UDCA and 18β-GA alleviate ethinylestradiol-induced cholestasis via downregulating RORγt and CXCR3 signaling pathway in iNKT cells.
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[1] Sihan Sheng,et al. Dihydroartemisinin-ursodeoxycholic acid conjugate is a potential treatment agent for inflammatory bowel disease. , 2023, International immunopharmacology.
[2] Luyong Zhang,et al. iNKT17 cells play a pathogenic role in ethinylestradiol-induced cholestatic hepatotoxicity , 2022, Archives of Toxicology.
[3] L. Tao,et al. Fluorofenidone ameliorates cholestasis and fibrosis by inhibiting hepatic Erk/-Egr-1 signaling and Tgfβ1/Smad pathway in mice. , 2022, Biochimica et biophysica acta. Molecular basis of disease.
[4] Xinzhi Wang,et al. Activation of natural killer T cells contributes to Th1 bias in the murine liver after 14 d of ethinylestradiol exposure , 2022, World journal of gastroenterology.
[5] Hetong Zhou,et al. IL‐17A produced by invariant natural killer T cells and CD3+CD56+αGalcer‐CD1d tetramer– T cells promote liver fibrosis in patients with primary biliary cholangitis , 2022, Journal of leukocyte biology.
[6] Daeui Park,et al. Trovafloxacin drives inflammation-associated drug-induced adverse hepatic reaction through changing macrophage polarization. , 2022, Toxicology in vitro : an international journal published in association with BIBRA.
[7] A. Edelman,et al. Contraception Selection, Effectiveness, and Adverse Effects: A Review. , 2021, JAMA.
[8] Jianxia Wen,et al. Comparative Evidence for Intrahepatic Cholestasis of Pregnancy Treatment With Traditional Chinese Medicine Therapy: A Network Meta-Analysis , 2021, Frontiers in Pharmacology.
[9] Jin-yu Yang,et al. The Pathological Mechanisms of Estrogen-Induced Cholestasis: Current Perspectives , 2021, Frontiers in Pharmacology.
[10] A. Theiss,et al. RORγt protein modifications and IL-17-mediated inflammation. , 2021, Trends in immunology.
[11] J. Hippisley-Cox,et al. Use of menopausal hormone therapy and risk of dementia: nested case-control studies using QResearch and CPRD databases , 2021, BMJ.
[12] T. Simoncini,et al. Hormone therapy in the postmenopausal years: considering benefits and risks in clinical practice. , 2021, Human reproduction update.
[13] A. Nakajima,et al. Cholestatic Liver Disease: Current Treatment Strategies and New Therapeutic Agents , 2021, Drugs.
[14] M. Ávila,et al. Fibrotic Events in the Progression of Cholestatic Liver Disease , 2021, Cells.
[15] S. Kane,et al. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis , 2021, The lancet. Gastroenterology & hepatology.
[16] J. Manson,et al. Recommended Hormone Therapy in Menopause: Concepts, Controversies and Approach to Treatment. , 2021, Endocrine reviews.
[17] J. Fleckenstein,et al. Intrahepatic Cholestasis of Pregnancy: Natural History and Current Management , 2021, Seminars in Liver Disease.
[18] Richard H. Lee,et al. Society for Maternal-Fetal Medicine (SMFM) Consult Series #53: Intrahepatic Cholestasis of Pregnancy. , 2020, American journal of obstetrics and gynecology.
[19] R. Dhiman,et al. Role of ursodeoxycholic acid on maternal serum bile acids and perinatal outcomes in intrahepatic cholestasis of pregnancy. , 2020, European journal of gastroenterology & hepatology.
[20] J. Hippisley-Cox,et al. Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases , 2020, BMJ.
[21] Lixin Sun,et al. The role of invariant natural killer T cells and associated immunoregulatory factors in triptolide-induced cholestatic liver injury. , 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[22] P. Middleton,et al. Pharmacological interventions for treating intrahepatic cholestasis of pregnancy. , 2020, The Cochrane database of systematic reviews.
[23] A. Montano‐Loza,et al. Definition and Management of Patients With Primary Biliary Cholangitis and an Incomplete Response to Therapy. , 2020, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
[24] Li-kun Gong,et al. Research progress on the protective effects of licorice-derived 18β-glycyrrhetinic acid against liver injury , 2020, Acta Pharmacologica Sinica.
[25] K. Kowdley,et al. Primary Sclerosing Cholangitis: Epidemiology, Genetics, Diagnosis, and Current Management , 2020, Clinical liver disease.
[26] E. Hadar,et al. Intrahepatic cholestasis of pregnancy as a risk factor for preeclampsia , 2020, Archives of Gynecology and Obstetrics.
[27] G. Hirschfield,et al. Primary biliary cholangitis: pathogenesis and therapeutic opportunities , 2019, Nature Reviews Gastroenterology & Hepatology.
[28] Shengjia Zhao,et al. An "essential herbal medicine"-licorice: A review of phytochemicals and its effects in combination preparations. , 2019, Journal of ethnopharmacology.
[29] Jennifer L. Bell,et al. Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial , 2019, The Lancet.
[30] P. Watkins,et al. Drug-induced liver injury , 2019, Nature Reviews Disease Primers.
[31] J. Hotaling,et al. The History of Estrogen Therapy. , 2019, Sexual medicine reviews.
[32] Olivier Michielin,et al. SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules , 2019, Nucleic Acids Res..
[33] S. Olafsson,et al. Biochemical response to ursodeoxycholic acid among PBC patients: a nationwide population-based study , 2019, Scandinavian journal of gastroenterology.
[34] Ageliki Tsagaratou. Unveiling the regulation of NKT17 cell differentiation and function , 2019, Molecular immunology.
[35] T. Berg,et al. Serum IP-10 levels and increased DPPIV activity are linked to circulating CXCR3+ T cells in cholestatic HCV patients , 2018, PloS one.
[36] M. Fischbach,et al. Bile acid metabolites control Th17 and Treg cell differentiation , 2018, bioRxiv.
[37] G. Prins,et al. Estrogens and prostate cancer , 2018, Prostate Cancer and Prostatic Diseases.
[38] Guo-zhen Xing,et al. 18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway , 2018, Acta Pharmacologica Sinica.
[39] Dandan Shi,et al. Celastrol Attenuates Intrahepatic Cholestasis of Pregnancy by Inhibiting Matrix Metalloproteinases-2 and 9. , 2018, Annals of hepatology.
[40] M. Kronenberg,et al. Tissue-specific functions of invariant natural killer T cells , 2018, Nature Reviews Immunology.
[41] L. Reis,et al. Estrogen therapy in patients with prostate cancer: a contemporary systematic review , 2018, International Urology and Nephrology.
[42] R. Chapman,et al. NI‐0801, an anti‐chemokine (C‐X‐C motif) ligand 10 antibody, in patients with primary biliary cholangitis and an incomplete response to ursodeoxycholic acid , 2018, Hepatology communications.
[43] K. Lindor,et al. Complications, symptoms, quality of life and pregnancy in cholestatic liver disease , 2018, Liver international : official journal of the International Association for the Study of the Liver.
[44] W. Liu,et al. Glycyrrhetic Acid Derivative TY501 Protects Against Lithocholic Acid–Induced Cholestasis , 2017, Drug Research.
[45] Min-jung Park,et al. Ursodeoxycholic acid attenuates experimental autoimmune arthritis by targeting Th17 and inducing pAMPK and transcriptional corepressor SMILE. , 2017, Immunology letters.
[46] F. Gonzalez,et al. Glycyrrhizin and glycyrrhetinic acid inhibits alpha-naphthyl isothiocyanate-induced liver injury and bile acid cycle disruption. , 2017, Toxicology.
[47] G. Minuk,et al. Diagnostic considerations for cholestatic liver disease , 2017, Journal of gastroenterology and hepatology.
[48] Ji-Eun Lee,et al. 18β-Glycyrrhetinic acid, the major bioactive component of Glycyrrhizae Radix, attenuates airway inflammation by modulating Th2 cytokines, GATA-3, STAT6, and Foxp3 transcription factors in an asthmatic mouse model. , 2017, Environmental toxicology and pharmacology.
[49] J. Burdette,et al. Phytosteroids beyond estrogens: Regulators of reproductive and endocrine function in natural products , 2017, Molecular and Cellular Endocrinology.
[50] A. S. Zepeda-Morales,et al. Liver fibrosis in bile duct-ligated rats correlates with increased hepatic IL-17 and TGF-β2 expression. , 2016, Annals of hepatology.
[51] Mudan Lu,et al. Resveratrol reduces matrix metalloproteinases and alleviates intrahepatic cholestasis of pregnancy in rats. , 2016, Canadian journal of physiology and pharmacology.
[52] Y. Chawla,et al. A molecular marker of disease activity in autoimmune liver diseases with histopathological correlation; FoXp3/RORγt ratio , 2015, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[53] Hyunyoung Jeong,et al. Estrogen-Induced Cholestasis Leads to Repressed CYP2D6 Expression in CYP2D6-Humanized Mice , 2015, Molecular Pharmacology.
[54] Mathias Dunkel,et al. SuperPred: update on drug classification and target prediction , 2014, Nucleic Acids Res..
[55] Yoshinobu Sato,et al. Increased activated natural killer T cells in the liver of patients with advanced stage primary biliary cirrhosis. , 2014, Biomedical research.
[56] Hyung Keun Kim,et al. 18β-Glycyrrhetinic acid from licorice root impairs dendritic cells maturation and Th1 immune responses , 2013, Immunopharmacology and immunotoxicology.
[57] Wenxiu Zhao,et al. 18β‐glycyrrhetinic acid inhibits hepatocellular carcinoma development by reversing hepatic stellate cell‐mediated immunosuppression in mice , 2013, International journal of cancer.
[58] G. Kolios,et al. CXCR3 axis in patients with primary biliary cirrhosis: a possible novel mechanism of the effect of ursodeoxycholic acid , 2013, Clinical and experimental immunology.
[59] B. Liu,et al. The Role of CXCR3 in the Induction of Primary Biliary Cirrhosis , 2011, Clinical & developmental immunology.
[60] Kai Huang,et al. PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach , 2010, Nucleic Acids Res..
[61] Chaoming Mao,et al. 18β-Glycyrrhetinic Acid Ameliorates Acute Propionibacterium acnes-induced Liver Injury through Inhibition of Macrophage Inflammatory Protein-1α* , 2009, The Journal of Biological Chemistry.
[62] OUP accepted manuscript , 2022, Nucleic Acids Research.
[63] M. Arrese,et al. UDCA, NorUDCA, and TUDCA in Liver Diseases: A Review of Their Mechanisms of Action and Clinical Applications. , 2019, Handbook of experimental pharmacology.
[64] F. Limongi. Th1 cytokines and chemokines in primary biliary cirrhosis. , 2015, La Clinica terapeutica.
[65] Brad T. Sherman,et al. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.