The neurons in the primate subthalamic nucleus: A Golgi and electron microscopic study

In Golgi preparations of the adult monkey(Macaca mulatta) local interneurons and two varieties of principal neurons, radiating and elongated fusiform, are found in the subthalamic nucleus. The cell bodies of the radiating neurons have a few delicate, somatic spines some of which are occasionally bilobed and trilobed. Five to eight dendritic trunks give rise to branching, tapering dendrites, which may extend for over 400 microns. These dendrites are much thinner than the dendrites in the globus pallidus and the substantia nigra. Some neurons have many and some neurons have few dendritic spines. When numerous the dendritic spines are concentrated on the dendritic trunks and proximal dendrites. The relatively few elongated fusiform neurons are found not only in the capsule but also in the center of the nucleus. Most dendrites emerge from the opposite poles of their smooth surfaced cell bodies. They have a few dendritic spines. Some of these dendrites extend for more than 750 microns.

[1]  C. Fox,et al.  Zinc chromate modification of the Golgi technic. , 1951, Stain technology.

[2]  U Karlsson,et al.  Three-dimensional studies of neurons in the lateral geniculate nucleus of the rat. I. Organelle organization in the perikaryon and its proximal branches. , 1966, Journal of ultrastructure research.

[3]  T. To¨mbo¨l.  Short neurons and their synaptic relations in the specific thalamic nuclei. , 1967 .

[4]  M. Carpenter,et al.  Efferent fibers of the subthalamic nucleus in the monkey. A comparison of the efferent projections of the subthalamic nucleus, substantia nigra and globus pallidus. , 1967, The American journal of anatomy.

[5]  S L Palay,et al.  THE FINE STRUCTURE OF THE LATERAL VESTIBULAR NUCLEUS IN THE RAT : I. Neurons and Neuroglial Cells. , 1968, The Journal of cell biology.

[6]  H. Ralston,et al.  The fine structure of neurons and synapses in the ventrobasal thalamus of the cat , 1969 .

[7]  E. V. Famiglietti,et al.  Dendro-dendritic synapses in the lateral geniculate nucleus of the cat. , 1970, Brain research.

[8]  T. Frigyesi,et al.  Basal ganglia-diencephalon synaptic relations in the cat. 3. An intracellular study of ansa lenticularis, lenticular fasciculus and pallidosubthalamic projection activities. , 1971, Brain research.

[9]  H. Ralston.  Evidence for Presynaptic Dendrites and a Proposal for their Mechanism of Action , 1971, Nature.

[10]  R L Schultz,et al.  Intranuclear inclusions in neurons of the cat primary olfactory system. , 1971, Brain research.

[11]  B. N. Harding.  Dendro-dendritic synapses, including reciprocal synapses, in the ventrolateral nucleus of the monkey thalamus. , 1971, Brain research.

[12]  A. Lieberman,et al.  Presynaptic dendrites and a distinctive class of synaptic vesicle in the rat dorsal lateral geniculate nucleus. , 1972, Brain research.

[13]  T. Tsubokawa,et al.  Pallidal and tegmental inhibition of oscillatory slow waves and unit activity in the subthalamic nucleus. , 1972, Brain research.

[14]  A. Scheibel,et al.  On dendrodendritic relations in the dorsal thalamus of the adult cat. , 1972, Experimental neurology.

[15]  B. N. Harding.  An ultrastructural study of the centre median and ventrolateral thalamic nuclei of the monkey. , 1973, Brain research.

[16]  A. Lieberman.  Neurons with presynaptic perikarya and presynaptic dendrites in the rat lateral geniculate nucleus. , 1973, Brain research.

[17]  B. N. Harding,et al.  An ultrastructural study of the termination of afferent fibres within the ventrolateral and centre median nuclei of the monkey thalamus. , 1973, Brain research.

[18]  H J Nauta,et al.  Efferent projections of the subthalamic nucleus. , 1974, Transactions of the American Neurological Association.

[19]  A. Lieberman,et al.  Aspects of the synaptic organization of intrinsic neurons in the dorsal lateral geniculate nucleus , 1974, Journal of neurocytology.

[20]  J Szentágothai,et al.  Triadic synaptic arrangements and their possible significance in the lateral geniculate nucleus of the monkey. , 1974, Brain research.