. Growth Hormone-Induced Alterations in the Insulin-Signaling System , 2002, Experimental biology and medicine.
[10] P. Sönksen,et al. Growth hormone replacement therapy for adults: into the new millennium. , 2002, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
[11] H. Pijl,et al. Altered neuroregulation of GH secretion in viscerally obese premenopausal women. , 2001, The Journal of clinical endocrinology and metabolism.
[12] J. Frystyk,et al. Liver-specific igf-1 gene deletion leads to muscle insulin insensitivity. , 2001, Diabetes.
[13] D. M. Rocha,et al. Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects. , 1999, Diabetes.
[14] H. Orskov,et al. The pharmacokinetics of free insulin-like growth factor-I in healthy subjects. , 1999, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
[15] D. Dunger,et al. Effects of low-dose recombinant human insulin-like growth factor-I on insulin sensitivity, growth hormone and glucagon levels in young adults with insulin-dependent diabetes mellitus. , 1998, Metabolism: clinical and experimental.
[16] D. Dunger,et al. Growth hormone insulin-like growth factor I axis in insulin-dependent diabetes mellitus. , 1996, Hormone research.
[17] D. Bauman,et al. Effects of bovine somatotropin and insulin on whole-body and hindlimb glucose metabolism in growing steers. , 1995, Journal of animal science.
[18] D. Clemmons,et al. Insulin-like growth factors and their binding proteins: biological actions. , 1995, Endocrine reviews.
[19] D. O'Neal,et al. The effect of 3 months of recombinant human growth hormone (GH) therapy on insulin and glucose-mediated glucose disposal and insulin secretion in GH-deficient adults: a minimal model analysis. , 1994, The Journal of clinical endocrinology and metabolism.
[20] H. Kaji,et al. Regulation of the Growth Hormone (GH) Receptor and GH-Binding Protein mRNA , 1994, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[21] B. Bengtsson,et al. Effects of treatment with recombinant human growth hormone on insulin sensitivity and glucose metabolism in adults with growth hormone deficiency. , 1993, Metabolism: clinical and experimental.
[22] D. Dunger,et al. The frequency and amplitude of growth hormone secretory episodes as determined by deconvolution analysis are increased in adolescents with insulin dependent diabetes mellitus and are unaffected by short‐term euglycaemia , 1993, Clinical endocrinology.
[23] U. Keller,et al. Effect of increasing doses of recombinant human insulin-like growth factor-I on glucose, lipid, and leucine metabolism in man. , 1992, The Journal of clinical endocrinology and metabolism.
[24] P. Butler,et al. Effects of a physiological growth hormone pulse on substrate metabolism in insulin-dependent (type 1) diabetic subjects. , 1992, The Journal of clinical endocrinology and metabolism.
[25] D. Dunger,et al. Contrasting metabolic effects of continuous and pulsatile growth hormone administration in young adults with Type 1 (insulin-dependent) diabetes mellitus , 1992, Diabetologia.
[26] U. Smith,et al. Characterization of the insulin-antagonistic effect of growth hormone in man , 1991, Diabetologia.
[27] R. Humbel,et al. Insulin-like growth factors I and II. , 1990, European journal of biochemistry.
[28] P. Sönksen,et al. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. , 1989, The New England journal of medicine.
[29] R. Eckel,et al. Insulinlike Growth Factor Action and Production in Adipocytes and Endothelial Cells From Human Adipose Tissue , 1989, Diabetes.
[30] W. Rutter,et al. Expression and characterization of a functional human insulin-like growth factor I receptor. , 1988, The Journal of biological chemistry.
[31] M. Press,et al. Growth hormone and metabolism. , 1988, Diabetes/metabolism reviews.
[32] K. Alberti,et al. Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man. , 1988, The Journal of clinical investigation.
[33] E. Froesch,et al. Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults. , 1987, The New England journal of medicine.
[34] M. Davidson. Effect of growth hormone on carbohydrate and lipid metabolism. , 1987, Endocrine reviews.
[35] C Collins,et al. Insulin‐like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. , 1986, The EMBO journal.
[36] W. Tamborlane,et al. Importance of raised growth hormone levels in mediating the metabolic derangements of diabetes. , 1984, The New England journal of medicine.
[37] L. Mandarino,et al. Effects of Growth Hormone on Insulin Action in Man: Mechanisms of Insulin Resistance, Impaired Suppression of Glucose Production, and Impaired Stimulation of Glucose Utilization , 1982, Diabetes.
[38] D. Wilson,et al. Both human pituitary growth hormone and recombinant DNA-derived human growth hormone cause insulin resistance at a postreceptor site. , 1982, The Journal of clinical endocrinology and metabolism.
[39] U. Adamson. On the diabetogenic effect of growth hormone in man: effects of growth hormone on glucagon and insulin secretion , 1981, European journal of clinical investigation.
[40] J. Campbell,et al. Metasomatotrophic diabetes and its induction: Basal insulin secretion and insulin release responses to glucose, glucagon, arginine and meals , 1980, Diabetologia.
[41] M. Davidson,et al. The effect of nicotinic acid on growth hormone-induced lipolysis and glucose intolerance. , 1973, The Journal of laboratory and clinical medicine.
[42] K. Johansen,et al. Diurnal patterns of blood glucose, serum free fatty acids, insulin, glucagon and growth hormone in normals and juvenile diabetics , 1970, Diabetologia.
[43] E. Newsholme,et al. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. , 1963, Lancet.
[44] B. Houssay. The Hypophysis and Metabolism , 1936 .
[45] D. Dunger,et al. Insulin-like growth factor I has a direct effect on glucose and protein metabolism, but no effect on lipid metabolism in type 1 diabetes. , 2004, The Journal of clinical endocrinology and metabolism.
[46] M. Bouxsein,et al. Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice. , 2004, The Journal of clinical investigation.
[47] T. Jørgensen,et al. Heart Disease : A Population-Based Case-Control Study Low Serum Insulin-Like Growth Factor I Is Associated With Increased Risk of Ischemic , 2002 .
[48] K. Højlund,et al. Development and clinical evaluation of a novel immunoassay for the binary complex of IGF-I and IGF-binding protein-1 in human serum. , 2002, The Journal of clinical endocrinology and metabolism.
[49] S. Kira,et al. Relationship between reduced serum IGF-I levels and accumulation of visceral fat in Japanese men , 2002, International Journal of Obesity.
[50] D. Dunger,et al. Recombinant human insulin-like growth factor-I abolishes changes in insulin requirements consequent upon growth hormone pulsatility in young adults with type I diabetes mellitus. , 1998, Metabolism: clinical and experimental.
[51] J. Cunningham,et al. The effect of low dose recombinant human growth hormone replacement on regional fat distribution, insulin sensitivity, and cardiovascular risk factors in hypopituitary adults. , 1995, The Journal of clinical endocrinology and metabolism.
[52] R. Baxter,et al. Binding proteins for the insulin-like growth factors: structure, regulation and function. , 1989, Progress in growth factor research.
[53] L. Lönn,et al. Growth hormone treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism, and reduces diastolic blood pressure. , 1997, The Journal of clinical endocrinology and metabolism.