Neurobehavioral aspects of affective disorders.

A PSYCHOLOGICAL PERS PECTIVE ON THE NEUROBIOLOGY OF AFFECTIVE DISORDERS . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . 457 DOPAMINE FUNCTIONING, BEHAVIORAL FACILITATION, AND B I POLAR AFFECTIVE DISORDERS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . 458 The Behavioral Facilitation System . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 458 Neurobiology of the Behavioral Facilitation System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462 Implications for Bipolar Affective Disorders . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . 471 BRAIN IMAGING AND THE MAJOR AFFECTIVE DISORDERS. . . . . . . . . . . . . . . . . . . . . . . 476 Overview of Imaging Techniques . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477 CT Scan Studies. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 481 PET and MRI Studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . 484 Conclusion . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 486 FINAL REMARKS . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . 487

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