Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease.

[1]  L. Deldicque,et al.  Effect of acute environmental hypoxia on protein metabolism in human skeletal muscle , 2013, Acta physiologica.

[2]  E. Wouters,et al.  Synergistic stimulation of myogenesis by glucocorticoid and IGF-I signaling. , 2013, Journal of applied physiology.

[3]  M. Sandri,et al.  Role of autophagy in COPD skeletal muscle dysfunction. , 2013, Journal of applied physiology.

[4]  A. Schols,et al.  The mechanisms of cachexia underlying muscle dysfunction in COPD. , 2013, Journal of applied physiology.

[5]  F. Martinez,et al.  Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. , 2007, American journal of respiratory and critical care medicine.

[6]  M. Kjaer,et al.  Aging Affects the Transcriptional Regulation of Human Skeletal Muscle Disuse Atrophy , 2012, PloS one.

[7]  E. Wouters,et al.  NF-κB activation is required for the transition of pulmonary inflammation to muscle atrophy. , 2012, American journal of respiratory cell and molecular biology.

[8]  M. Pozzobon,et al.  Hypoxia Increases Mouse Satellite Cell Clone Proliferation Maintaining both In Vitro and In Vivo Heterogeneity and Myogenic Potential , 2012, PloS one.

[9]  Sally J. Singh,et al.  Inflammatory and satellite cells in the quadriceps of patients with COPD and response to resistance training. , 2012, Chest.

[10]  E. V. van Beek,et al.  Bone attenuation on routine chest CT correlates with bone mineral density on DXA in patients with COPD , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[11]  D. Rotin,et al.  The Ubiquitin Ligase Nedd4-1 Participates in Denervation-Induced Skeletal Muscle Atrophy in Mice , 2012, PloS one.

[12]  Roberto Bottinelli,et al.  The time course of the adaptations of human muscle proteome to bed rest and the underlying mechanisms , 2012, The Journal of physiology.

[13]  Yongmei Liu,et al.  The influence of abdominal visceral fat on inflammatory pathways and mortality risk in obstructive lung disease. , 2012, The American journal of clinical nutrition.

[14]  F. Maltais,et al.  MAPK signaling in the quadriceps of patients with chronic obstructive pulmonary disease. , 2012, Journal of applied physiology.

[15]  T. Speed,et al.  Genome-wide analysis of glucocorticoid receptor-binding sites in myotubes identifies gene networks modulating insulin signaling , 2012, Proceedings of the National Academy of Sciences.

[16]  F. Maltais,et al.  Satellite Cells Senescence in Limb Muscle of Severe Patients with COPD , 2012, PloS one.

[17]  L. V. van Loon,et al.  A single bout of exercise activates skeletal muscle satellite cells during subsequent overnight recovery , 2012, Experimental physiology.

[18]  S. Powers,et al.  Oxidative stress and disuse muscle atrophy: cause or consequence? , 2012, Current opinion in clinical nutrition and metabolic care.

[19]  L. V. van Loon,et al.  Leucine induces myofibrillar protein accretion in cultured skeletal muscle through mTOR dependent and -independent control of myosin heavy chain mRNA levels. , 2012, Molecular nutrition & food research.

[20]  M. Crow,et al.  A critical role for muscle ring finger-1 in acute lung injury-associated skeletal muscle wasting. , 2012, American journal of respiratory and critical care medicine.

[21]  D. Sabatini,et al.  mTOR Signaling in Growth Control and Disease , 2012, Cell.

[22]  M. Polkey,et al.  p38 Mitogen-activated Protein Kinase is Not Activated in the Quadriceps of Patients with Stable Chronic Obstructive Pulmonary Disease , 2012, COPD.

[23]  J. Roca,et al.  Does oxidative stress modulate limb muscle atrophy in severe COPD patients? , 2012, European Respiratory Journal.

[24]  M. Polkey,et al.  Quadriceps wasting and physical inactivity in patients with COPD , 2012, European Respiratory Journal.

[25]  I. Seiliez,et al.  Leucine limitation regulates myf5 and myoD expression and inhibits myoblast differentiation. , 2012, Experimental cell research.

[26]  B. M. Murali Mohan,et al.  Systemic manifestations of COPD. , 2012, The Journal of the Association of Physicians of India.

[27]  R. Chen,et al.  Serum myostatin levels and skeletal muscle wasting in chronic obstructive pulmonary disease. , 2012, Respiratory medicine.

[28]  Shakir Ali,et al.  Chronic hypobaric hypoxia mediated skeletal muscle atrophy: role of ubiquitin–proteasome pathway and calpains , 2012, Molecular and Cellular Biochemistry.

[29]  J. Riley,et al.  Metabolic profiling detects biomarkers of protein degradation in COPD patients , 2011, European Respiratory Journal.

[30]  V. Baracos,et al.  Central nervous system inflammation induces muscle atrophy via activation of the hypothalamic–pituitary–adrenal axis , 2011, The Journal of experimental medicine.

[31]  M. Kelders,et al.  Glycogen synthase kinase-3β is required for the induction of skeletal muscle atrophy. , 2011, American journal of physiology. Cell physiology.

[32]  A. Yodh,et al.  O2 Regulates Skeletal Muscle Progenitor Differentiation through Phosphatidylinositol 3-Kinase/AKT Signaling , 2011, Molecular and Cellular Biology.

[33]  M. Polkey,et al.  Downregulation of the serum response factor/miR-1 axis in the quadriceps of patients with COPD , 2011, Thorax.

[34]  N. Hanania,et al.  Resting energy expenditure and protein turnover are increased in patients with severe chronic obstructive pulmonary disease. , 2011, Metabolism: clinical and experimental.

[35]  I. Simpson,et al.  REDD1 (regulated in development and DNA damage response 1) expression in skeletal muscle as a surrogate biomarker of the efficiency of glucocorticoid receptor blockade. , 2011, Biochemical and biophysical research communications.

[36]  E. Barreiro,et al.  Inflammatory cells and apoptosis in respiratory and limb muscles of patients with COPD. , 2011, Journal of applied physiology.

[37]  Josep Roca,et al.  A Systems Biology Approach Identifies Molecular Networks Defining Skeletal Muscle Abnormalities in Chronic Obstructive Pulmonary Disease , 2011, PLoS Comput. Biol..

[38]  T. Zimmers,et al.  STAT3 Activation in Skeletal Muscle Links Muscle Wasting and the Acute Phase Response in Cancer Cachexia , 2011, PloS one.

[39]  S. Muro,et al.  Impact of exacerbations on emphysema progression in chronic obstructive pulmonary disease. , 2011, American journal of respiratory and critical care medicine.

[40]  Christopher S. Stevenson,et al.  Moving towards a new generation of animal models for asthma and COPD with improved clinical relevance. , 2011, Pharmacology & therapeutics.

[41]  P. Gluckman,et al.  Human myostatin negatively regulates human myoblast growth and differentiation. , 2011, American journal of physiology. Cell physiology.

[42]  J. Lammers,et al.  Level of daily physical activity in individuals with COPD compared with healthy controls , 2011, Respiratory research.

[43]  Keiichi Fukuda,et al.  Crosstalk between glucocorticoid receptor and nutritional sensor mTOR in skeletal muscle. , 2011, Cell metabolism.

[44]  E. Mercken,et al.  Decreased exercise-induced expression of nuclear factor-κB-regulated genes in muscle of patients with COPD. , 2011, Chest.

[45]  D. Allen,et al.  Myostatin up-regulation is associated with the skeletal muscle response to hypoxic stimuli , 2011, Molecular and Cellular Endocrinology.

[46]  S. Kandarian,et al.  Identification of Genes that Elicit Disuse Muscle Atrophy via the Transcription Factors p50 and Bcl-3 , 2011, PloS one.

[47]  Alexander Doyle,et al.  Toll‐like receptor 4 mediates lipopolysaccharide‐induced muscle catabolism via coordinate activation of ubiquitin‐proteasome and autophagy‐lysosome pathways , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[48]  C. Reggiani,et al.  Cellular and molecular responses of human skeletal muscle exposed to hypoxic environment. , 2011, Journal of biological regulators and homeostatic agents.

[49]  W. Bauman,et al.  Protection against dexamethasone-induced muscle atrophy is related to modulation by testosterone of FOXO1 and PGC-1α. , 2010, Biochemical and biophysical research communications.

[50]  M. Polkey,et al.  Quadriceps myostatin expression in COPD , 2010, European Respiratory Journal.

[51]  Y. Rong,et al.  TLR4 Activation Is Required for IL-17–Induced Multiple Tissue Inflammation and Wasting in Mice , 2010, The Journal of Immunology.

[52]  S. Zakynthinos,et al.  Effect of pulmonary rehabilitation on muscle remodelling in cachectic patients with COPD , 2010, European Respiratory Journal.

[53]  F. Costes,et al.  Downregulation of Akt/mammalian target of rapamycin pathway in skeletal muscle is associated with increased REDD1 expression in response to chronic hypoxia. , 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

[54]  M. Decramer,et al.  Resistance training prevents deterioration in quadriceps muscle function during acute exacerbations of chronic obstructive pulmonary disease. , 2010, American journal of respiratory and critical care medicine.

[55]  P. Greenhaff,et al.  Physiological control of muscle mass in humans during resistance exercise, disuse and rehabilitation , 2010, Current opinion in clinical nutrition and metabolic care.

[56]  S. McGee,et al.  AMPK-mediated regulation of transcription in skeletal muscle. , 2010, Clinical science.

[57]  D. Brooks,et al.  Cellular markers of muscle atrophy in chronic obstructive pulmonary disease. , 2010, American journal of respiratory cell and molecular biology.

[58]  D. Accili,et al.  Hypoxia converts the myogenic action of insulin-like growth factors into mitogenic action by differentially regulating multiple signaling pathways , 2010, Proceedings of the National Academy of Sciences.

[59]  M. Tarnopolsky,et al.  Little change in markers of protein breakdown and oxidative stress in humans in immobilization-induced skeletal muscle atrophy. , 2010, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

[60]  M. Decramer,et al.  Gene Expression Profiling in Vastus Lateralis Muscle During an Acute Exacerbation of COPD , 2010, Cellular Physiology and Biochemistry.

[61]  K. Tang,et al.  TNF‐α‐mediated reduction in PGC‐1α may impair skeletal muscle function after cigarette smoke exposure , 2010, Journal of cellular physiology.

[62]  F. Maltais,et al.  Ubiquitination and proteolysis in limb and respiratory muscles of patients with chronic obstructive pulmonary disease. , 2010, Proceedings of the American Thoracic Society.

[63]  S. M. Senf,et al.  Ros‐mediated activation of NF‐κB and Foxo during muscle disuse , 2010, Muscle & nerve.

[64]  S. M. Senf,et al.  FOXO signaling is required for disuse muscle atrophy and is directly regulated by Hsp70. , 2010, American journal of physiology. Cell physiology.

[65]  F. Kadi,et al.  Physical performance and muscular characteristics in different stages of COPD , 2009, Scandinavian journal of medicine & science in sports.

[66]  Amie J. Dirks-Naylor,et al.  Glucocorticoid-induced apoptosis and cellular mechanisms of myopathy , 2009, The Journal of Steroid Biochemistry and Molecular Biology.

[67]  W. Mitch,et al.  Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice. , 2009, The Journal of clinical investigation.

[68]  M. Polkey,et al.  Exercise and muscle dysfunction in COPD: implications for pulmonary rehabilitation. , 2009, Clinical science.

[69]  F. Maltais,et al.  Comparative assessment of the quadriceps and the diaphragm in patients with COPD. , 2009, Journal of applied physiology.

[70]  A. Hubbard,et al.  Limb Immobilization Induces a Coordinate Down-Regulation of Mitochondrial and Other Metabolic Pathways in Men and Women , 2009, PloS one.

[71]  S. Hatakeyama,et al.  Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size. , 2009, American journal of physiology. Cell physiology.

[72]  P. J. Barnes,et al.  Systemic manifestations and comorbidities of COPD , 2009, European Respiratory Journal.

[73]  B. Wouters,et al.  Regulation of autophagy through multiple independent hypoxic signaling pathways. , 2009, Current molecular medicine.

[74]  P. Bakakos,et al.  Plasma leptin and insulin-like growth factor I levels during acute exacerbations of chronic obstructive pulmonary disease , 2009, BMC pulmonary medicine.

[75]  K. Piehl-Aulin,et al.  Increased Serum Inflammatory Markers in the Absence of Clinical and Skeletal Muscle Inflammation in Patients with Chronic Obstructive Pulmonary Disease , 2009, Respiration.

[76]  Jeffrey S. Damrauer,et al.  The IκB kinases IKKα and IKKβ are necessary and sufficient for skeletal muscle atrophy , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[77]  D. Hittel,et al.  Increased Secretion and Expression of Myostatin in Skeletal Muscle From Extremely Obese Women , 2009, Diabetes.

[78]  G. Joos,et al.  Extrapulmonary manifestations of chronic obstructive pulmonary disease in a mouse model of chronic cigarette smoke exposure. , 2009, American journal of respiratory cell and molecular biology.

[79]  L. V. van Loon,et al.  Resistance exercise increases postprandial muscle protein synthesis in humans. , 2009, Medicine and science in sports and exercise.

[80]  B. Saltin,et al.  Skeletal muscle adaptations to prolonged exposure to extreme altitude: a role of physical activity? , 2008, High altitude medicine & biology.

[81]  B. Wouters,et al.  Hypoxia signalling through mTOR and the unfolded protein response in cancer , 2008, Nature Reviews Cancer.

[82]  M. Decramer,et al.  A 4-year trial of tiotropium in chronic obstructive pulmonary disease. , 2008, The New England journal of medicine.

[83]  S. Bodine,et al.  The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene. , 2008, American journal of physiology. Endocrinology and metabolism.

[84]  M. Decramer.  Pulmonary rehabilitation 2007: from bench to practice and back. , 2008, Clinical and investigative medicine. Medecine clinique et experimentale.

[85]  P. Tesch,et al.  Skeletal muscle proteolysis in response to short-term unloading in humans. , 2008, Journal of applied physiology.

[86]  L. Bertrand,et al.  Role of Akt/GSK-3beta/beta-catenin transduction pathway in the muscle anti-atrophy action of insulin-like growth factor-I in glucocorticoid-treated rats. , 2008, Endocrinology.

[87]  J. C. McDermott,et al.  Transforming growth factor-β and myostatin signaling in skeletal muscle , 2008 .

[88]  G. Joos,et al.  TNFα receptor genotype influences smoking-induced muscle-fibre-type shift and atrophy in mice , 2008, Acta Neuropathologica.

[89]  Marquette Method,et al.  EFFICACY OF THE , 2008 .

[90]  J. C. McDermott,et al.  Transforming growth factor-beta and myostatin signaling in skeletal muscle. , 2008, Journal of applied physiology.

[91]  R. Casaburi,et al.  Skeletal muscle adaptations to testosterone and resistance training in men with COPD. , 2007, Journal of applied physiology.

[92]  M. Decramer,et al.  Markers of inflammation and disuse in vastus lateralis of chronic obstructive pulmonary disease patients , 2007, European journal of clinical investigation.

[93]  A. Russell,et al.  Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease. , 2007, American journal of respiratory and critical care medicine.

[94]  Ji-zeng Du,et al.  Effects of hypoxia on glucose, insulin, glucagon, and modulation by corticotropin-releasing factor receptor type 1 in the rat. , 2007, Endocrinology.

[95]  S. Zakynthinos,et al.  Effects of rehabilitative exercise on peripheral muscle TNF&agr;, IL-6, IGF-I and MyoD expression in patients with COPD , 2007, Thorax.

[96]  C. Dogra,et al.  TNF‐related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle‐wasting cytokine , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[97]  M. Polkey,et al.  A prospective study of decline in fat free mass and skeletal muscle strength in chronic obstructive pulmonary disease , 2007, Respiratory research.

[98]  S. Kandarian,et al.  The FASEB Journal • Research Communication The ubiquitin-protein ligase Nedd4 targets Notch1 in , 2022 .

[99]  D. Attaix,et al.  Myostatin Gene Deletion Prevents Glucocorticoid- Induced Muscle Atrophy , 2022 .

[100]  Emiel F M Wouters,et al.  Systemic inflammation in chronic obstructive pulmonary disease: the role of exacerbations. , 2007, Proceedings of the American Thoracic Society.

[101]  J. Lammers,et al.  Expression of priming-associated cellular markers on neutrophils during an exacerbation of COPD. , 2006, Respiratory medicine.

[102]  J. Viña,et al.  Exercise-induced systemic effects in muscle-wasted patients with COPD. , 2006, Medicine and science in sports and exercise.

[103]  P. Razeghi,et al.  Atrophy, hypertrophy, and hypoxemia induce transcriptional regulators of the ubiquitin proteasome system in the rat heart. , 2006, Biochemical and biophysical research communications.

[104]  E. Wouters,et al.  Greater whole-body myofibrillar protein breakdown in cachectic patients with chronic obstructive pulmonary disease. , 2006, The American journal of clinical nutrition.

[105]  Thierry Troosters,et al.  Physical activity and hospitalization for exacerbation of COPD. , 2006, Chest.

[106]  Russell G. Jones,et al.  Hypoxia-induced energy stress regulates mRNA translation and cell growth. , 2006, Molecular cell.

[107]  B. Nordestgaard,et al.  Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: findings from the Copenhagen City Heart Study. , 2006, American journal of respiratory and critical care medicine.

[108]  E. Wouters,et al.  Muscle wasting and impaired muscle regeneration in a murine model of chronic pulmonary inflammation. , 2006, American journal of respiratory cell and molecular biology.

[109]  D. Glass,et al.  Skeletal muscle hypertrophy and atrophy signaling pathways. , 2005, The international journal of biochemistry & cell biology.

[110]  D. Herndon,et al.  Post burn muscle wasting and the effects of treatments. , 2005, The international journal of biochemistry & cell biology.

[111]  M. Martínez-García,et al.  Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease , 2005, Thorax.

[112]  E. Wouters,et al.  Body composition and mortality in chronic obstructive pulmonary disease. , 2005, The American journal of clinical nutrition.

[113]  D. Williamson,et al.  Acute treatment with TNF-alpha attenuates insulin-stimulated protein synthesis in cultures of C2C12 myotubes through a MEK1-sensitive mechanism. , 2005, American journal of physiology. Endocrinology and metabolism.

[114]  J. Lammers,et al.  Systemic inflammation in COPD visualised by gene profiling in peripheral blood neutrophils , 2005, Thorax.

[115]  J. Ketelslegers,et al.  Insulin-like growth factor-I gene transfer by electroporation prevents skeletal muscle atrophy in glucocorticoid-treated rats. , 2005, Endocrinology.

[116]  John R Hurst,et al.  Exacerbations and time spent outdoors in chronic obstructive pulmonary disease. , 2005, American journal of respiratory and critical care medicine.

[117]  N. Rosenthal,et al.  Reconciling data from transgenic mice that overexpress IGF-I specifically in skeletal muscle. , 2005, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[118]  J. Qin,et al.  Cloning and sequence analysis of myostatin promoter in sheep , 2005, DNA sequence : the journal of DNA sequencing and mapping.

[119]  W. Frontera,et al.  IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice , 2004, Cell.

[120]  R. Casaburi,et al.  Effects of testosterone and resistance training in men with chronic obstructive pulmonary disease. , 2004, American journal of respiratory and critical care medicine.

[121]  Simon W. Jones,et al.  Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[122]  G. Yancopoulos,et al.  The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. , 2004, Molecular cell.

[123]  M. Delp,et al.  Differential effects of emphysema on skeletal muscle fibre atrophy in hamsters , 2004, European Respiratory Journal.

[124]  Marco Sandri,et al.  Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy , 2004, Cell.

[125]  M. Capogrossi,et al.  Hypoxia Inhibits Myogenic Differentiation through Accelerated MyoD Degradation* , 2004, Journal of Biological Chemistry.

[126]  E. Wouters,et al.  Tumor necrosis factor‐alpha inhibits myogenic differentiation through MyoD protein destabilization , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[127]  V. Saks,et al.  Bcl-2/Bax protein expression in heart, slow-twitch and fast-twitch muscles in young rats growing under chronic hypoxia conditions , 2001, Molecular and Cellular Biochemistry.

[128]  W. Frontera,et al.  IKKbeta/NF-kappaB activation causes severe muscle wasting in mice. , 2004, Cell.

[129]  E. Wouters,et al.  Myopathological features in skeletal muscle of patients with chronic obstructive pulmonary disease , 2003, European Respiratory Journal.

[130]  F. Maltais,et al.  Catabolic/anabolic balance and muscle wasting in patients with COPD. , 2003, Chest.

[131]  J. Oldham,et al.  Prolonged underfeeding of sheep increases myostatin and myogenic regulatory factor Myf-5 in skeletal muscle while IGF-I and myogenin are repressed. , 2003, The Journal of endocrinology.

[132]  E. Wouters,et al.  Efficacy of nutritional supplementation therapy in depleted patients with chronic obstructive pulmonary disease. , 2003, Nutrition.

[133]  N. Chavannes,et al.  Local and systemic inflammation in patients with chronic obstructive pulmonary disease: soluble tumor necrosis factor receptors are increased in sputum. , 2002, American journal of respiratory and critical care medicine.

[134]  X. Busquets,et al.  Skeletal muscle apoptosis and weight loss in chronic obstructive pulmonary disease. , 2002, American journal of respiratory and critical care medicine.

[135]  H. van Mameren,et al.  Muscle fiber type IIX atrophy is involved in the loss of fat-free mass in chronic obstructive pulmonary disease. , 2002, The American journal of clinical nutrition.

[136]  D. Brooks,et al.  Nutritional supplementation for stable chronic obstructive pulmonary disease. , 2002, The Cochrane database of systematic reviews.

[137]  C. Rommel,et al.  Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways , 2001, Nature Cell Biology.

[138]  D J Glass,et al.  Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy , 2001, Science.

[139]  A. Ionescu,et al.  Inflammatory response and body composition in chronic obstructive pulmonary disease. , 2001, American journal of respiratory and critical care medicine.

[140]  M. Yamaki,et al.  A novel pathophysiologic phenomenon in cachexic patients with chronic obstructive pulmonary disease: the relationship between the circadian rhythm of circulating leptin and the very low-frequency component of heart rate variability. , 2001, American journal of respiratory and critical care medicine.

[141]  E. Wouters,et al.  Dose dependent increased mortality risk in COPD patients treated with oral glucocorticoids. , 2001, The European respiratory journal.

[142]  E. Wouters,et al.  Factors contributing to alterations in skeletal muscle and plasma amino acid profiles in patients with chronic obstructive pulmonary disease. , 2000, The American journal of clinical nutrition.

[143]  Yi-Ping Li,et al.  NF-κB mediates the protein loss induced by TNF-α in differentiated skeletal muscle myotubes , 2000 .

[144]  O. Shah,et al.  4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle. , 2000, American journal of physiology. Endocrinology and metabolism.

[145]  F. Maltais,et al.  Oxidative enzyme activities of the vastus lateralis muscle and the functional status in patients with COPD , 2000, Thorax.

[146]  C. Y. Wang,et al.  NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia. , 2000, Science.

[147]  A. Goris,et al.  Tissue depletion and health related quality of life in patients with chronic obstructive pulmonary disease. , 2000, Respiratory medicine.

[148]  H. Saito,et al.  The Relationship between Chronic Hypoxemia and Activation of the Tumor Necrosis Factor- α System in Patients with Chronic Obstructive Pulmonary Disease , 2000 .

[149]  Y. Li,et al.  NF-kappaB mediates the protein loss induced by TNF-alpha in differentiated skeletal muscle myotubes. , 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

[150]  E. Wouters,et al.  Disturbances in leptin metabolism are related to energy imbalance during acute exacerbations of chronic obstructive pulmonary disease. , 2000, American journal of respiratory and critical care medicine.

[151]  H. Saito,et al.  The relationship between chronic hypoxemia and activation of the tumor necrosis factor-alpha system in patients with chronic obstructive pulmonary disease. , 2000, American journal of respiratory and critical care medicine.

[152]  E. Wouters,et al.  Enhanced levels of whole-body protein turnover in patients with chronic obstructive pulmonary disease. , 2000, American journal of respiratory and critical care medicine.

[153]  E. Wouters,et al.  Characterization of nonresponse to high caloric oral nutritional therapy in depleted patients with chronic obstructive pulmonary disease. , 2000, American journal of respiratory and critical care medicine.

[154]  V. Edgerton,et al.  Myonuclear domains in muscle adaptation and disease , 1999, Muscle & nerve.

[155]  E. Wouters,et al.  Different patterns of chronic tissue wasting among patients with chronic obstructive pulmonary disease. , 1999, Clinical nutrition.

[156]  M. Westerterp-Plantenga,et al.  Appetite at "high altitude" [Operation Everest III (Comex-'97)]: a simulated ascent of Mount Everest. , 1999, Journal of applied physiology.

[157]  E. Wouters,et al.  Plasma leptin is related to proinflammatory status and dietary intake in patients with chronic obstructive pulmonary disease. , 1999, American journal of respiratory and critical care medicine.

[158]  F. Maltais,et al.  Peripheral muscle weakness in patients with chronic obstructive pulmonary disease. , 1998, American journal of respiratory and critical care medicine.

[159]  E. Wouters,et al.  Peak exercise response in relation to tissue depletion in patients with chronic obstructive pulmonary disease. , 1997, The European respiratory journal.

[160]  E. Wouters,et al.  Effects of an acute exacerbation on nutritional and metabolic profile of patients with COPD. , 1997, The European respiratory journal.

[161]  K. Westerterp,et al.  Total free living energy expenditure in patients with severe chronic obstructive pulmonary disease. , 1997, American journal of respiratory and critical care medicine.

[162]  M. Decramer,et al.  Functional and histologic picture of steroid-induced myopathy in chronic obstructive pulmonary disease. , 1996, American journal of respiratory and critical care medicine.

[163]  E. Wouters,et al.  Physiologic effects of nutritional support and anabolic steroids in patients with chronic obstructive pulmonary disease. A placebo-controlled randomized trial. , 1995, American journal of respiratory and critical care medicine.

[164]  J. Mege,et al.  Tumor necrosis factor-alpha levels and weight loss in chronic obstructive pulmonary disease. , 1994, American journal of respiratory and critical care medicine.

[165]  E. Wouters,et al.  Nutritional depletion in relation to respiratory and peripheral skeletal muscle function in out-patients with COPD. , 1994, The European respiratory journal.

[166]  J. Curtis,et al.  Emergent assessment and management of acute respiratory failure in COPD. , 1994, Clinics in chest medicine.

[167]  E. Wouters,et al.  Prevalence and characteristics of nutritional depletion in patients with stable COPD eligible for pulmonary rehabilitation. , 1993, The American review of respiratory disease.

[168]  A. Goldberg,et al.  Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting. , 1993, The American journal of physiology.

[169]  P A Tesch,et al.  Skeletal muscle responses to lower limb suspension in humans. , 1992, Journal of applied physiology.

[170]  J. Macdougall,et al.  Operation Everest II: structural adaptations in skeletal muscle in response to extreme simulated altitude. , 1991, Acta physiologica Scandinavica.

[171]  P. Cerretelli,et al.  II. Morphological Adaptations of Human Skeletal Muscle to Chronic Hypoxia* , 1990, International journal of sports medicine.

[172]  R. Edwards,et al.  Effects of clenbuterol and propranolol on muscle mass. Evidence that clenbuterol stimulates muscle beta-adrenoceptors to induce hypertrophy. , 1989, Biochemical Journal.

[173]  D. Geddes,et al.  Supplemental oxygen and exercise ability in chronic obstructive airways disease. , 1988, Thorax.

[174]  C. Scrimgeour,et al.  Muscle wasting in emphysema. , 1988, Clinical science.

[175]  K. Tracey,et al.  Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation , 1988, The Journal of experimental medicine.

[176]  H Raff,et al.  Renin-angiotensin II-aldosterone and ACTH-cortisol control during acute hypoxemia and exercise in patients with chronic obstructive pulmonary disease. , 1986, The American review of respiratory disease.

[177]  B. Lowell,et al.  Sites of protein conservation and loss during starvation: influence of adiposity. , 1984, The American journal of physiology.

[178]  L. Moldawer,et al.  Muscle proteolysis in sepsis or trauma. , 1983, The New England journal of medicine.