A study on visual evoked responses in childhood epilepsy with occipital paroxysms

As some apparently idiopatic epilepsies may occasionally pose diagnostic difficulties in regard to their precise status of etiology, evoked potentials, particularly visual evoked potential (VEP), may contribute to the diagnosis of childhood epilepsy with occipital paroxysms (CEOP) as a subsidiary method of evaluation. This study includes 19 children (10 boys 52.6%; 9 girls 47.4%) ranging in age from 5 to 17 years (mean SD = 9.68 3.28) suffering from CEOP and a control group of 30 normal children, matched for chronological age and sex. Peak amplitudes and latencies of the P100 component for pattern-shift VEP (PVEP) and of major positivity for flash VEP (FVEP) are measured, respectively. The results from this study demonstrate that amplitude and latency values in patients with CEOP differs insignificantly when compared with controls. Although, non-significantly, mean values of amplitudes for both PVEP and FVEP were higher in the patients than in the normal children, whereas latencies in FVEP were somewhat longer. There may be some tendency for the amplitudes to increase and the latencies to be delayed in VEPs in patients with CEOP, when an overall interpretation of our and similar studies are considered. In certain cases of diagnostic difficulty, VEP values may provide further information for the clinician, regarding either a symptomatic or an idiopathic nature of the underlying disorder.

[1]  E. Hoppe-Hirsch.  Occipital seizures and epilepsies in children , 1994, Child's Nervous System.

[2]  F. Sartucci,et al.  Cortical reflex myoclonus in rett syndrome , 1998, Annals of neurology.

[3]  G. Capizzi,et al.  Early‐Onset Benign Occipital Seizure Susceptibility Syndrome , 1997, Epilepsia.

[4]  G. Farnarier.  Potentiels évoqués en épileptologie , 1996 .

[5]  A. Dirican,et al.  Effect of valproate and carbamazepine on visual evoked potentials in epileptic children , 1995, Acta paediatrica Japonica : Overseas edition.

[6]  J HernándezGallego,et al.  Migraine and epilepsy , 1995 .

[7]  M. Brinciotti.  Effects of chronic high serum levels of phenobarbital on evoked potentials in epileptic children. , 1994, Electroencephalography and clinical neurophysiology.

[8]  F. Andermann.  Occipital Seizures And Epilepsies in Children , 1993 .

[9]  C. Panayiotopoulos.  Benign childhood epilepsy with occipital paroxysms , 1993 .

[10]  T. Halonen,et al.  γ‐Vinyl GABA (Vigabatrin) in Epilepsy: Clinical, Neurochemical, and Neurophysiologic Monitoring in Epileptic Patients , 1992, Epilepsia.

[11]  B. Bernardina,et al.  Idiopathic partial epilepsies in children , 1992 .

[12]  H. Gastaut.  Benign epilepsy of childhood with occipital paroxysms , 1992 .

[13]  A. Beaumanoir,et al.  Benign epilepsy of childhood with occipital paroxysms. , 1992, Epilepsy research. Supplement.

[14]  E. Rodin,et al.  Epilepsy, sleep, and sleep deprivation , 1991 .

[15]  B. dalla Bernardina,et al.  Sleep and benign partial epilepsies of childhood: EEG and evoked potentials study. , 1991, Epilepsy research. Supplement.

[16]  J. Aicardi,et al.  Benign Nocturnal Childhood Occipital Epilepsy: A New Syndrome with Nocturnal Seizures, Tonic Deviation of the Eyes, and Vomiting , 1989, Journal of child neurology.

[17]  R. Mattson,et al.  Proposal for revised classification of epilepsies and epileptic syndromes. Commission on Classification and Terminology of the International League Against Epilepsy. , 1989, Epilepsia.

[18]  J. Mancini,et al.  Etude des potentiels evoques multimodalitaires dans les epilepsies partielles de l'enfant , 1988, Neurophysiologie Clinique/Clinical Neurophysiology.

[19]  J. Hockaday,et al.  Migraine and epilepsy , 1988 .

[20]  P. Despland,et al.  Partial Epilepsy in Neurologically Normal Children: Clinical Syndromes and Prognosis , 1986, Epilepsia.

[21]  M. Penttilä,et al.  Pattern‐Reversal VEP and Cortical SEP Latency Prolongations in Epilepsy , 1985, Epilepsia.

[22]  S. Tobimatsu,et al.  Pathogenesis of giant somatosensory evoked potentials in progressive myoclonic epilepsy. , 1985, Brain : a journal of neurology.

[23]  M. Penttilä,et al.  Prolonged cortical somatosensory evoked potential latencies in progressive myoclonus epilepsy , 1984, Journal of the Neurological Sciences.

[24]  E. Faught,et al.  Pattern-reversal visual evoked potentials in photosensitive epilepsy. , 1984, Electroencephalography and clinical neurophysiology.

[25]  J. Aicardi,et al.  Clinical findings in children with occipital spike‐wave complexes suppressed by eye‐opening , 1983, Neurology.

[26]  S. Chayasirisobhon,et al.  Brainstem Auditory Evoked Potential Recording in Patients with Epilepsy , 1982, Clinical EEG.

[27]  M. Hallett,et al.  Cortical reflex myoclonus , 1979, Neurology.

[28]  G. Harding,et al.  A Controlled Study of the Effect of Sodium Valproate on Photosensitive Epilepsy and Its Prognosis , 1978, Epilepsia.

[29]  O. Creutzfeldt,et al.  Visual evoked potentials of patients with epilepsy and of a control group. , 1970, Electroencephalography and clinical neurophysiology.