Environmental Health Sciences

EHS 500a or b, Independent Study in Environmental Health Sciences Nicole Deziel Independent study on a specific research topic agreed upon by both faculty and M.P.H. student. Research projects may be “dry” (i.e., statistical or epidemiologic analysis) or “wet” (i.e., laboratory analyses). The student meets with the EHS faculty member at the beginning of the term to discuss goals and expectations and to develop a syllabus. The student becomes familiar with the research models, approaches, and methods utilized by the faculty. The student is expected to spend at least ten hours per week working on their project and to produce a culminating paper at the end of the term.

[1]  Hyunju Kim,et al.  The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring , 2016, Science.

[2]  A. Saghatelian,et al.  Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity. , 2012, Genes & development.

[3]  M. Surani,et al.  Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity , 2016, Cell.

[4]  F. Servant,et al.  The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORγt and Controls Metabolic Disease. , 2015, Cell metabolism.

[5]  D. Hyde,et al.  Ozone-induced airway epithelial cell death, the neurokinin-1 receptor pathway, and the postnatal developing lung. , 2014, American journal of physiology. Lung cellular and molecular physiology.

[6]  G. Chrousos,et al.  Stress Response and Child Health , 2012, Science Signaling.

[7]  M. Blaser,et al.  Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences , 2014, Cell.

[8]  D. Dombrowicz,et al.  The impact of diet on asthma and allergic diseases , 2015, Nature Reviews Immunology.

[9]  V. Tremaroli,et al.  Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life. , 2015, Cell host & microbe.

[10]  C. Lowry,et al.  Hygiene and other early childhood influences on the subsequent function of the immune system , 2012, Brain Research.

[11]  Guoping Feng,et al.  Adult Restoration of Shank3 Expression Rescues Selective Autistic-Like Phenotypes , 2016, Nature.

[12]  G. Fishell,et al.  Lactobacillus plantarum strain maintains growth of infant mice during chronic undernutrition , 2016 .

[13]  A. Garfield,et al.  Developmental Programming Mediated by Complementary Roles of Imprinted Grb10 in Mother and Pup , 2014, PLoS biology.

[14]  M. Inouye,et al.  The Infant Nasopharyngeal Microbiome Impacts Severity of Lower Respiratory Infection and Risk of Asthma Development , 2015, Cell Host & Microbe.

[15]  T. McDade.  Early environments and the ecology of inflammation , 2012, Proceedings of the National Academy of Sciences.

[16]  Xiaoping Zhou,et al.  Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation. , 2015, Molecular cell.

[17]  Feng Zhang,et al.  Enhancer Activation Requires trans-Recruitment of a Mega Transcription Factor Complex , 2014, Cell.

[18]  K. McCoy,et al.  Intestinal Microbial Diversity during Early-Life Colonization Shapes Long-Term IgE Levels , 2013, Cell host & microbe.

[19]  Yunfu Lin,et al.  Environmental stress induces trinucleotide repeat mutagenesis in human cells , 2015, Proceedings of the National Academy of Sciences.

[20]  Jim van Os,et al.  The environment and schizophrenia , 2010, Nature.

[21]  Michael J. Barratt,et al.  Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children , 2016, Science.

[22]  U. Sauer,et al.  The maternal microbiota drives early postnatal innate immune development , 2016, Science.

[23]  Elisabeth B. Binder,et al.  Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment Interactions , 2015, Neuron.

[24]  C. Ballaré,et al.  Genome-wide activity of unliganded estrogen receptor-α in breast cancer cells , 2014, Proceedings of the National Academy of Sciences.

[25]  A. Keech,et al.  Multigenerational Undernutrition Increases Susceptibility to Obesity and Diabetes that Is Not Reversed after Dietary Recuperation. , 2015, Cell metabolism.

[26]  B. Schaub,et al.  Immune mechanisms and development of childhood asthma. , 2014, The Lancet. Respiratory medicine.

[27]  J. Gordon,et al.  Cultivating Healthy Growth and Nutrition through the Gut Microbiota , 2015, Cell.

[28]  B. Chipps,et al.  Association of Improved Air Quality With Lung Development in Children , 2015, Pediatrics.

[29]  M. Bhaskaran,et al.  Pleiotrophin Regulates Lung Epithelial Cell Proliferation and Differentiation during Fetal Lung Development via β-Catenin and Dlk1* , 2009, The Journal of Biological Chemistry.

[30]  C. Ohlsson,et al.  Maternal testosterone exposure increases anxiety-like behavior and impacts the limbic system in the offspring , 2015, Proceedings of the National Academy of Sciences.

[31]  S. Lynch,et al.  Microbiota in allergy and asthma and the emerging relationship with the gut microbiome. , 2015, Cell host & microbe.

[32]  T. Iguchi,et al.  Epithelial estrogen receptor 1 intrinsically mediates squamous differentiation in the mouse vagina , 2015, Proceedings of the National Academy of Sciences.

[33]  D. Pfaff,et al.  Stress and the dynamic genome: Steroids, epigenetics, and the transposome , 2014, Proceedings of the National Academy of Sciences.

[34]  Tobias Kollmann,et al.  Early infancy microbial and metabolic alterations affect risk of childhood asthma , 2015, Science Translational Medicine.

[35]  B. McEwen,et al.  Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress , 2015, Proceedings of the National Academy of Sciences.

[36]  Marcus E. Raichle,et al.  Feeding the brain and nurturing the mind: Linking nutrition and the gut microbiota to brain development , 2015, Proceedings of the National Academy of Sciences.

[37]  Philip J Landrigan,et al.  Children's health and the environment: an overview. , 2011, The Mount Sinai journal of medicine, New York.

[38]  Martha J. Farah,et al.  Socioeconomic status and the brain: mechanistic insights from human and animal research , 2010, Nature Reviews Neuroscience.

[39]  D. Notterman,et al.  Social disadvantage, genetic sensitivity, and children’s telomere length , 2014, Proceedings of the National Academy of Sciences.