Decision Trees for Detection of Activity Intensity in Youth with Cerebral Palsy.

PURPOSE To develop and test decision tree (DT) models to classify physical activity (PA) intensity from accelerometer output and Gross Motor Function Classification System (GMFCS) classification level in ambulatory youth with cerebral palsy (CP) and compare the classification accuracy of the new DT models to that achieved by previously published cut points for youth with CP. METHODS Youth with CP (GMFCS levels I-III) (N = 51) completed seven activity trials with increasing PA intensity while wearing a portable metabolic system and ActiGraph GT3X accelerometers. DT models were used to identify vertical axis (VA) and vector magnitude (VM) count thresholds corresponding to sedentary (SED) (<1.5 METs), light-intensity PA (LPA) (≥1.5 and <3 METs) and moderate-to-vigorous PA (MVPA) (≥3 METs). Models were trained and cross-validated using the "rpart" and "caret" packages within R. RESULTS For the VA (VA_DT) and VM DT (VM_DT), a single threshold differentiated LPA from SED, whereas the threshold for differentiating MVPA from LPA decreased as the level of impairment increased. The average cross-validation accuracies for the VC_DT were 81.1%, 76.7%, and 82.9% for GMFCS levels I, II, and III. The corresponding cross-validation accuracies for the VM_DT were 80.5%, 75.6%, and 84.2%. Within each GMFCS level, the DT models achieved better PA intensity recognition than previously published cut points. The accuracy differential was greatest among GMFCS level III participants, in whom the previously published cut points misclassified 40% of the MVPA activity trials. CONCLUSIONS The GMFCS-specific cut points provide more accurate assessments of MVPA levels in youth with CP across the full spectrum of ambulatory ability.

[1]  Kelly M. Clanchy,et al.  Measurement of habitual physical activity performance in adolescents with cerebral palsy: a systematic review , 2011, Developmental medicine and child neurology.

[2]  Gert R. G. Lanckriet,et al.  A random forest classifier for the prediction of energy expenditure and type of physical activity from wrist and hip accelerometers , 2014, Physiological measurement.

[3]  S. Trost,et al.  Reliability and Validity of Objective Measures of Physical Activity in Youth With Cerebral Palsy Who Are Ambulatory , 2015, Physical Therapy.

[4]  J. R. Landis,et al.  The measurement of observer agreement for categorical data. , 1977, Biometrics.

[5]  Weng-Keen Wong,et al.  Machine learning for activity recognition: hip versus wrist data , 2014, Physiological measurement.

[6]  S. Trost,et al.  Clinical use of objective measures of physical activity , 2013, British Journal of Sports Medicine.

[7]  C. Metz Basic principles of ROC analysis. , 1978, Seminars in nuclear medicine.

[8]  J G Gamble,et al.  Energy Cost of Walking in Normal Children and in Those with Cerebral Palsy: Comparison of Heart Rate and Oxygen Uptake , 1989, Journal of pediatric orthopedics.

[9]  Brian T. Smith,et al.  Energy cost of walking in children with cerebral palsy: relation to the Gross Motor Function Classification System , 2004, Developmental medicine and child neurology.

[10]  Brian W. Timmons,et al.  Accelerometry: A Feasible Method to Quantify Physical Activity in Ambulatory and Nonambulatory Adolescents with Cerebral Palsy , 2012, International journal of pediatrics.

[11]  Gregory J Welk,et al.  Principles of design and analyses for the calibration of accelerometry-based activity monitors. , 2005, Medicine and science in sports and exercise.

[12]  John W Staudenmayer,et al.  Accelerometer prediction of energy expenditure: vector magnitude versus vertical axis. , 2009, Medicine and science in sports and exercise.

[13]  R. Mcmurray,et al.  Calibration of two objective measures of physical activity for children , 2008, Journal of sports sciences.

[14]  D. Schoeller,et al.  Body Composition and Energy Expenditure in Adolescents with Cerebral Palsy or Myelodysplasia , 1991, Pediatric Research.

[15]  Weng-Keen Wong,et al.  Artificial neural networks to predict activity type and energy expenditure in youth. , 2012, Medicine and science in sports and exercise.

[16]  M. Pierrynowski,et al.  Habitual Physical Activity Levels Are Associated with Biomechanical Walking Economy in Children with Cerebral Palsy , 2005, American journal of physical medicine & rehabilitation.

[17]  O. Verschuren,et al.  Muscle activation and energy-requirements for varying postures in children and adolescents with cerebral palsy. , 2014, The Journal of pediatrics.

[18]  T. Takken,et al.  Exercise training program in children and adolescents with cerebral palsy: a randomized controlled trial. , 2007, Archives of pediatrics & adolescent medicine.

[19]  J. Rose,et al.  Promotion of Physical Fitness and Prevention of Secondary Conditions for Children With Cerebral Palsy: Section on Pediatrics Research Summit Proceedings , 2007, Physical Therapy.

[20]  Robert W Armstrong,et al.  Definition and classification of cerebral palsy , 2007, Developmental medicine and child neurology.

[21]  M. Ketelaar,et al.  Health-Enhancing Physical Activity in Children With Cerebral Palsy: More of the Same Is Not Enough , 2013, Physical Therapy.

[22]  R. Ware,et al.  Validation of accelerometer cut points in toddlers with and without cerebral palsy. , 2014, Medicine and science in sports and exercise.

[23]  Max Kuhn,et al.  Building Predictive Models in R Using the caret Package , 2008 .

[24]  Wei-Yin Loh,et al.  Classification and regression trees , 2011, WIREs Data Mining Knowl. Discov..

[25]  Christine Detrembleur,et al.  Mechanical Work, Energetic Cost, and Gait Efficiency in Children With Cerebral Palsy , 2007, Journal of pediatric orthopedics.

[26]  P. Rosenbaum,et al.  Content validity of the expanded and revised Gross Motor Function Classification System , 2008, Developmental medicine and child neurology.

[27]  S. Trost,et al.  Measuring reliability and validity of the ActiGraph GT3X accelerometer for children with cerebral palsy: a feasibility study. , 2014, Journal of pediatric rehabilitation medicine.

[28]  M. Yeargin-Allsopp,et al.  Trends in the prevalence of cerebral palsy in a population-based study. , 2002, Pediatrics.

[29]  J. Becher,et al.  Ambulatory activity of children with cerebral palsy: which characteristics are important? , 2012, Developmental medicine and child neurology.

[30]  M. Fragala-Pinkham,et al.  The Scope of Pediatric Physical Therapy Practice in Health Promotion and Fitness for Youth With Disabilities , 2015, Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association.

[31]  Yvonne W Wu,et al.  Change in ambulatory ability of adolescents and young adults with cerebral palsy , 2007, Developmental medicine and child neurology.

[32]  P. Schantz,et al.  Evaluation of the Oxycon Mobile metabolic system against the Douglas bag method , 2010, European Journal of Applied Physiology.

[33]  Roslyn N. Boyd,et al.  Validity of accelerometry in ambulatory children and adolescents with cerebral palsy , 2011, European Journal of Applied Physiology.

[34]  D. Damiano,et al.  Health-Related Physical Fitness for Children With Cerebral Palsy , 2014, Journal of child neurology.

[35]  Basia Belza,et al.  Ambulatory Physical Activity Performance in Youth With Cerebral Palsy and Youth Who Are Developing Typically , 2007, Physical Therapy.

[36]  Diane L Damiano,et al.  Activity, Activity, Activity: Rethinking Our Physical Therapy Approach to Cerebral Palsy , 2006, Physical Therapy.

[37]  B. Abernethy,et al.  Physical activity measurement using MTI (actigraph) among children with cerebral palsy. , 2010, Archives of physical medicine and rehabilitation.

[38]  Stewart G. Trost,et al.  State of the Art Reviews: Measurement of Physical Activity in Children and Adolescents , 2007 .