Alcohol consumption, blood pressure, lipids, and cardiovascular mortality.

Interest in the effects of alcohol on cardiovascular risk factors and disease has increased sharply with reports of complex and previously unsuspected associations. The present report focuses on the associations of alcohol with blood pressure, lipids, and cardiovascular disease mortality. The epidemiological evidence to date appears to support the idea that moderate alcohol consumption, defined as two drinks a day or less, may offer some protection for coronary heart disease, but that higher levels of alcohol promote hypertension and are directly toxic to the heart, leading to stroke, arrhythmias, cardiomyopathy, and perhaps even coronary heart disease.

[1]  M. Oliver Prevention of coronary heart disease--propaganda, promises, problems, and prospects. , 1986, Circulation.

[2]  R. Krauss,et al.  The effect of cessation and resumption of moderate alcohol intake on serum high-density-lipoprotein subfractions. A controlled study. , 1984, The New England journal of medicine.

[3]  E. Sainz,et al.  Reduction of blood pressure with calcium supplementation in young adults. , 1983, JAMA.

[4]  D. McCarron,et al.  Dietary calcium in human hypertension , 1982 .

[5]  R B Wallace,et al.  Alcohol consumption and blood pressure. The lipid research clinics prevalence study. , 1981, Hypertension.

[6]  A. Siegelaub,et al.  Alcohol and mortality. A ten-year Kaiser-Permanente experience. , 1981, Annals of internal medicine.

[7]  M. Marmot,et al.  ALCOHOL AND MORTALITY: A U-SHAPED CURVE , 1981, The Lancet.

[8]  S. Shapiro,et al.  Alcoholic beverages and myocardial infarction in young women. , 1981, American journal of public health.

[9]  R. Bawol,et al.  Epidemiology as a guide to clinical decisions. The association between triglyceride and coronary heart disease. , 1980, The New England journal of medicine.

[10]  T. Dawber,et al.  FREQUENCY OF ALCOHOL CONSUMPTION AND MORBIDITY AND MORTALITY: The Yugoslavia Cardiovascular Disease Study , 1980, The Lancet.

[11]  W. Willett,et al.  Effects of beer, wine, and liquor in coronary deaths. , 1979, JAMA.

[12]  R. Ylikahri,et al.  Renin, aldosterone and cortisol during ethanol intoxication and hangover. , 1979, Acta physiologica Scandinavica.

[13]  A. P. Haines,et al.  Characteristics affecting fibrinolytic activity and plasma fibrinogen concentrations. , 1979, British medical journal.

[14]  R. Ylikahri,et al.  Plasma vasopressin in ethanol intoxication and hangover. , 1978, Acta physiologica Scandinavica.

[15]  D. W. Goodwin Hereditary factors in alcoholism. , 1978, Hospital practice.

[16]  A. B. Weisse,et al.  Arrhythmias and the "Holiday Heart": alcohol-associated cardiac rhythm disorders. , 1978, American heart journal.

[17]  R. Scheig,et al.  Ethanol-induced hypertriglyceridemia. Prevalence and contributing factors. , 1978, The American journal of clinical nutrition.

[18]  Coffee, alcohol and risk of coronary heart disease among Japanese men living in Hawaii. , 1977, The New England journal of medicine.

[19]  W. Castelli,et al.  ALCOHOL AND BLOOD LIPIDS The Cooperative Lipoprotein Phenotyping Study , 1977, The Lancet.

[20]  A. Siegelaub,et al.  Alcohol consumption and blood pressure. Kaiser-Permanente Multiphasic Health Examination data. , 1977, The New England journal of medicine.

[21]  D. Thelle,et al.  THE TROMSØHEART-STUDY HIGH-DENSITY LIPOPROTEIN AND CORONARY HEART-DISEASE: A PROSPECTIVE CASE-CONTROL STUDY , 1977, The Lancet.

[22]  M C Hjortland,et al.  High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. , 1977, The American journal of medicine.

[23]  J. Vreeken,et al.  REBOUND THROMBOCYTOSIS AFTER ALCOHOL ABUSE: A POSSIBLE FACTOR IN THE PATHOGENESIS OF THROMBOEMBOLIC DISEASE , 1977, The Lancet.

[24]  W. Stason,et al.  Alcohol consumption and nonfatal myocardial infarction. , 1976, American journal of epidemiology.

[25]  Krawitt El Effect of ethanol ingestion on duodenal calcium transport. , 1975 .

[26]  A. Siegelaub,et al.  Alcohol consumption before myocardial infarction. Results from the Kaiser-Permanente epidemiologic study of myocardial infarction. , 1974 .

[27]  M. Haut,et al.  The effect of ethanol on hemostatic properties of human blood platelets. , 1974, The American journal of medicine.

[28]  J. Mendelson,et al.  Adrenal Function and Alcoholism: II. Catecholamines , 1971, Psychosomatic medicine.

[29]  C. Lieber,et al.  Hematologic effects of alcohol in man in the absence of nutritional deficiency. , 1969, The New England journal of medicine.

[30]  J. Häggendal,et al.  Arterial noradrenaline levels after ethanol withdrawal. , 1967, Lancet.

[31]  C. S. Alexander Idiopathic heart disease. I. Analysis of 100 cases, with special reference to chronic alcoholism. , 1966, The American journal of medicine.

[32]  P. Saville CHANGES IN BONE MASS WITH AGE AND ALCOHOLISM. , 1965, The Journal of bone and joint surgery. American volume.

[33]  H. Eder,et al.  Protein-lipid relationships in human plasma. II. In atherosclerosis and related conditions. , 1951, The American journal of medicine.