Current treatment of cerebral metastasis

Brain metastasis from systemic cancer remains a significant source of morbidity and mortality. Current treatment modalities include surgery, whole brain radiation, radiosurgery, brachytherapy, chemotherapy, and other experimental methods such as hyperthermia, hormonal therapy, and the use of biological modifiers. In this article we review and evaluate recent developments in these treatment modalities for the management of cerebral metastasis.