Genetics and Diabetic Nephropathy

[1]  G. Chatellier,et al.  Association between high von Willebrand factor levels and the Thr789Ala vWF gene polymorphism but not with nephropathy in type I diabetes , 2000 .

[2]  A. Solini,et al.  Polymorphisms of angiotensin-converting enzyme and angiotensinogen genes in type 2 diabetic sibships in relation to albumin excretion rate. , 1999, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[3]  L. Groop,et al.  Heritability of albumin excretion rate in families of patients with Type II diabetes , 1999, Diabetologia.

[4]  K. Yamada,et al.  Association of an (A–C)n dinucleotide repeat polymorphic marker at the 5′‐region of the aldose reductase gene with retinopathy but not with nephropathy or neuropathy in Japanese patients with Type 2 diabetes mellitus , 1999, Diabetic medicine : a journal of the British Diabetic Association.

[5]  J. Gross,et al.  Familial clustering of diabetic nephropathy in Brazilian type 2 diabetic patients. , 1999, Diabetes.

[6]  A. Maxwell,et al.  Risk of developing diabetic nephropathy is not associated with synergism between the angiotensin II (type 1) receptor C1166 allele and poor glycaemic control. , 1999, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[7]  J. Ménard,et al.  Renal changes on hyperglycemia and angiotensin-converting enzyme in type 1 diabetes. , 1999, Hypertension.

[8]  R. Holman,et al.  Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. , 1998 .

[9]  T. Lehtimäki,et al.  Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism and Diabetic Albuminuria in Patients with NIDDM Followed Up for 9 Years , 1998, Nephron.

[10]  P. Talmud,et al.  Effect of angiotensin-converting enzyme (ACE) gene polymorphism on progression of renal disease and the influence of ACE inhibition in IDDM patients: findings from the EUCLID Randomized Controlled Trial. EURODIAB Controlled Trial of Lisinopril in IDDM. , 1998, Diabetes.

[11]  R. Eaton,et al.  Z-2 microsatellite allele is linked to increased expression of the aldose reductase gene in diabetic nephropathy. , 1998, The Journal of clinical endocrinology and metabolism.

[12]  D. Moczulski,et al.  Major susceptibility locus for nephropathy in type 1 diabetes on chromosome 3q: results of novel discordant sib-pair analysis. , 1998, Diabetes.

[13]  H. Parving,et al.  Diabetic nephropathy and the insertion/deletion polymorphism of the angiotensin-converting enzyme gene. , 1998, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[14]  R. Hanson,et al.  Sib-pair linkage analysis for susceptibility genes for microvascular complications among Pima Indians with type 2 diabetes. Pima Diabetes Genes Group. , 1998, Diabetes.

[15]  D. Moczulski,et al.  Diabetic nephropathy is associated with AGT polymorphism T235: results of a family-based study. , 1998, Hypertension.

[16]  J. Staessen,et al.  The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular‐renal risk , 1997, Journal of hypertension.

[17]  D. Dunger,et al.  Lack of association of angiotensin II type 1 receptor gene polymorphism with diabetic nephropathy in insulin‐dependent diabetes mellitus , 1997, Diabetic medicine : a journal of the British Diabetic Association.

[18]  O. B. O. T. I. Group,et al.  Clustering of albumin excretion rate abnormalities in Caucasian patients with NIDDM , 1997, Diabetologia.

[19]  G Chatellier,et al.  Contribution of genetic polymorphism in the renin-angiotensin system to the development of renal complications in insulin-dependent diabetes: Genetique de la Nephropathie Diabetique (GENEDIAB) study group. , 1997, The Journal of clinical investigation.

[20]  M. Hibberd,et al.  Polymorphism in the 5′-End of the Aldose Reductase Gene Is Strongly Associated With the Development of Diabetic Nephropathy in Type I Diabetes , 1997, Diabetes.

[21]  A. Kaider,et al.  Evaluation of risk factors for the development of nephropathy in patients with IDDM: insertion/deletion angiotensin converting enzyme gene polymorphism, hypertension and metabolic control , 1997, Diabetologia.

[22]  L. Tarnow,et al.  Genetics of diabetic nephropathy. , 1996, Journal of the American Society of Nephrology : JASN.

[23]  F. Cambien,et al.  Effect of deletion polymorphism of angiotensin converting enzyme gene on progression of diabetic nephropathy during inhibition of angiotensin converting enzyme: observational follow up study , 1996, BMJ.

[24]  H. Parving,et al.  Nephrology Dialysis Transplantation Angiotensin-II type 1 receptor gene polymorphism and diabetic microangiopathy , 2005 .

[25]  W. Sheu,et al.  Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22. , 1996, The Journal of clinical investigation.

[26]  L. Tarnow.  Genetic pattern in diabetic nephropathy. , 1996, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[27]  S. Kawazu,et al.  Association analyses of the polymorphisms of angiotensin-converting enzyme and angiotensinogen genes with diabetic nephropathy in Japanese non-insulin-dependent diabetics. , 1996, Metabolism: clinical and experimental.

[28]  H. Scheffer,et al.  Association between angiotensin-converting-enzyme gene polymorphism and failure of renoprotective therapy , 1996, The Lancet.

[29]  I. Stratton,et al.  U.K. Prospective Diabetes Study. XV: Relationship of renin-angiotensin system gene polymorphisms with microalbuminuria in NIDDM. , 1995, Kidney international.

[30]  I. Ichikawa,et al.  Role of the deletion of polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy. , 1995, The Journal of clinical investigation.

[31]  R. Trevisan,et al.  Genetic factors in the development of diabetic nephropathy. , 1995, The Journal of laboratory and clinical medicine.

[32]  J E Tooke,et al.  Microvascular Function in Human Diabetes: A Physiological Perspective , 1995, Diabetes.

[33]  K. Lam,et al.  An (A-C)n dinucleotide repeat polymorphic marker at the 5' end of the aldose reductase gene is associated with early-onset diabetic retinopathy in NIDDM patients. , 1995, Diabetes.

[34]  T. Ogihara,et al.  Angiotensin I-Converting Enzyme Gene Polymorphism Is Associated With Myocardial Infarction, but Not With Retinopathy or Nephropathy, in NIDDM , 1995, Diabetes Care.

[35]  J. Connell,et al.  Polymorphisms in angiotensin-converting-enzyme gene and progression of IgA nephropathy , 1995, The Lancet.

[36]  J. Ménard,et al.  Angiotensin-converting enzyme gene polymorphism has no influence on the circulating renin-angiotensin-aldosterone system or blood pressure in normotensive subjects. , 1995, Circulation.

[37]  J. Connell,et al.  Enhanced pressor response to angiotensin I in normotensive men with the deletion genotype (DD) for angiotensin-converting enzyme. , 1995, Hypertension.

[38]  A. Krolewski,et al.  Glycosylated hemoglobin and the risk of microalbuminuria in patients with insulin-dependent diabetes mellitus. , 1995, The New England journal of medicine.

[39]  H. Parving,et al.  Lack of Relationship Between an Insertion/Deletion Polymorphism in the Angiotensin I–Converting Enzyme Gene and Diabetic Nephropathy and Proliferative Retinopathy in IDDM Patients , 1995, Diabetes.

[40]  E. Ritz,et al.  Association of ACE gene polymorphism and diabetic nephropathy? The Diabetic Nephropathy Study Group. , 1995, Kidney international.

[41]  B. Feldt-Rasmussen,et al.  Effect of low-dose heparin on urinary albumin excretion in insulin-dependent diabetes mellitus , 1995, The Lancet.

[42]  H. Parving,et al.  The insertion/deletion polymorphism in the angiotensin I-converting enzyme gene predicts the progression of diabetic nephropathy during ACE inhibition in insulin dependent diabetic patients , 1995 .

[43]  G. Watts,et al.  Role of glycaemic control in development of microalbuminuria in patients with insulin dependent diabetes , 1994, BMJ.

[44]  L. Tiret,et al.  Plasma Level and Gene Polymorphism of Angiotensin‐Converting Enzyme in Relation to Myocardial Infarction , 1994, Circulation.

[45]  L. Tiret,et al.  Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension. , 1994, Hypertension.

[46]  H. Schunkert,et al.  Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy. , 1994, The New England journal of medicine.

[47]  A. Krolewski,et al.  Genetic Predisposition to Diabetic Nephropathy: Evidence for a Role of the Angiotensin I–Converting Enzyme Gene , 1994, Diabetes.

[48]  F. Cambien,et al.  Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[49]  F. Cambien,et al.  Relationships Between Angiotensin I Converting Enzyme Gene Polymorphism, Plasma Levels, and Diabetic Retinal and Renal Complications , 1994, Diabetes.

[50]  R. Bain,et al.  The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group. , 1993, The New England journal of medicine.

[51]  M. B. Perryman,et al.  Angiotensin-converting enzyme DD genotype in patients with ischaemic or idiopathic dilated cardiomyopathy , 1993, The Lancet.

[52]  A. Marian,et al.  Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death , 1993, The Lancet.

[53]  S. Genuth,et al.  The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. , 1993, The New England journal of medicine.

[54]  J. Nyengaard,et al.  Hyperglycemic Pseudohypoxia and Diabetic Complications , 1993, Diabetes.

[55]  G. Remuzzi,et al.  Heterogeneous nature of renal lesions in type II diabetes. , 1993, Journal of the American Society of Nephrology : JASN.

[56]  Steven C. Hunt,et al.  Molecular basis of human hypertension: Role of angiotensinogen , 1992, Cell.

[57]  Philippe Amouyel,et al.  Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction , 1992, Nature.

[58]  L. Tiret,et al.  Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. , 1992, American journal of human genetics.

[59]  A. Fitzgerald,et al.  Prospective Study of Microalbuminuria as Predictor of Mortality in NIDDM , 1992, Diabetes.

[60]  H. Parving,et al.  Is diabetic nephropathy an inherited complication? , 1992, Kidney international.

[61]  K. Earle,et al.  Familial clustering of cardiovascular disease in patients with insulin-dependent diabetes and nephropathy. , 1992, The New England journal of medicine.

[62]  P Corvol,et al.  An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. , 1990, The Journal of clinical investigation.

[63]  E. G. Erdös,et al.  Angiotensin I converting enzyme and the changes in our concepts through the years. Lewis K. Dahl memorial lecture. , 1990, Hypertension.

[64]  E. Seaquist,et al.  Familial clustering of diabetic kidney disease. Evidence for genetic susceptibility to diabetic nephropathy. , 1989, The New England journal of medicine.

[65]  F. Cambien,et al.  Familial resemblance of plasma angiotensin-converting enzyme level: the Nancy Study. , 1988, American journal of human genetics.

[66]  J. Ménard,et al.  Prevention of diabetic nephropathy with enalapril in normotensive diabetics with microalbuminuria. , 1988, BMJ.

[67]  H. Danielsen,et al.  Acute and Long‐term Renal Effects of Angiotensin Converting Enzyme Inhibition in Normotensive, Normoalbuminuric Insulin‐dependent Diabetic Patients , 1988, Diabetic medicine : a journal of the British Diabetic Association.

[68]  J. Flier,et al.  Epidemiologic approach to the etiology of type I diabetes mellitus and its complications. , 1987, The New England journal of medicine.

[69]  H. Keen,et al.  Raised arterial pressure in parents of proteinuric insulin dependent diabetics. , 1987, British medical journal.

[70]  M. Marre,et al.  Converting enzyme inhibition and kidney function in normotensive diabetic patients with persistent microalbuminuria. , 1987, British medical journal.

[71]  B. Brenner,et al.  Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension. , 1986, The Journal of clinical investigation.

[72]  Y. Taguma,et al.  Effect of captopril on heavy proteinuria in azotemic diabetics. , 1985, The New England journal of medicine.

[73]  G. Viberti,et al.  Microalbuminuria Predicts Mortality in Noninsulin‐dependent Diabetes , 1984, Diabetic medicine : a journal of the British Diabetic Association.

[74]  C. Mogensen,et al.  Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. , 1984, The New England journal of medicine.

[75]  N. Lassen,et al.  Hemodynamic factors in the genesis of diabetic microangiopathy. , 1983, Metabolism: clinical and experimental.

[76]  B. Brenner,et al.  Glomerular hemodynamics in experimental diabetes mellitus. , 1981, Kidney international.

[77]  A. Sastre,et al.  Serum angiotensin-converting enzyme: elevations in diabetes mellitus. , 1980, Annals of internal medicine.

[78]  T. Lohmeier,et al.  Control of glomerular filtration rate by renin-angiotensin system. , 1977, The American journal of physiology.

[79]  A. Michael,et al.  Studies of the Rate of Regression of the Glomerular Lesions in Diabetic Rats Treated with Pancreatic Islet Transplantation , 1975, Diabetes.

[80]  R. Unger,et al.  Studies of muscle capillary basement membranes in normal subjects, diabetic, and prediabetic patients. , 1968, The Journal of clinical investigation.

[81]  R. Hanson,et al.  Familial Factors in Diabetic Nephropathy , 2000 .

[82]  S. Hadjadj,et al.  Contribution of Angiotensin I Converting Enzyme I/D polymorphism to the development and progression of diabetic nephropathy in type 1 diabetes: a 6-year follow-up observational study , 1999 .

[83]  T. Ogihara,et al.  Meta-analysis of association of insertion/deletion polymorphism of angiotensin I-converting enzyme gene with diabetic nephropathy and retinopathy , 1998, Diabetologia.

[84]  K. Thai,et al.  Angiotensin converting enzyme gene polymorphism and renal hemodynamic function in early diabetes. , 1997, Kidney international.

[85]  J. Staessen,et al.  The insertion/deletion polymorphism of the angiotensin-converting enzyme gene and car-diovascular-renal risk : a meta-analysis , 1997 .

[86]  H. Hemmi,et al.  Angiotensin-converting enzyme polymorphism and development of diabetic nephropathy in non-insulin-dependent diabetes mellitus. , 1995, Nephron.

[87]  B. Brenner,et al.  Hemodynamically mediated glomerular injury and the progressive nature of kidney disease. , 1983, Kidney international.

[88]  J. Vane.  Sites of Conversion of Angiotensin I , 1972 .