Using results of eye movement signal analysis in the neural network recognition of otoneurological patients

We extracted a collection of eye movement signals employed for almost two decades in clinical otoneurological tests at a balance laboratory. During those years we designed and programmed signal analysis methods to analyse their features in detail and to compute medically important attributes. In the present study, using such attributes and their results computed we classified test cases into groups of healthy subjects and patients with multilayer perceptron neural networks. Classification succeeded in total accuracies from 60% to 90% depending on the type of eye movements, which were saccades, nystagmus, sinusoidal movements and vestibulo-ocular reflex stimulated in two different ways; these are the chief eye movement tests applied in otoneurology.

[1]  Martti Juhola,et al.  A Signal Analysis Technique of Vestibulo-Ocular Reflex Stimulated with Impulsive Head Movements , 2006, Annals of Biomedical Engineering.

[2]  R. Carpenter,et al.  Movements of the Eyes , 1978 .

[3]  Dorian Pyle,et al.  Data Preparation for Data Mining , 1999 .

[4]  M Juhola,et al.  A syntactic analysis method for eye movements of vestibulo-ocular reflex. , 1995, Computer methods and programs in biomedicine.

[5]  H. Collewijn,et al.  Early components of the human vestibulo-ocular response to head rotation: latency and gain. , 2000, Journal of neurophysiology.

[6]  H. Collewijn,et al.  Velocity step responses of the human gaze pursuit system. Experiments with sigma-movement , 1985, Vision Research.

[7]  Ian H. Witten,et al.  Data mining: practical machine learning tools and techniques, 3rd Edition , 1999 .

[8]  D. O'leary,et al.  High-frequency autorotational testing of the vestibulo-ocular reflex. , 1990, Neurologic clinics.

[9]  H Collewijn,et al.  Gain and delay of human vestibulo-ocular reflexes to oscillation and steps of the head by a reactive torque helmet. I. Normal subjects. , 1997, Acta oto-laryngologica.

[10]  M. Juhola,et al.  Visual stimulator using laser beam for eye-movement studies , 2006, Medical and Biological Engineering and Computing.

[11]  Ian H. Witten,et al.  Data mining: practical machine learning tools and techniques with Java implementations , 2002, SGMD.

[12]  R. Baloh,et al.  The saccade velocity test , 1975, Neurology.

[13]  H Aalto,et al.  Motorized head impulse stimulator to determine angular horizontal vestibulo-ocular reflex , 2002, Journal of medical engineering & technology.

[14]  Martti Juhola.  A syntactic method for analysis of saccadic eye movements , 1986, Pattern Recognit..

[15]  M Juhola,et al.  On identification of saccades from sinusoidal eye movement signals. , 1992, International journal of bio-medical computing.

[16]  M Juhola.  Effects of digital filtering on the parameters of sinusoidal tracking eye movements. , 1995, Computers and biomedical research, an international journal.

[17]  H Aalto,et al.  A measurement system of head movements for the vestibulo-ocular reflex. , 1993, Medical progress through technology.

[18]  M Juhola.  A syntactic analysis method for sinusoidal tracking eye movements. , 1991, Computers and biomedical research, an international journal.

[19]  M Juhola.  A syntactic method for analysis of nystagmus and smooth pursuit eye movement. , 1988, Computer methods and programs in biomedicine.

[20]  H Collewijn,et al.  Gain and delay of human vestibulo-ocular reflexes to oscillation and steps of the head by a reactive torque helmet. II. Vestibular-deficient subjects. , 1997, Acta oto-laryngologica.

[21]  Terry A. Bahill,et al.  Variability and development of a normative data base for saccadic eye movements. , 1981, Investigative ophthalmology & visual science.

[22]  Martti Juhola,et al.  Effects of Digital Filtering on the Parameters of Impulse-Like Eye Movements , 2004, Journal of Clinical Monitoring and Computing.

[23]  Kevin Swingler,et al.  Applying neural networks - a practical guide , 1996 .

[24]  M Juhola,et al.  Median filtering is appropriate to signals of saccadic eye movements. , 1991, Computers in biology and medicine.

[25]  H Aalto,et al.  Computational problems in the analysis of eye movement signals in the determination of vestibulo-ocular reflex. , 1997, Computers and biomedical research, an international journal.